Zu "K05096" wurden 172 Artikel gefunden!
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AAL-993
Artikelnummer: TGM-T21593-100mg
Description: AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. AAL993 has a weak inhibitory effect on other tyrosine kinases. AAL993 also shows potent antiangiogenic and antitumor activities. Target: VEGFR. Smiles:...
| Anwendung: | VEGF receptor inhibitor |
| CAS | 269390-77-4 |
| MW: | 371.36 D |
ab 38,00 €
Sitravatinib
Artikelnummer: TGM-T4349-100mg
Description: Sitravatinib (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRalpha/beta, PDGFR, and Axl. Target: VEGFR, Trk receptor, TAM Receptor, c-Kit, Ephrin Receptor, FLT, Discoidin Domain Receptor (DDR). Smiles:...
| Schlagworte: | MG516, MGCD516 |
| Anwendung: | Targets AXL receptor tyrosine kinase [EC:2.7.10.1] (AXL, UFO) |
| CAS | 1123837-84-2 |
| MW: | 629.68 D |
ab 47,00 €
AG-13958
Artikelnummer: TGM-T7493-100mg
Description: AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration. Target: VEGFR. Smiles: Cc1cnn(C)c1C(=O)Nc1cc(Nc2ccc3c(\C=C\c4ccccn4)n[nH]c3c2)ccc1F. References: Barakat M R , Kaiser P . VEGF inhibitors for the treatment of neovascular...
| Schlagworte: | AG-013958 |
| Anwendung: | FLT/TYK receptor inhibitor |
| CAS | 319460-94-1 |
| MW: | 467.5 D |
ab 96,00 €
ODM-203
Artikelnummer: TGM-T7611-100mg
Description: ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity. Target: VEGFR, FGFR. Smiles: Cn1cc(cn1)-c1ccc2n(cnc2c1)-c1cc(NS(=O)(=O)C2CC2)cc(c1)-c1ccc(F)cc1F. References: Tim H Holmström , Anu-Maarit Moilanen , Tarja Ikonen,et al.ODM-203, a...
| Anwendung: | VEGFR / FGFR dual inhibitor |
| CAS | 1430723-35-5 |
| MW: | 505.54 D |
ab 36,00 €
Icrucumab
Artikelnummer: TGM-T76866-10mg
Description: Icrucumab ( IMC-18F1) is a humanized IgG1 monoclonal antibody targeting vascular endothelial growth factor receptor-1.Icrucumab has antitumor activity.Icrucumab has been studied in metastatic colon cancer. Target: VEGFR. References: LoRusso PM, et al. Icrucumab, a fully human monoclonal antibody against...
| Schlagworte: | LY 3012212, IMC-18F1 |
ab 220,00 €
SU14813
Artikelnummer: TGM-T7945-100mg
Description: SU14813 is a multi-receptor tyrosine kinase inhibitor with potent antiangiogenesis and antitumor activity (IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRbeta and KIT). Target: c-Kit, VEGFR, PDGFR. Smiles: Cc1[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NCC(O)CN1CCOCC1. References: Patyna S, et al....
| Anwendung: | Dual VEGFR / PDGFR family kinase inhibitor |
| CAS | 627908-92-3 |
| MW: | 442.48 D |
ab 47,00 €
Lenvatinib mesylate
Artikelnummer: TGM-T8541-100mg
Description: Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities. Target: FGFR, c-Kit, VEGFR, PDGFR, c-RET. Smiles: CS(O)(=O)=O.COc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O. References: Suyama K, et al....
| Schlagworte: | E7080 (mesylate) |
| Anwendung: | Targets FMS-like tyrosine kinase 1 [EC:2.7.10.1] (FLT1, VEGFR1) |
| CAS | 857890-39-2 |
| MW: | 522.96 D |
ab 34,00 €
VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
Artikelnummer: TGM-TMPJ-00412-10ug
Description: Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney,...
| Schlagworte: | Tyrosine-protein kinase receptor FLT, VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Vascular... |
| MW: | 190 kD |
ab 70,00 €
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi)
Artikelnummer: TGM-TMPK-00450-100ug
Description: VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 85.1 kDa and the accession number is P17948-1.
| Schlagworte: | FLT1, Flt-1, FRT, FLT, VEGF R1, VEGFR1 |
| MW: | 85.1 kD |
ab 409,00 €
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi),...
Artikelnummer: TGM-TMPK-00451-100ug
Description: VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 85.1 kDa and the accession number is P17948-1.
| Schlagworte: | VEGF R1, FLT1, Flt-1, FLT, VEGFR1, FRT |
| MW: | 85.1 kD |
ab 798,00 €
FLT1 Protein, Human, Recombinant (hFc)
Artikelnummer: TGM-TMPY-00119-500ug
Description: FLT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is P17948-4.
| Schlagworte: | VEGFR1, VEGFR-1, FLT, FLT-1, fms-related tyrosine kinase 1 |
| MW: | 61.1 kD |
ab 389,00 €
FLT1 Protein, Human, Recombinant (aa 1-328, His)
Artikelnummer: TGM-TMPY-00637-100ug
Description: FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.6 kDa and the accession number is L7RSL3.
| Schlagworte: | VEGFR1, VEGFR-1, fms-related tyrosine kinase 1, FLT-1, FLT |
| MW: | 35.6 kD |
ab 378,00 €