Zu "K05115" wurden 124 Artikel gefunden!
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Dubermatinib
Artikelnummer: TGM-T2005-1mg
Description: Dubermatinib (TP0903) is a potent and selective Axl kinase inhibitor. Target: Apoptosis, TAM Receptor. Smiles: CN(C)S(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(CN3CCN(C)CC3)cc2)ncc1Cl. References: Mollard A, et al. ACS Med Chem Lett. 2011, 2(12), 907-912.
| Schlagworte: | TP0903 |
| Anwendung: | Targets AXL receptor tyrosine kinase [EC:2.7.10.1] (AXL, UFO) |
| CAS | 1341200-45-0 |
| MW: | 516.06 D |
ab 31,00 €
Bemcentinib
Artikelnummer: TGM-T6269-100mg
Description: Bemcentinib (R428) is a selective inhibitor of Axl (IC50: 14 nM) and has been investigated for the treatment of NSCLC. Target: TAM Receptor. Smiles: Nc1nc(Nc2ccc3CC[C@@H](CCc3c2)N2CCCC2)nn1-c1cc2CCCc3ccccc3-c2nn1. References: Holland SJ, et al. R428, a selective small molecule inhibitor of Axl kinase,...
| Schlagworte: | R428, BGB324 |
| Anwendung: | Targets AXL receptor tyrosine kinase [EC:2.7.10.1] (AXL, UFO) |
| CAS | 1037624-75-1 |
| MW: | 506.64 D |
ab 34,00 €
SGI-7079
Artikelnummer: TGM-T6982-100mg
Description: SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is also a potential therapeutic target for EGFR inhibitor resistance. Target: FLT, c-RET, c-Met/HGFR, Src, TAM Receptor. Smiles:...
| Anwendung: | Axl inhibitor |
| CAS | 1239875-86-5 |
| MW: | 455.53 D |
ab 35,00 €
AXL Protein, Mouse, Recombinant (hFc)
Artikelnummer: TGM-TMPJ-00399-10ug
Description: AXL Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is Q00993.
| Schlagworte: | Tyrosine-protein kinase receptor UFO, UFO, AXL oncogene |
| MW: | 120 kD |
ab 115,00 €
AXL Protein, Mouse, Recombinant (His & hFc)
Artikelnummer: TGM-TMPY-01021-100ug
Description: AXL Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 74.5 kDa and the accession number is Q00993.
| Schlagworte: | Ark, Ufo, Tyro7, AI323647, AXL receptor tyrosine kinase |
| MW: | 74.5 kD |
587,00 €
AXL Protein, Human, Recombinant (His & Avi)
Artikelnummer: TGM-TMPK-00407-100ug
Description: Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to...
| Schlagworte: | EC 2.7.10, ARK, EC 2.7.10.1, Axl, AXL oncogene, Tyro7, UFO, AI323647, JTK11 |
| MW: | 48.7 kD |
ab 202,00 €
AXL Protein, Human, Recombinant (His & Avi), Biotinylated
Artikelnummer: TGM-TMPK-00408-100ug
Description: Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to...
| Schlagworte: | JTK11, ARK, EC 2.7.10.1, AXL oncogene, Axl, AI323647, EC 2.7.10, UFO, Tyro7 |
| MW: | 48.7 kD |
ab 798,00 €
AXL Protein (Primary Amine Labeling), Human, Recombinant...
Artikelnummer: TGM-TMPK-00410-100ug
Description: Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to...
| Schlagworte: | AI323647, Tyro7, UFO, AXL oncogene, JTK11, Axl, EC 2.7.10.1, ARK, EC 2.7.10 |
| MW: | 72.6 kD |
ab 798,00 €
AXL Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPY-01364-100ug
Description: AXL Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.8 kDa and the accession number is Q00993.
| Schlagworte: | AXL receptor tyrosine kinase, Ufo, Tyro7, AI323647, Ark |
| MW: | 47.8 kD |
587,00 €
Ningetinib
Artikelnummer: TGM-TQ0021-100mg
Description: Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively. Target: c-Met/HGFR, TAM Receptor, VEGFR. Smiles: Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(OCC(C)(C)O)ccc34)c(F)c2)c(=O)n(-c2ccccc2)n1C. References: Ning...
| Schlagworte: | CT053PTSA, CT-053 |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 1394820-69-9 |
| MW: | 556.58 D |
ab 42,00 €
Anti-Axl (Capture/Detector)
Artikelnummer: E-AN002400P.1
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the...
| Schlagworte: | Anti-UFO, Anti-AXL, Anti-AXL oncogene, Anti-Tyrosine-protein kinase receptor UFO, Axl Polyclonal Antibody(Capture/Detector) |
| Anwendung: | ELISA Capture/Detector |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 129,00 €
AXL/UFO Protein ( His Tag) (recombinant human)
Artikelnummer: E-PDMH100272.100
Sequence: Ala26A-Trp451. Fusion tag: C-His Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method Observed Molecular Mass: 60-80 kDa. Protein function: Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and...
| Schlagworte: | AXL, UFO, AXL oncogene, Tyrosine-protein kinase receptor UFO, Recombinant Human AXL/UFO Protein( His Tag) |
| Exprimiert in: | Mammalian |
| Ursprungsart: | human |
ab 248,00 €