Zu "K05658" wurden 151 Artikel gefunden!
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Anti-ABCB1
Artikelnummer: ABS-KC-2764.100
Protein function: Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine,...
| Schlagworte: | Anti-ATP-dependent translocase ABCB1, Anti-ATP-binding cassette sub-family B member 1, Anti-Multidrug resistance protein... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-ABCB1
Artikelnummer: ABS-KC-2776.100
Protein function: Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine,...
| Schlagworte: | Anti-ATP-dependent translocase ABCB1, Anti-ATP-binding cassette sub-family B member 1, Anti-Multidrug resistance protein... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
Anti-ABCB1
Artikelnummer: ABS-OC-362.100
Protein function: Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine,...
| Schlagworte: | Anti-ATP-dependent translocase ABCB1, Anti-ATP-binding cassette sub-family B member 1, Anti-Multidrug resistance protein... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
ABCB1 (human), recombinant protein
Artikelnummer: ABS-PP-118.20
| Schlagworte: | ATP-dependent translocase ABCB1, ATP-binding cassette sub-family B member 1, Multidrug resistance protein 1,... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 33 kD |
ab 90,00 €
ABCB1 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-00981-100ug
Description: ABCB1 Protein, Human, Recombinant (His) is expressed in E. coli.
| Schlagworte: | Phospholipid transporter ABCB1, CD243, ATP-dependent translocase ABCB1, ATP-binding cassette sub-family B member 1,... |
| MW: | 44.2 kD |
ab 198,00 €
Dihydromethysticin
Artikelnummer: TGM-TQ0191-10mg
Description: Dihydromethysticin ((+)-Dihydromethysticin) is a kavalactone found in Piper methysticum. It has marked activity on the induction of CYP3A23. Target: P450. Smiles: COC1=CC(=O)O[C@@H](CCc2ccc3OCOc3c2)C1. References: Ma Y, et al. Desmethoxyyangonin and dihydromethysticin are two major pharmacological...
| Schlagworte: | (+)-Dihydromethysticin |
| Anwendung: | Bioactive kavalactone, P-gp inhibitor |
| CAS | 19902-91-1 |
| MW: | 276.28 D |
ab 71,00 €
Biricodar dicitrate
Artikelnummer: TGM-T67790-100mg
Description: Biricodar dicitrate (VX-710) is a potent MDR inhibitor with no anticancer activity and can be used to study prostate cancer. Target: NF-kappaB, AChR. Smiles: OC(CC(C(O)=O)(O)CC(O)=O)=O.O=C(C1=CC(OC)=C(C(OC)=C1)OC)C(N2[C@@H](CCCC2)C(OC(CCCC3=CN=CC=C3)CCCC4=CN=CC=C4)=O)=O.OC(CC(C(O)=O)(O)CC(O)=O)=O....
| Schlagworte: | VX 710, VX 710-3 |
| Anwendung: | Targets ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2] (ABCB1, CD243) |
| CAS | 174254-13-8 |
| MW: | 987.95 D |
ab 516,00 €
Zosuquidar trihydrochloride
Artikelnummer: TGM-T6018-10mg
Description: Zosuquidar trihydrochloride (LY-335979 trihydrochloride) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of 60 nM. Phase 3. Target: P-gp. Smiles: Cl.Cl.Cl.OC(COc1cccc2ncccc12)CN1CCN(CC1)C1c2ccccc2C2C(c3ccccc13)C2(F)F. References: Dantzig AH, et al. Cancer Res. 1996,...
| Schlagworte: | Zosuquidar 3HCl, Zosuquidar (LY335979) 3HCl, RS 33295-198 trihydrochloride, RS 33295-198 (D06387) 3HCl, LY-335979... |
| Anwendung: | Targets ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2] (ABCB1, CD243) |
| CAS | 167465-36-3 |
| MW: | 636.99 D |
ab 31,00 €
ONT-093
Artikelnummer: TGM-T63338-10mg
Description: ONT-093, a potent inhibitor of the P-glycoprotein pump, has significant potential for investigating cancer diseases. Target: Others. Smiles: N(C(C)C)C1=CC=C(C2=C(N=C(N2)C3=CC=C(/C=C/COCC)C=C3)C4=CC=C(NC(C)C)C=C4)C=C1
| Anwendung: | P-glycoprotein pump inhibitor |
| CAS | 216227-54-2 |
| MW: | 494.67 D |
ab 42,00 €
Tariquidar
Artikelnummer: TGM-T6287-100mg
Description: Tariquidar (XR9576)(Kd=5.1 nM) is a specific and effective non-competitive inhibitor of P-glycoprotein. It can reverse drug resistance in MDR cell Lines. Target: P-gp. Smiles: COc1cc2CCN(CCc3ccc(NC(=O)c4cc(OC)c(OC)cc4NC(=O)c4cnc5ccccc5c4)cc3)Cc2cc1OC. References: Martin C, et al. Br J Pharmacol, 1999,...
| Schlagworte: | XR9576 |
| Anwendung: | Targets ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2] (ABCB1, CD243) |
| CAS | 206873-63-4 |
| MW: | 646.73 D |
ab 45,00 €
Rhodamine 123
Artikelnummer: TGM-T16743-5mg
Description: Rhodamine 123 is a fluorescent dye (lambdaex=503 nm, lambdaem=527 nm). Target: Others. Smiles: COC(C1=CC=CC=C1C2=C3C=CC(N)=CC3=[O+]C4=C2C=CC(N)=C4)=O.[Cl-]. References: M. Huang, et al. Mitochondrial Inner Membrane Electrophysiology Assessed by Rhodamine-123 Transport and Fluorescence. Ann Biomed Eng....
| Schlagworte: | RH-123, R-22420 |
| Anwendung: | Membrane-permeable cationic dye, P-glycoprotein substrate, mitochondrial stain |
| CAS | 62669-70-9 |
| MW: | 380.83 D |
ab 46,00 €
Valspodar
Artikelnummer: TGM-T17216-10mg
Description: Valspodar (PSC 833), a specific P-glycoprotein inhibitor and MDR regulator, is commonly used as a chemical sensitizer in the study of advanced epithelial ovarian cancer. Target: P-gp. Smiles:...
| Schlagworte: | PSC 833 |
| Anwendung: | Targets ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2] (ABCB1, CD243) |
| CAS | 121584-18-7 |
| MW: | 1214.62 D |
ab 287,00 €