Zu "K05050" wurden 52 Artikel gefunden!
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Reparixin L-lysine salt
Artikelnummer: TGM-T12705-10mg
Description: Reparixin L-lysine salt (Repertaxin L-lysine salt) is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor. Target: CXCR. Smiles: NCCCC[C@H](N)C(O)=O.CC(C)Cc1ccc(cc1)[C@@H](C)C(=O)NS(C)(=O)=O. References: Moriconi A, et al. Design of noncompetitive interleukin-8 inhibitors acting on CXCR1...
| Schlagworte: | Repertaxin L-lysine salt |
| Anwendung: | Noncompetitive allosteric CXCR1 / CXCR2 inhibitor |
| CAS | 266359-93-7 |
| MW: | 429.57 D |
ab 39,00 €
SB-265610
Artikelnummer: TGM-T16850-100mg
Description: SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and 70 nM, respectively). Target: CXCR. Smiles: Brc1ccccc1NC(=O)Nc1ccc(C#N)c2nn[nH]c12....
| Schlagworte: | GSK-CXCR2 |
| Anwendung: | Allosteric, inverse CXCR2 agonist |
| CAS | 211096-49-0 |
| MW: | 357.16 D |
ab 51,00 €
SB-332235
Artikelnummer: TGM-T34544-10mg
Description: SB-332235 is an effective specific CXCR2 antagonist. And it is effectively inhibited CS-induced neutrophilia in a dose-dependent manner. Target: Others. Smiles: N(C(NC1=C(Cl)C(Cl)=CC=C1)=O)C2=C(O)C(S(N)(=O)=O)=C(Cl)C=C2. References: Wang Y, Luo W, Stricker R, Reiser G. Protease-activated receptor-1...
| Schlagworte: | SB 332235, SB332235 |
| Anwendung: | CXCR2 antagonist |
| CAS | 276702-15-9 |
| MW: | 410.66 D |
ab 108,00 €
Antileukinate
Artikelnummer: TGM-T36623-1mg
Description: Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus that inhibits the binding of CXC chemokines to the chemokine receptor CXCR2. It inhibits IL-8 binding to neutrophils (Ki = 2.7-13 µM), prevents neutrophil chemotaxis and beta-glucuronidase...
| Anwendung: | CXCR2 antagonist |
| CAS | 138559-60-1 |
| MW: | 1003.19 D |
ab 287,00 €
AZD-5069
Artikelnummer: TGM-T7681-100mg
Description: AZD-5069 is an chemokine receptor 2 antagonist (CXCR2, IC50 = 0.79 nM). Target: CXCR. Smiles: C[C@@H](Oc1cc(NS(=O)(=O)N2CCC2)nc(SCc2cccc(F)c2F)n1)[C@@H](O)CO. References: Nicholls D J , Wiley K , Dainty I , et al. Pharmacological Characterization of AZD5069, a Slowly Reversible CXC Chemokine Receptor 2...
| Anwendung: | CXCR2 antagonist |
| CAS | 878385-84-3 |
| MW: | 476.52 D |
ab 46,00 €
SB225002
Artikelnummer: TGM-T1955-100mg
Description: SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2. Target: CXCR. Smiles: N(C(NC1=C(Br)C=CC=C1)=O)C2=C(O)C=C(N(=O)=O)C=C2. References: White JR, et al. J Biol Chem. 1998, 273(17), 120095-120098.
| Anwendung: | CXCR2 antagonist |
| CAS | 182498-32-4 |
| MW: | 352.14 D |
ab 43,00 €
C-X-C chemokine receptor type 2 (Cxcr2), mouse, recombinant
Artikelnummer: CSB-CF011673MO.100
Organism: Mus musculus (Mouse). Source: in vitro E.coli expression system. Expression Region: 1-359aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MGEFKVDKFN IEDFFSGDLD IFNYSSGMPS ILPDAVPCHS ENLEINSYAV VVIYVLVTLL SLVGNSLVML VILYNRSTCS VTDVYLLNLA IADLFFALTL PVWAASKVNG...
| Schlagworte: | CD182, Cxcr2, CXCR-2, Cmkar2, CXC-R2, IL-8R B, GRO/MGSA receptor, C-X-C chemokine receptor type 2, High affinity... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli in vitro |
| Ursprungsart: | mouse |
| MW: | 43.2 kD |
ab 1.413,00 €
C-X-C chemokine receptor type 2 (CXCR2), partial, human,...
Artikelnummer: CSB-EP011673HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-40aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MEDFNMESDS FEDFWKGEDL SNYSYSSTLP PFLLDAAPCE. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form:...
| Schlagworte: | CXCR2, CD182, IL8RB, CXCR-2, CXC-R2, CDw128b, IL-8R B, GRO/MGSA receptor, IL-8 receptor type 2, C-X-C chemokine receptor... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 20.6 kD |
ab 283,00 €
Anti-CXCR2 antibody(DMC681), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100681.10
Protein function: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also...
| Schlagworte: | Anti-CD182, Anti-CDw128b, Anti-CMKAR2, Anti-IL8R2, Anti-IL8RA, Anti-IL8RB, Anti-CXCR2 antibody(DMC681), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
| CAS | 12 |
ab 139,00 €
Human CXCR2 Protein, hFc Tag
Artikelnummer: DIM-PME100937.10
Recombinant Human CXCR2 with C-terminal human Fc tag. CXCR2(Met1-Lys48) hFc(Glu99-Ala330), Protein function: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a...
| Schlagworte: | CD182, CDw128b, CMKAR2, IL8R2, IL8RA, IL8RB |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 31.7 kD |
ab 95,00 €
CXCR2 (human) full length protein-synthetic nanodisc
Artikelnummer: DIM-FLP100066.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Schlagworte: | IL8RB, CD182, CXCR2, CXCR-2, CXC-R2, IL-8R B, CDw128b, GRO/MGSA receptor, IL-8 receptor type 2, C-X-C chemokine receptor... |
| Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 40.8 kD |
ab 1.260,00 €
Anti-CXCR2
Artikelnummer: CSB-PA005633.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CXCR2, Anti-IL8RB, Anti-CD182, Anti-CXC-R2, Anti-CXCR-2, Anti-CDw128b, Anti-IL-8R B, Anti-GRO/MGSA receptor,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 106,00 €