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Zu "K05660" wurden 44 Artikel gefunden!
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Artikelnummer: TGM-T2S0223-1mg
Description: 1. Isosinensetin (6-Demethoxynobiletin) shows antioxidant and HIV-1 protease inhibiting activities. Target: HIV Protease, Antioxidant, Antibacterial, P-gp. Smiles: COc1ccc(cc1OC)-c1cc(=O)c2c(OC)cc(OC)c(OC)c2o1. References: Jiang Y , Wong J H , Fu M , et al. Isolation of adenosine, iso-sinensetin and...
Schlagworte: | 6-Demethoxynobiletin |
Anwendung: | Polymethoxylated flavone, anticancer / anti-inflammatory agent |
CAS | 17290-70-9 |
MW: | 372.37 D |
ab 59,00 €
Artikelnummer: TGM-T72678-100mg
Description: P-gp inhibitor 4 is a selective P-glycoprotein modulator with an EC 50 of 94 nM. P-gp inhibitor 4 increases drug transport across gastro-intestinal barrier and recovers doxorubicin toxicity in multidrug resistant cancer cells . Target: Others. Smiles:...
Anwendung: | P-gp (ABCB5) inhibitor |
CAS | 2652001-05-1 |
MW: | 714.85 D |
ab 1.491,00 €
Artikelnummer: TGM-T72739-100mg
Description: P-gp Inhibitor 2 is a powerful P-glycoprotein (P-gp) inhibitor, effective in reversing Doxorubicin resistance with an IC50 of 0.22 µM in human colorectal carcinoma cells overexpressing P-gp (SW600 Ad300). Target: Others. Smiles:...
Anwendung: | P-gp (ABCB5) inhibitor |
CAS | 2408406-89-1 |
MW: | 498.53 D |
ab 3.701,00 €
Artikelnummer: TGM-TMPJ-01145-10ug
Description: ATP-binding cassette sub-family B member 5(ABCB5) is a plasma membrane-spanning protein. ABCB5 is principally expressed in physiological skin and human malignant melanoma. ABCB5 has been suggested to regulate skin progenitor cell fusion and mediate chemotherapeutic drug resistance in stem-like tumor...
Schlagworte: | P-glycoprotein ABCB5, ABCB5, ATP-binding cassette sub-family B member 5, ABCB5 P-gp |
MW: | 30 kD |
ab 180,00 €
Artikelnummer: TGM-T63608-100mg
Description: P-gp inhibitor 5 is a potent P-glycoprotein (P-gp) inhibitor, reducing P-gp activity by a factor of 2.5 and 3.0 at 1.25 µM and 2.5 µM, respectively. It exhibits anti-proliferative effects on certain cancer cells and restores cellular sensitivity to Vincristine and Paclitaxel, reversing the multidrug...
Anwendung: | P-gp (ABCB5) inhibitor |
CAS | 2451298-06-7 |
MW: | 517.98 D |
ab 1.491,00 €
Artikelnummer: TGM-T12341-100mg
Description: P-gp inhibitor 1 inhibits reversing P-glycoprotein-mediated multidrug resistance with an EC50 of 57.9 nM (K562/A02 cells). Target: P-gp, Others. Smiles: COc1cc2CCN(CCc3ccc(Nc4nc(nc5ccccc45)-c4ccncc4)cc3)Cc2cc1OC. References: Qiu Q, et al. Design, Synthesis, and Pharmacological Characterization of...
Anwendung: | P-gp (ABCB5) inhibitor |
CAS | 2050747-49-2 |
MW: | 517.62 D |
ab 32,00 €
Artikelnummer: TGM-T27985-2mg
Description: MC-70 is a potent P-glycoprotein (P-gp) inhibitor (EC50 = 0.69 µM). Target: Others. Smiles: O(C)C=1C=C2C(CN(CC3=CC=C(C=C3)C4=CC=C(O)C=C4)CC2)=CC1OC. References: Guglielmo S, Lazzarato L, Contino M, Perrone MG, Chegaev K, Carrieri A, Fruttero R, Colabufo NA, Gasco A. SAR Studies on Tetrahydroisoquinoline...
Schlagworte: | MC 70, MC70 |
Anwendung: | P-gp inhibitor |
CAS | 1031367-64-2 |
MW: | 375.46 D |
44,00 €
Artikelnummer: CSB-MA000232.100
Host Species: Mouse. Isotype: IgG. Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific...
Schlagworte: | Anti-ABCB5, Anti-ABCB5 P-gp, Anti-P-glycoprotein ABCB5, Anti-ATP-binding cassette sub-family B member 5, ABCB5,... |
Anwendung: | ELISA, WB |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
ab 106,00 €
Artikelnummer: CSB-PA181054.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ABCB5. Antigen Species: Human
Schlagworte: | Anti-ABCB5, Anti-ABCB5 P-gp, Anti-P-glycoprotein ABCB5, Anti-ATP-binding cassette sub-family B member 5, ABCB 5 antibody,... |
Anwendung: | ELISA, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Artikelnummer: CSB-PA967715.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ABCB5. Antigen Species: Human
Schlagworte: | Anti-ABCB5, Anti-ABCB5 P-gp, Anti-P-glycoprotein ABCB5, Anti-ATP-binding cassette sub-family B member 5, ABCB 5 antibody,... |
Anwendung: | ELISA, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Artikelnummer: NSJ-RQ5509
0.5mg/ml if reconstituted with 0.2ml sterile DI water. ATP-binding cassette sub-family B member 5 also known as P-glycoprotein ABCB5 is a plasma membrane-spanning protein that in humans is encoded by the ABCB5 gene.It is mapped to 7p21.1. ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of...
Schlagworte: | Anti-ABCB5 P-gp, Anti-P-glycoprotein ABCB5, Anti-ATP-binding cassette sub-family B member 5, ABCB5 Antibody |
Anwendung: | IHC (paraffin), FC, Direct ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Artikelnummer: 600-401-A77
Protein function: Plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Responsible for the resistance to doxorubicin of a subset of malignant melanomas. [The UniProt Consortium]
Schlagworte: | Anti-ABCB5, Anti-ABCB5 P-gp, Anti-P-glycoprotein ABCB5, Anti-ATP-binding cassette sub-family B member 5 |
Anwendung: | ELISA, IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 180,00 €