Zu "K05209" wurden 82 Artikel gefunden!
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D-AP5
Artikelnummer: Cay14539-10
D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist (Kd = 1.4 µM) that competitively inhibits the glutamate binding site of NMDA receptors. Whereas D-AP5 is the active (-)-stereoisomer, its (+)-isomer (L-AP5) demonstrates considerably less potent NMDA receptor antagonist activity. AP5 has been...
| Schlagworte: | D-2-Amino-5-Phosphonovaleric Acid, D-APV, 5-phosphono-D-norvaline |
| Anwendung: | NMDA receptor antagonist |
| CAS | 79055-68-8 |
| MW: | 197.1 D |
ab 78,00 €
(RS)-(Tetrazol-5-yl)glycine
Artikelnummer: TGM-T16801-100mg
Description: (RS)-(Tetrazol-5-yl)glycine (LY 285265) [(D,L-(tetrazol-5-yl)glycine] is an effective and selective N-methyl-D-aspartate receptor agonist with EC50s of 99 nM for GluN1/GluN2D and 1.7 µM for GluN1/GluN2A. Target: NMDAR, iGluR. Smiles: NC(C(O)=O)c1nn[nH]n1. References: Schoepp DD, et al....
| Schlagworte: | D,L-(tetrazol-5-yl)glycine, LY 285265 |
| Anwendung: | NMDA receptor agonist |
| CAS | 138199-51-6 |
| MW: | 143.1 D |
ab 37,00 €
Rapastinel
Artikelnummer: TGM-T3407-10mg
Description: Rapastinel (TPPT-amide) (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator. Target: NMDAR, iGluR. Smiles: C[C@@H](O)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(N)=O. References: Burgdorf J, et al. Neuroscience. 2015 Nov 12,308:202-11.
| Schlagworte: | GLYX-13, Thr-Pro-Pro-Thr-NH2, TPPT-amide |
| Anwendung: | NMDAR modulator |
| CAS | 117928-94-6 |
| MW: | 413.47 D |
ab 42,00 €
TCN 201
Artikelnummer: TGM-T7870-100mg
Description: TCN 201 is a selective antagonist of NMDA receptors containing the NR2A subunit. Target: iGluR, NMDAR. Smiles: Fc1ccc(cc1Cl)S(=O)(=O)NCc1ccc(cc1)C(=O)NNC(=O)c1ccccc1. References: Hansen K B , Ogden K K , Traynelis S . Subunit-selective allosteric inhibition of glycine binding to NMDA receptors[J]....
| Schlagworte: | TCN-201 |
| Anwendung: | NMDA receptor (NR2A) antagonist |
| CAS | 852918-02-6 |
| MW: | 461.89 D |
ab 60,00 €
L-701324
Artikelnummer: TGM-T1909-100mg
Description: L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant. Target: NMDAR, iGluR. Smiles: Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12. References: Wlaz P, Poleszak E. Pharmacol Rep. 2011,63(5):1231-4.
| Schlagworte: | L701324 |
| Anwendung: | NMDA receptor antagonist |
| CAS | 142326-59-8 |
| MW: | 363.79 D |
ab 34,00 €
Glutamate receptor ionotropic, NMDA 2A (GRIN2A),partial,...
Artikelnummer: CSB-EP618634HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 23-555aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: VYQRAVMAVG SLTINEERSE VVDFSVPFVE TGISVMVSRS NGTVSPSAFL IGKAIWLLWG LVFNNSVPVQ NPKGTTSKIM MHQYMTKFNQ KGVEDALVSL KTGKLDAFIY DAAVLNYKAG RDEGCKLVTI. Purity:...
| Schlagworte: | NR2A, hNR2A, GRIN2A, GluN2A, NMDAR2A, Glutamate receptor ionotropic, NMDA 2A, N-methyl D-aspartate receptor subtype 2A,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 18.2 kD |
ab 219,00 €
Anti-GRIN2A
Artikelnummer: CSB-PA14129A0Rb.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: GRIN2A. Antigen Species: Human
| Schlagworte: | Anti-NR2A, Anti-hNR2A, Anti-GRIN2A, Anti-GluN2A, Anti-NMDAR2A, Anti-Glutamate receptor ionotropic, NMDA 2A, Anti-N-methyl... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-GRIN2A
Artikelnummer: CSB-PA240091.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GRIN2A. Antigen Species: Human
| Schlagworte: | Anti-NR2A, Anti-hNR2A, Anti-GRIN2A, Anti-GluN2A, Anti-NMDAR2A, Anti-Glutamate receptor ionotropic, NMDA 2A, Anti-N-methyl... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-GRIN2A
Artikelnummer: CSB-PA545861.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GRIN2A. Antigen Species: Human
| Schlagworte: | Anti-NR2A, Anti-hNR2A, Anti-GRIN2A, Anti-GluN2A, Anti-NMDAR2A, Anti-Glutamate receptor ionotropic, NMDA 2A, Anti-N-methyl... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
NMDA
Artikelnummer: Cay14581-50
NMDA is a synthetic amino acid derivative that acts as a specific agonist at the NMDA receptor, mimicking the excitatory action of the endogenous ligand glutamate. Signaling through the NMDA receptor influences both neuronal plasticity and neurotoxicity. Repetitive activation of NMDA synapses leads to long-term...
| Schlagworte: | N-Methyl-D-Aspartic Acid, N-methyl-D-aspartic acid |
| Anwendung: | NMDA receptor agonist |
| CAS | 6384-92-5 |
| MW: | 147.1 D |
ab 83,00 €
Memantine (hydrochloride)
Artikelnummer: Cay14184-100
Memantine is an NMDA receptor antagonist that blocks NMDA-induced currents in rat retinal ganglion cells by 90% when used at a concentration of 12 µM. It reverses inhibition of dephosphorylation of the synthetic tau phosphopeptide p17 (tau194-207) induced by the endogenous inhibitor of protein phosphatase 2A (PP2A)...
| Schlagworte: | Akatinol, Axura, Ebix, Namenda, NSC 102290, SUN Y7017, 3,5-dimethyl-tricyclo[3.3.1.13,7]decan-1-amine, monohydrochloride |
| Anwendung: | NMDA open-channel blocker |
| CAS | 41100-52-1 |
| MW: | 215.8 D |
ab 36,00 €
1-Aminocyclopropanecarboxylic Acid
Artikelnummer: Cay16132-100
1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on...
| Schlagworte: | ACC, ACPC, NSC 98430, 1-amino-cyclopropanecarboxylic acid |
| Anwendung: | Plant hormone precursor, NMDA receptor agonist |
| CAS | 22059-21-8 |
| MW: | 101.1 D |
ab 44,00 €