Zu "K05060" wurden 101 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
LMT-28
Artikelnummer: TGM-T15769-100mg
Description: LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2. Target: IL Receptor. Smiles: CCCCCC(=C)[C@@H](O)[C@H](C)C(=O)N1[C@H](COC1=O)C(C)C. References: Hong SS, et al. A Novel Small-Molecule Inhibitor Targeting the IL-6 Receptor beta Subunit,...
| Anwendung: | gp130 (CD130)-IL6/IL6Ralpha protein-protein interaction inhibitor |
| CAS | 1239600-18-0 |
| MW: | 311.42 D |
ab 32,00 €
SC144 hydrochloride
Artikelnummer: TGM-T41260-2mg
Description: SC144 hydrochloride, a first-in-class, orally active, small-molecule gp130 (IL6-beta) inhibitor, demonstrates potent inhibition of gp130 ligand-triggered signaling. By binding to gp130, it initiates gp130 phosphorylation (S782) and deglycosylation, impedes Stat3 phosphorylation and nuclear...
| Anwendung: | gp130 inhibitor |
| CAS | 917497-70-2 |
| MW: | 358.76 D |
52,00 €
RCGD423
Artikelnummer: TGM-T5359-100mg
Description: RCGD423, a small molecule gp130 modulator, prevents articular cartilage degeneration and promotes repair. Target: Interleukin. Smiles: Brc1ccc(Nc2nc(cs2)-c2ccccc2)cc1. References: Shkhyan R, et al. Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair....
| Anwendung: | gp130 modulator |
| CAS | 108237-91-8 |
| MW: | 331.23 D |
ab 32,00 €
GP130 receptor agonist-1
Artikelnummer: TGM-T9157-100mg
Description: GP130 receptor agonist-1 (N-(4-Fluorophenyl)-4-phenyl-2-thiazolami) is a potent, brain-penetrant and orally active GP130 receptor agonist. Target: Interleukin. Smiles: FC1=CC=C(NC2=NC(=CS2)C2=CC=CC=C2)C=C1. References: Mohammad Parvez Alam,et al. A Small Molecule Mimetic of the Humanin Peptide as a...
| Schlagworte: | N-(4-Fluorophenyl)-4-phenyl-2-thiazolami |
| Anwendung: | Humanin peptide mimetic |
| CAS | 339303-87-6 |
| MW: | 270.32 D |
ab 31,00 €
gp130/IL6ST Protein, Human, Recombinant (His & hFc)
Artikelnummer: TGM-TMPY-01076-100ug
Description: gp130/IL6ST Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 96 kDa and the accession number is P40189-1.
| Schlagworte: | GP130, interleukin 6 signal transducer, IL-6RB, CD130, CDW130 |
| MW: | 96 kD |
ab 187,00 €
gp130/IL6ST Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPK-00412-100ug
Description: gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities...
| Schlagworte: | IL-6R-beta, gp130, CD130, IL6ST, IL-6 R beta, CDw130, IL-6R-beta, IL-6RB, gp130/CD130/IL-6 R beta, IL-6 R beta |
| MW: | 68.94 kD |
ab 363,00 €
gp130/IL6ST Protein, Human, Recombinant (aa 1-618, DDDDK)
Artikelnummer: TGM-TMPY-06039-100ug
Description: gp130/IL6ST Protein, Human, Recombinant (aa 1-618, DDDDK) is expressed in HEK293 mammalian cells. The predicted molecular weight is 68.4 kDa and the accession number is P40189-1.
| Schlagworte: | IL-6RB, CDW130, interleukin 6 signal transducer, CD130, GP130 |
| MW: | 68.4 kD |
ab 686,00 €
gp130/IL6ST Protein, Rat, Recombinant (His)
Artikelnummer: TGM-TMPY-02148-100ug
Description: gp130/IL6ST Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68.2 kDa and the accession number is H9BFG4.
| Schlagworte: | interleukin 6 signal transducer |
| MW: | 68.2 kD |
686,00 €
gp130/IL6ST Protein, Rat, Recombinant (His & mFc)
Artikelnummer: TGM-TMPY-01995-100ug
Description: gp130/IL6ST Protein, Rat, Recombinant (His & mFc) is expressed in HEK293 mammalian cells with His, mFc tag. The predicted molecular weight is 94.3 kDa and the accession number is H9BFG4.
| Schlagworte: | interleukin 6 signal transducer |
| MW: | 94.3 kD |
686,00 €
gp130/IL6ST Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPY-01832-100ug
Description: gp130/IL6ST Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68 kDa and the accession number is Q00560.
| Schlagworte: | BB405851, AA389424, gp130, 5133400A03Rik, interleukin 6 signal transducer, D13Ertd699e, CD130 |
| MW: | 68 kD |
ab 69,00 €
gp130/IL6ST Protein, Rhesus, Recombinant (hFc)
Artikelnummer: TGM-TMPY-03687-1mg
Description: gp130/IL6ST Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 102.6 kDa and the accession number is A0A8J8YAN3.
| Schlagworte: | interleukin 6 signal transducer |
| MW: | 102.6 kD |
ab 886,00 €
gp130/IL6ST Protein, Rhesus, Recombinant (His)
Artikelnummer: TGM-TMPY-03743-1mg
Description: gp130/IL6ST Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.2 kDa and the accession number is A0A8J8YAN3.
| Schlagworte: | interleukin 6 signal transducer |
| MW: | 69.2 kD |
ab 886,00 €