Zu "K05222" wurden 100 Artikel gefunden!
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Transient receptor potential cation channel subfamily V...
Artikelnummer: CSB-CF822774HU1.100
Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 39-839aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: QLSTAKSRTR LFGKGDSEEA FPVDCPHEEG ELDSCPTITV SPVITIQRPG DGPTGARLLS QDSVAASTEK TLRLYDRRSI FEAVAQNNCQ DLESLLLFLQ KSKKHLTDNE...
| Schlagworte: | VR1, TrpV1, TRPV1, OTRPC1, Capsaicin receptor, Vanilloid receptor 1, Osm-9-like TRP channel 1, Transient receptor... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli in vitro |
| Ursprungsart: | human |
| MW: | 92.5 kD |
ab 799,00 €
Resiniferatoxin
Artikelnummer: TGM-T34295-1mg
Description: Resiniferatoxin ([3H]resiniferatoxin) inhibits the production of Th1 cytokines, contributing to the defense against T. spiralis infection, and can be used in studies about the modulator of the immune response. Target: IL Receptor. Smiles:...
| Schlagworte: | [3H]resiniferatoxin, RTX |
| Anwendung: | Highly potent TRPV1 agonist |
| CAS | 57444-62-9 |
| MW: | 628.71 D |
455,00 €
Hydroxy-alpha-sanshool
Artikelnummer: TGM-T8307-100mg
Description: Hydroxy-alpha-sanshool is an alkyl amide isolated from the pepper. It acts as a TRPA1 covalent and TRPV1 non-covalent agonist (EC50s: 69 and 1.1 µM). Target: Endogenous Metabolite, TRP/TRPV Channel. Smiles: C\C=C\C=C\C=C/CC\C=C\C(=O)NCC(C)(C)O. References: Koo JY, et al. Compounds from Sichuan and...
| Schlagworte: | Hydroxy-alpha-sanshool |
| Anwendung: | TRPV1/TRPA1 agonist |
| CAS | 83883-10-7 |
| MW: | 263.38 D |
ab 98,00 €
Motugivatrep
Artikelnummer: TGM-T64312-100mg
Description: Motugivatrep is a potent type 1 transient receptor potential (TRPV1) antagonist and has a broad role in the treatment of drug, urinary tract and respiratory diseases. Target: Others. Smiles: C(\C(NC1=C2C(=CC=C1)CC[C@@H](O)C2)=O)=C\3/C=4C(=CC(C(F)(F)F)=CC4)OCC3
| Anwendung: | Targets transient receptor potential cation channel subfamily V member 1 (TRPV1) |
| CAS | 920332-28-1 |
| MW: | 403.39 D |
ab 2.142,00 €
AMG 517
Artikelnummer: TGM-T6379-100mg
Description: AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM), and heat activation (IC50: 1.3 nM) of TRPV1. Target: TRP/TRPV Channel. Smiles: O(C1=C2C(SC(NC(C)=O)=N2)=CC=C1)C=3C=C(N=CN3)C4=CC=C(C(F)(F)F)C=C4. References: Gavva NR, et al. J Pharmacol...
| Schlagworte: | AMG-517, AMG517 |
| Anwendung: | TRPV1 antagonist |
| CAS | 659730-32-2 |
| MW: | 430.4 D |
ab 46,00 €
Dihydrocapsiate
Artikelnummer: TGM-T60741-100mg
Description: Dihydrocapsiate is a compound of capsinoid family that can be used in metabolism diseas research. Dihydrocapsiate is an orally active agonist of TRPV1 [1]. Target: Others. Smiles: COc1cc(COC(=O)CCCCCCC(C)C)ccc1O
| Anwendung: | TRPV1 agonist |
| CAS | 205687-03-2 |
| MW: | 308.41 D |
ab 970,00 €
Capsaicin
Artikelnummer: Cay92350-100
Capsaicin is a terpene alkaloid that has been found in Capsicum and has diverse biological activities. It induces inward currents in HEK293 cells expressing rat transient receptor potential vanilloid 1 (TRPV1, EC50 = 0.64 µM at neutral pH), an effect that can be blocked by the TRPV1 inhibitor A-425619. Capsaicin (10...
| Schlagworte: | N-[(4-hydroxy-3-methoxyphenyl)methyl]-6E-8-methyl-nonenamide |
| CAS | 404-86-4 |
| MW: | 305.4 D |
ab 117,00 €
Nonivamide
Artikelnummer: TGM-T1321-100mg
Description: Nonivamide (Nonanoic acid vanillylamide) is found in herbs and spices. Nonivamide is an alkaloid from Capsicum species Nonivamide is a flavoring ingredient. Nonivamide is an organic compound and a capsaicinoid. It is an amide of pelargonic acid and vanillylamine. It is present in chili peppers, but is...
| Schlagworte: | Nonanoic acid vanillylamide, Pseudocapsaicin, Vanillyl-N-nonylamide, Pelargonic acid vanillylamide |
| Anwendung: | Targets transient receptor potential cation channel subfamily V member 1 (TRPV1) |
| CAS | 2444-46-4 |
| MW: | 293.4 D |
ab 49,00 €
QX-314 chloride
Artikelnummer: TGM-T12608-100mg
Description: QX-314 chloride is a membrane-impermeable, permanently charged blocker of the sodium channel. Target: Sodium Channel. Smiles: [Cl-].CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C. References: Rivera-Acevedo RE, et al. The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor...
| Anwendung: | Sodium channel blocker |
| CAS | 5369-03-9 |
| MW: | 298.85 D |
ab 48,00 €
JYL 1421
Artikelnummer: TGM-T15634-100mg
Description: JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM). Target: TRP/TRPV Channel. Smiles: CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1. References: Jakab B, et al. Pharmacological characterization of the TRPV1 receptor antagonist JYL1421 (SC0030) in vitro and in vivo in the rat. Eur...
| Schlagworte: | SC 0030 |
| Anwendung: | Selective TRPV1 receptor antagonist |
| CAS | 401907-26-4 |
| MW: | 423.57 D |
ab 766,00 €
Mavatrep
Artikelnummer: TGM-T16014-100mg
Description: Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can be used for studies about inflammatory pain. Target: TRP/TRPV Channel. Smiles: CC(C)(O)c1ccccc1-c1ccc2nc(\C=C\c3ccc(cc3)C(F)(F)F)[nH]c2c1. References: Parsons WH, et al. Benzo[d]imidazole Transient Receptor Potential...
| Schlagworte: | JNJ-39439335 |
| Anwendung: | Targets transient receptor potential cation channel subfamily V member 1 (TRPV1) |
| CAS | 956274-94-5 |
| MW: | 422.44 D |
ab 60,00 €
Dihydrocapsaicin
Artikelnummer: TGM-T2163-100mg
Description: Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an irritant. Capsaicin is found in natural hot pepper extracts along with a number of...
| Schlagworte: | 8-Methyl-N-vanillylnonanamide, 6,7-Dihydrocapsaicin, CCRIS1589 |
| Anwendung: | Natural product, VR1 agonist |
| CAS | 19408-84-5 |
| MW: | 307.43 D |
ab 48,00 €