Zu "K05050" wurden 46 Artikel gefunden!
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NEU
C-X-C chemokine receptor type 2 (Cxcr2), mouse, recombinant
Artikelnummer: CSB-CF011673MO.100
Organism: Mus musculus (Mouse). Source: in vitro E.coli expression system. Expression Region: 1-359aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MGEFKVDKFN IEDFFSGDLD IFNYSSGMPS ILPDAVPCHS ENLEINSYAV VVIYVLVTLL SLVGNSLVML VILYNRSTCS VTDVYLLNLA IADLFFALTL PVWAASKVNG...
| Schlagworte: | CD182, Cxcr2, CXCR-2, Cmkar2, CXC-R2, IL-8R B, GRO/MGSA receptor, C-X-C chemokine receptor type 2, High affinity... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli in vitro |
| Ursprungsart: | mouse |
| MW: | 43.2 kD |
ab 1.413,00 €
NEU
C-X-C chemokine receptor type 2 (CXCR2), partial, human,...
Artikelnummer: CSB-EP011673HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-40aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MEDFNMESDS FEDFWKGEDL SNYSYSSTLP PFLLDAAPCE. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form:...
| Schlagworte: | CXCR2, CD182, IL8RB, CXCR-2, CXC-R2, CDw128b, IL-8R B, GRO/MGSA receptor, IL-8 receptor type 2, C-X-C chemokine receptor... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 20.6 kD |
ab 283,00 €
NEU
Anti-CXCR2 antibody(DMC681), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100681.10
Protein function: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also...
| Schlagworte: | Anti-CD182, Anti-CDw128b, Anti-CMKAR2, Anti-IL8R2, Anti-IL8RA, Anti-IL8RB, Anti-CXCR2 antibody(DMC681), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
| CAS | 12 |
ab 139,00 €
NEU
Human CXCR2 Protein, hFc Tag
Artikelnummer: DIM-PME100937.10
Recombinant Human CXCR2 with C-terminal human Fc tag. CXCR2(Met1-Lys48) hFc(Glu99-Ala330), Protein function: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a...
| Schlagworte: | CD182, CDw128b, CMKAR2, IL8R2, IL8RA, IL8RB |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 31.7 kD |
ab 95,00 €
NEU
CXCR2 (human) full length protein-synthetic nanodisc
Artikelnummer: DIM-FLP100066.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Schlagworte: | IL8RB, CD182, CXCR2, CXCR-2, CXC-R2, IL-8R B, CDw128b, GRO/MGSA receptor, IL-8 receptor type 2, C-X-C chemokine receptor... |
| Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 40.8 kD |
ab 1.260,00 €
NEU
Anti-CXCR2
Artikelnummer: CSB-PA005633.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CXCR2, Anti-IL8RB, Anti-CD182, Anti-CXC-R2, Anti-CXCR-2, Anti-CDw128b, Anti-IL-8R B, Anti-GRO/MGSA receptor,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 106,00 €
NEU
Anti-Phospho-CXCR2 (S347)
Artikelnummer: CSB-PA009566.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-CXCR2, Anti-phospho-IL8RB, Anti-phospho-CD182, Anti-phospho-CXC-R2, Anti-phospho-CXCR-2,... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
106,00 €
NEU
Anti-CXCR2
Artikelnummer: CSB-PA282080.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CXCR2. Antigen Species: Human
| Schlagworte: | Anti-CXCR2, Anti-IL8RB, Anti-CD182, Anti-CXC-R2, Anti-CXCR-2, Anti-CDw128b, Anti-IL-8R B, Anti-GRO/MGSA receptor,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
CXCR2-IN-1
Artikelnummer: Cay28426-1
CXCR2-IN-1 is a chemokine (C-X-C motif) receptor 2 (CXCR2) antagonist (IC50 = 0.501 nM in a reporter assay). It inhibits chemotaxis of isolated human neutrophils induced by chemokine (C-X-C motif) ligand 1 (CXCL1, IC50 = 79.4 nM). In vivo, CXCR2-IN-1 (100 mg/kg) inhibits forebrain lesion formation in a mouse model...
| Schlagworte: | CXCR2 Inhibitor 1, N-(2-chloro-3-fluorophenyl)-N'-[4-chloro-2-hydroxy-3-[(1-methyl-4-piperidinyl)sulfonyl]phenyl]-urea |
| Anwendung: | CXCR2 antagonist |
| CAS | 1873376-49-8 |
| MW: | 476.3 D |
ab 88,00 €
SB 225002
Artikelnummer: Cay13336-10
CXCR2 (IL-8RB) is a seven-transmembrane G protein-coupled receptor whose physiological ligands include IL-8 (CXCL8) and growth related oncogene alpha (Gro-alpha, CXCL1). IL-8 and Gro-alpha are pro-inflammatory CXC chemokines that act as chemoattractants, especially for neutrophils, and promote angiogenesis. SB...
| Schlagworte: | N-(2-bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)-urea |
| Anwendung: | CXCR2 antagonist |
| CAS | 182498-32-4 |
| MW: | 352.1 D |
ab 110,00 €
Danirixin
Artikelnummer: Cay20980-25
Danirixin is an antagonist of chemokine (C-X-C motif) receptor 2 (CXCR2, IC50 = 12.5 µM). It is selective for CXCR2 over CXCR1 (IC50 = 977 nM). Danirixin inhibits IL-8-induced calcium mobilization in CHO-K1 cells expressing human CXCR2 (pA2 = 7.52). It inhibits neutrophil surface expression of CD11b in isolated rat...
| Schlagworte: | GSK1325756, GSK1325756B, N-[4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl]-N'-(3-fluoro-2-methylphenyl)-urea |
| Anwendung: | Antiinflammatory, Chemokine (C-X-C motif) receptor 2 antagonist |
| CAS | 954126-98-8 |
| MW: | 441.9 D |
ab 54,00 €
Reparixin (L-Lysine salt)
Artikelnummer: Cay21492-1
Reparixin is a non-competitive allosteric inhibitor of the activation of CXCR1 and CXCR2 chemokine receptors by IL-8 (IC50s = 1 and 100 nM, respectively). It blocks a range of activities related to IL-8 signaling, including leukocyte recruitment (IC50 = 1 nM) and other inflammatory responses, without affecting...
| Schlagworte: | Repertaxin, (alphaR)-alpha-methyl-4-(2-methylpropyl)-N-(methylsulfonyl)benzeneacetamide, L-lysine |
| Anwendung: | Noncompetitive allosteric CXCR1 / CXCR2 inhibitor |
| CAS | 266359-93-7 |
| MW: | 429.6 D |
ab 35,00 €