Zu "K05175" wurden 174 Artikel gefunden!
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Etomidate (CRM)
Artikelnummer: Cay41826-1
Etomidate (CRM) (Cay-41826) is a certified reference material categorized as an anesthetic. Etomidate has been associated with overdose and death. Formulations containing etomidate have been used as anesthetics.This product is intended for research and forensic applications.Formal Name:...
| Schlagworte: | (+)-Etomidate, (R)-Etomidate, d-Etomidate, R 16659, 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylic acid ethyl ester |
| Anwendung: | Certified reference material, anesthetic |
| CAS | 33125-97-2 |
| MW: | 244.3 D |
180,00 €
Clomethiazole
Artikelnummer: TGM-T14983-100mg
Description: Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlormethiazole inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes. Target: GABA Receptor, P450. Smiles:...
| Schlagworte: | 5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE, Chlormethiazole, Distraneurin |
| Anwendung: | Targets gamma-aminobutyric acid receptor subunit alpha (GABRA) |
| CAS | 533-45-9 |
| MW: | 161.65 D |
ab 41,00 €
NS11394
Artikelnummer: TGM-T2067-1mg
Description: NS11394 is a effective and subtype-selective GABA(A) receptor-positive modulator, possesses a functional efficacy selectivity profile of alpha(5) > alpha(3) > alpha(2) > alpha(1) at GABA(A) alpha subunit-containing receptors. Target: GABA Receptor. Smiles: CC(C)(O)c1ccc2n(cnc2c1)-c1cccc(c1)-c1ccccc1C#N....
| Schlagworte: | NS 11394 |
| Anwendung: | GABA(A) receptor positive allosteric modulator |
| CAS | 951650-22-9 |
| MW: | 353.42 D |
ab 33,00 €
Thiomuscimol hydrobromide
Artikelnummer: TGM-T28965-10mg
Description: Thiomuscimol hydrobromide is an agonist of GABAA receptor. Target: Others. Smiles: C(N)C1=CC(=O)NS1
| Anwendung: | GABA(A) receptor agonist |
| CAS | 62020-54-6 |
| MW: | 130.17 D |
ab 151,00 €
Chlormethiazole edisylate
Artikelnummer: TGM-T27007-25mg
Description: Chlormethiazole edisylate is a positive allosteric modulator of the GABAA receptor. Chlormethiazole edisylate is a sedative and hypnotic. Target: Others. Smiles: O=S(=O)(O)CCS(=O)(=O)O.ClCCC=1SC=NC1C. References: Harenko A. A comparison between chlormethiazole and nitrazepam as hypnotics in...
| Schlagworte: | Clomethiazole ethanedisulfonate, Heminevrin, Clomethiazole edisylate, Hemithiamine, Distraneurin |
| Anwendung: | Targets gamma-aminobutyric acid receptor subunit alpha (GABRA) |
| CAS | 1867-58-9 |
| MW: | 351.85 D |
ab 1.491,00 €
AZD7325
Artikelnummer: TGM-T7699-100mg
Description: AZD7325 (AZD-7325) is a GABA-Aalpha2,3 -selective receptor modulator. Target: GABA Receptor, P450. Smiles: CCCNC(=O)c1nnc2c(cccc2c1N)-c1c(F)cccc1OC. References: ProfileToshihiro Nomura, et al. Potentiating alpha2 subunit containing perisomatic GABAA receptors protects against seizures in a mouse model...
| Schlagworte: | AZD-7325 |
| Anwendung: | Alpha2- / alpha3 subunit-containing GABAA receptor positive allosteric modulator |
| CAS | 942437-37-8 |
| MW: | 354.38 D |
ab 63,00 €
Avermectin B1a
Artikelnummer: TGM-T7605-100mg
Description: Avermectin B1a is a macrocyclic lactone disaccharide anthelmintic agent . Target: Parasite, Antibiotic. Smiles:...
| Schlagworte: | Avamectin B1a, Abamectin B1a |
| Anwendung: | Anthelmintic agent |
| CAS | 65195-55-3 |
| MW: | 873.08 D |
ab 30,00 €
6-(4-Methoxyphenyl)-3-pyridazinamine
Artikelnummer: TGM-T7793-100mg
Description: 6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonist. Target: GABA Receptor. Smiles: COC1=CC=C(C=C1)C1=CC=C(N)N=N1. References: Wermuth C G , Bourguignon J J , Schlewer G , et al. ChemInform Abstract: Synthesis and Structure-Activity Relationships of a Series of Aminopyridazine...
| Anwendung: | GABAA receptor antagonist |
| CAS | 4776-87-8 |
| MW: | 201.22 D |
ab 43,00 €
GABRA1 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01366-100ug
Description: GABRA1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.9 kDa and the accession number is P14867.
| Schlagworte: | GABRA1, GABA(A) receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit alpha-1 |
| MW: | 29.9 kD |
ab 352,00 €
L-655708
Artikelnummer: TGM-TQ0151-10mg
Description: L-655708 is a selective and highly potent GABAA receptor reverse agonist with a Ki value of 0.45 nM. Target: GABA Receptor. Smiles: [H][C@@]12CCCN1C(=O)c1cc(OC)ccc1-n1cnc(C(=O)OCC)c21. References: Saab BJ, et al. Short-term memory impairment after isoflurane in mice is prevented by the alpha5...
| Anwendung: | Nootropic GABA(A) receptor subunit alpha-5 ligand |
| CAS | 130477-52-0 |
| MW: | 341.36 D |
ab 76,00 €
Lorediplon
Artikelnummer: TGM-TQ0023-100mg
Description: Lorediplon is a novel hypnotic drug acting as a GABAA receptor modulator, differentially active at the alpha1-subunit, associated with promoting sleep. Target: GABA Receptor. Smiles: CN(C(C)=O)c1cc(ccc1F)-c1ccnc2c(cnn12)C(=O)c1cccs1. References: Horoszok L, et al. A single-dose, randomized,...
| Anwendung: | GABRA1 ligand |
| CAS | 917393-39-6 |
| MW: | 394.42 D |
ab 39,00 €
ONO-8590580
Artikelnummer: TGM-TQ0040-100mg
Description: ONO-8590580 (CS-2894) is a negative allosteric modulator of GABAA alpha5. Target: GABA Receptor. Smiles: Cc1c(F)c(Nc2ccc(cn2)-c2cn(C)cn2)cc2n(CC3CC3)cnc12. References: Kawaharada S, et al. ONO-8590580, a Novel GABAAalpha5 Negative Allosteric Modulator Enhances Long-Term Potentiation and Improves...
| Schlagworte: | CS-2894 |
| Anwendung: | Alpha5 subunit-containing GABAA receptor (benzodiazepine binding site) negative allosteric modulator |
| CAS | 1802661-73-9 |
| MW: | 376.43 D |
ab 59,00 €