Zu "K05185" wurden 23 Artikel gefunden!
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Anti-GABRE
Artikelnummer: CSB-PA004692.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-GABRE, Anti-GABA(A) receptor subunit epsilon, Anti-Gamma-aminobutyric acid receptor subunit epsilon, GABA(A) receptor... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 106,00 €
Bretazenil
Artikelnummer: Cay28411-5
Bretazenil is a positive allosteric modulator of GABAA receptors with anticonvulsant and anxiolytic activity. It potentiates GABA-gated chloride currents in rat cortical neurons and in HEK293 cells expressing alpha1beta1gamma2 subunit-containing GABAA receptors (EC50s = 60 and 10 nM, respectively). Bretazenil...
| Schlagworte: | Ro 16-6028, (13aS)-8-bromo-11,12,13,13a-tetrahydro-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic... |
| Anwendung: | GABA-A receptor positive allosteric modulator |
| CAS | 84379-13-5 |
| MW: | 418.3 D |
ab 50,00 €
3beta,5alpha-THDOC
Artikelnummer: Cay18431-5
3beta,5alpha-THDOC is a neurosteroid. It inhibits seizures induced by pilocarpine, but not pentylenetetrazol (PTZ, Cay-18682), in mice (ED50s = 45.9 and >100 mg/kg, respectively). 3beta,5alpha-THDOC has been found in the urine of women during the third trimester of pregnancy.Formal Name:...
| Schlagworte: | 3beta,21-dihydroxy-5alpha-Pregnan-20-one, 3beta,5alpha-Tetrahydrodeoxycorticosterone, 3beta,5alpha-Tetrahydroprogesterone,... |
| Anwendung: | GABAA receptor modulator control |
| CAS | 567-01-1 |
| MW: | 334.5 D |
ab 43,00 €
Chlormethiazole (hydrochloride)
Artikelnummer: Cay33437-5
Chlormethiazole is a potentiator of GABAA receptors. It potentiates GABA-induced currents in L-M(TK-) cells expressing alpha1beta1gamma2 or alpha1beta2gamma2 subunit-containing GABAA receptors with EC50 values of 0.8 and 3.4 µM, respectively. Chlormethiazole protects against seizures induced by maximal electroshock...
| Schlagworte: | Clomethiazole, 5-(2-chloroethyl)-4-methyl-thiazole, monohydrochloride |
| Anwendung: | GABAA receptors potentiator |
| CAS | 6001-74-7 |
| MW: | 198.1 D |
ab 50,00 €
6-(4-Methoxyphenyl)-3-pyridazinamine
Artikelnummer: Cay17588-50
Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influence on target neurons. These receptors are the major targets for benzodiazepines and related anxiolytic drugs. 6-(4-Methoxyphenyl)-3-pyridazinamine is an...
| Schlagworte: | 6-(4-methoxyphenyl)-3-pyridazinamine |
| Anwendung: | GABAA receptor antagonist |
| CAS | 4776-87-8 |
| MW: | 201.2 D |
ab 84,00 €
Ganaxolone
Artikelnummer: Cay20919-5
Ganaxolone (Cay-20919) is an analytical reference standard categorized as a GABAA receptor positive allosteric modulator. Ganaxolone has anticonvulsant activity in mice. Ganaxolone is regulated as a Schedule V compound in the United States. This product is intended for research and forensic applications.Formal Name:...
| Schlagworte: | CCD 1042, (3alpha,5alpha)-3-hydroxy-3-methyl-pregnan-20-one |
| Anwendung: | Allopregnanolone analog |
| CAS | 38398-32-2 |
| MW: | 332.5 D |
ab 43,00 €
Etifoxine
Artikelnummer: Cay15999-50
Etifoxine is a positive allosteric modulator of alpha1beta2gamma2 and alpha1beta3gamma2 subunit-containing GABAA receptors. It selectively increases GABA-induced currents in X. laevis oocytes expressing alpha1beta2gamma2 or alpha1beta3gamma2 over alpha1beta1gamma2 subunit-containing receptors at 20 µM. Etifoxine...
| Schlagworte: | Etafenoxine, HOE 36-801, 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3, 1-benzoxazin-2-amine |
| Anwendung: | Anxiolytic, Positive allosteric GABA(A) receptor modulator |
| CAS | 21715-46-8 |
| MW: | 300.8 D |
ab 115,00 €
Alpidem
Artikelnummer: Cay34252-5
Alpidem is an anxiolytic agent. It selectively binds to alpha1beta2gamma2 subunit-containing GABAA receptors over alpha5beta2gamma2 subunit-containing GABAA receptors in HEK293 cells (IC50s = 0.017 and >10 µM, respectively, for the recombinant rat receptors). Alpidem also binds to the GABAA/benzodiazepine receptor...
| Schlagworte: | 6-chloro-2-(4-chlorophenyl)-N,N-dipropyl-imidazo[1,2-a]pyridine-3-acetamide |
| Anwendung: | Anxiolytic agent, GABA-A receptor agonist |
| CAS | 82626-01-5 |
| MW: | 404.3 D |
ab 84,00 €
Anti-GABRE
Artikelnummer: ATA-HPA045918.100
Protein function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative....
| Schlagworte: | Anti-GABRE, Anti-GABA(A) receptor subunit epsilon, Anti-Gamma-aminobutyric acid receptor subunit epsilon |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 335,00 €
GABRE (Vector pUC, Accession No. BC059376)
Artikelnummer: CSB-CL009150HU.10
Length: 1098 Sequence: atgttgtcga aagttcttcc agtcttccta ggcatcttat tgatcctcca gtcgagggtc gagggacctc agactgaatc aaagaatgaa gcctcttccc gtgatgttgt ctatggcccc cagccccagc ctctggaaaa tcagctcctc tctgaggaaa caaagtcaac tgagactgag actgggagca gagttggcaa actgccagaa gcctctcgca tcctgaacac tatcctgagt aattatgacc acaaactgcg...
| Schlagworte: | GABRE, GABA(A) receptor subunit epsilon, Gamma-aminobutyric acid receptor subunit epsilon |
| Anwendung: | Molecular biology, clone |
| Spezies-Reaktivität: | human |
398,00 €
Anti-GABAA Repsilon
Artikelnummer: ELK-ES3798.100
The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is...
| Schlagworte: | Anti-GABRE, Anti-GABA(A) receptor subunit epsilon, Anti-Gamma-aminobutyric acid receptor subunit epsilon, GABAA Repsilon... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse, |
ab 169,00 €
GABRE, Human gamma-aminobutyric acid (GABA) A receptor,...
Artikelnummer: VHPS-3497
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | GABRE, GABA(A) receptor subunit epsilon, Gamma-aminobutyric acid receptor subunit epsilon |
| Anwendung: | RNA quantification |
43,00 €