Zu "K05210" wurden 124 Artikel gefunden!
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NEU
GRIN2B (human), recombinant protein
Artikelnummer: ABS-PP-424.20
| Schlagworte: | Glutamate receptor ionotropic, NMDA 2B, GluN2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 17.5 kD |
ab 90,00 €
Rislenemdaz
Artikelnummer: TGM-T12733-100mg
Description: Rislenemdaz (CERC-301) (CERC-301) is an antagonist of the N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B). Target: iGluR. Smiles: Cc1ccc(COC(=O)N2CC[C@H](CNc3ncccn3)[C@H](F)C2)cc1. References: Rachel Garner, et al. Preclinical pharmacology and pharmacokinetics of CERC-301, a GluN2B-selective...
| Schlagworte: | MK-0657, CERC-301 |
| Anwendung: | Targets glutamate receptor ionotropic, NMDA 2B (GRIN2B) |
| CAS | 808732-98-1 |
| MW: | 358.41 D |
ab 98,00 €
Ro 25-6981 Maleate
Artikelnummer: TGM-T12758L-10mg
Description: Ro 25-6981 Maleate is a potent and selective activity-dependent NMDA receptor blocker, specifically targeting the NR2B subunit (IC50 values are 0.009 µM for NR1C/NR2B and 52 µM for NR1C/NR2A receptor subunit combinations). Target: NMDAR. Smiles:...
| Schlagworte: | Ro 256981 Maleate, Ro-25-6981 Maleate |
| Anwendung: | NMDA receptor NR2B subunit antagonist |
| CAS | 1312991-76-6 |
| MW: | 455.54 D |
ab 34,00 €
Gentiopicroside
Artikelnummer: TGM-T2770-100mg
Description: Gentiopicroside (Gentiopicrin), a naturally occurring iridoid glycoside, extracted from Gentiana manshurica Kitag, inhibits P450 activity, with an IC50 and a Ki of 61 µM and 22.8 µM for CYP2A6, has antianti-inflammatoryand antioxidative effects. Target: HCV Protease, P450. Smiles:...
| Schlagworte: | Gentiopicrin |
| Anwendung: | GRIN2B NMDAR downregulation |
| CAS | 20831-76-9 |
| MW: | 356.32 D |
ab 40,00 €
Neramexane Mesylate
Artikelnummer: TGM-T28158-100mg
Description: Neramexane is an NMDA antagonist with neuroprotective effects. Neramexane has antidepressant and nootropic actions. It also acts as a nicotinic acetylcholine receptor antagonist. Target: Others. Smiles: O=S(=O)(O)C.NC1(C)CC(C)(C)CC(C)(C)C1. References: Suckfüll M, Althaus M, Ellers-Lenz B, Gebauer A,...
| Schlagworte: | KRP209, KRP 209, KRP-209 |
| Anwendung: | Targets glutamate receptor ionotropic, NMDA 2B (GRIN2B) |
| CAS | 457068-92-7 |
| MW: | 265.41 D |
ab 1.520,00 €
Besonprodil
Artikelnummer: TGM-T30428-100mg
Description: Besonprodil is a drug that acts as an NMDA antagonist and is selective for the NR2B subunit. Target: Others. Smiles: S(CCN1CCC(CC2=CC=C(F)C=C2)CC1)(=O)C=3C=C4C(=CC3)NC(=O)O4. References: Ouattara B, Hoyer D, Grégoire L, Morissette M, Gasparini F, Gomez-Mancilla B, Di Paolo T. Changes of AMPA receptors...
| Schlagworte: | CHEMBL219631, 253450-09-8, UNII-5K3N2D15WW, Besonprodil (USAN), CI-1041 |
| Anwendung: | Targets glutamate receptor ionotropic, NMDA 2B (GRIN2B) |
| CAS | 253450-09-8 |
| MW: | 402.48 D |
ab 1.671,00 €
CAY10608
Artikelnummer: TGM-T37671-10mg
Description: N-Methyl-D-aspartate (NMDA) receptors are Ca2+ permeable ligand-gated channels of the central nervous system that are activated after binding of the co-agonists glutamate and glycine. CAY10608 is a propanolamine that potently, selectively, and non-competitively antagonizes the NR2B subunit of NMDA...
| Schlagworte: | CAY10608 |
| Anwendung: | NMDA receptor NR2B subunit antagonist |
| CAS | 457897-92-6 |
| MW: | 433.35 D |
ab 97,00 €
Radiprodil
Artikelnummer: TGM-T5385-100mg
Description: Radiprodil (RGH-896) (RGH-896) is an orally active and selective NMDA NR2B receptors antagonist. It was a potential treatment of neuropathic pain associated with diabetic peripheral neuropathy (DPNP). Target: NMDAR, iGluR. Smiles: Fc1ccc(CC2CCN(CC2)C(=O)C(=O)Nc2ccc3[nH]c(=O)oc3c2)cc1. References: Labas...
| Schlagworte: | RGH-896 |
| Anwendung: | NR2B subunit-containing NMDA receptor antagonist |
| CAS | 496054-87-6 |
| MW: | 397.4 D |
ab 42,00 €
NMDA
Artikelnummer: TGM-T6608-100mg
Description: N-Methyl-D-aspartic acid is an amino acid that, as the D-isomer, is the defining agonist for the NMDA (N-Methyl-D-aspartic acid) receptor subtype of glutamate receptors. Target: NMDAR, Endogenous Metabolite, iGluR. Smiles: CN[C@H](CC(O)=O)C(O)=O. References: Cull-Candy S, et al. Curr Opin Neurobiol,...
| Schlagworte: | N-Methyl-D-aspartic acid |
| Anwendung: | NMDA receptor agonist |
| CAS | 6384-92-5 |
| MW: | 147.13 D |
ab 37,00 €
Eliprodil
Artikelnummer: TGM-T1751-100mg
Description: Eliprodil (SL-820715)(SL-820715), a non-competitive NR2B-NMDA receptor antagonist(IC50: 1 uM), less effective for NR2A- and NR2C-containing receptors(IC50> 100 uM). It has been used in trials studying the treatment of Parkinson Disease and Movement Disorders. Target: iGluR, NMDAR. Smiles:...
| Schlagworte: | SL-820715 |
| Anwendung: | Selective NMDA glutamate receptor NR2B antagonist |
| CAS | 119431-25-3 |
| MW: | 347.85 D |
ab 30,00 €
(-)-Dizocilpine maleate
Artikelnummer: TGM-T6352-100mg
Description: (-)-Dizocilpine maleate ((-)-MK 801 (Maleate)) is a potent, selective, and non-competitive NMDA receptor antagonist, with a Kd of 37.2 nM in rat brain membranes. Target: NMDAR, iGluR. Smiles: OC(=O)\C=C/C(O)=O.C[C@@]12N[C@@H](Cc3ccccc13)c1ccccc21. References: Wong EH, et al. Proc Natl Acad Sci U S A,...
| Schlagworte: | (-)-MK 801 (Maleate), C13737, (-)-MK 801 Maleate |
| Anwendung: | NMDA receptor antagonist |
| CAS | 121917-57-5 |
| MW: | 337.37 D |
ab 45,00 €