Zu "K05037" wurden 133 Artikel gefunden!
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Paroxetine (maleate) (CRM)
Artikelnummer: Cay40969-1
Paroxetine (maleate) (CRM) (Cay-40969) is a certified reference material categorized as an antidepressant. Paroxetine decreases immobility time in the forced swim test in mice. Formulations containing paroxetine have been used in the treatment of depression, obsessive-compulsive disorder (OCD), panic disorder,...
| Schlagworte: | (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-piperidine, 2Z-butenedioate |
| Anwendung: | Certified reference material, antidepressant |
| CAS | 64006-44-6 |
| MW: | 445.4 D |
48,00 €
Mesembrine
Artikelnummer: Cay21100-5
Mesembrine is an alkaloid that has been found in S. tortuosum and has serotonin (5-HT) reuptake inhibitory activity. It selectively binds to the 5-HT transporter (SERT, IC50 = 4.3 µg/ml) over a variety of receptors (IC50s = 148->750 µg/ml). Mesembrine inhibits the reuptake of 5-HT in vitro (Ki = 1.4 nM). It has...
| Schlagworte: | (-)-Mesembrine, Mesembranone, (3aS,7aS)-3a-(3,4-dimethoxyphenyl)octahydro-1-methyl-6H-indol-6-one |
| Anwendung: | Bioactive alkaloid, 5-HT reuptake inhibitor |
| CAS | 24880-43-1 |
| MW: | 289.4 D |
ab 208,00 €
Norfluoxetine Hydrochloride
Artikelnummer: TGM-T21029-1mg
Description: Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug. Target: Others. Smiles: Cl.NCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1. References: Shi S, Liu Y, Wu J, Li Z, Zhao Y, Zhong D, Zeng F. Comparative bioavailability and tolerability of a...
| Schlagworte: | Norfluoxetine HCl |
| Anwendung: | Serotonin uptake inhibitor |
| CAS | 57226-68-3 |
| MW: | 331.76 D |
ab 41,00 €
(-)-Mesembrine
Artikelnummer: TGM-T28019-10mg
Description: Mesembrine is a serotonin reuptake inhibitor and is also a weak inhibitor of the enzyme phosphodiesterase 4 (PDE4). Target: Others. Smiles: CN1[C@@]2([C@](CC1)(CCC(=O)C2)C3=CC(OC)=C(OC)C=C3)[H]. References: Krstenansky JL. Mesembrine alkaloids: Review of their occurrence, chemistry, and pharmacology. J...
| Schlagworte: | Mesembrin, Mesembrine, Mesembranone |
| Anwendung: | Bioactive alkaloid, 5-HT reuptake inhibitor |
| CAS | 24880-43-1 |
| MW: | 289.37 D |
ab 375,00 €
Alaproclate (hydrochloride)
Artikelnummer: TGM-T36521-10mg
Description: Alaproclate is a selective serotonin reuptake inhibitor (SSRI).1,2 It inhibits depletion of serotonin (5-HT) induced by 4-methyl-alpha-ethyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus, and striatum (EC50s = 18, 4, 8, and 12 mg/kg, respectively).1 Alaproclate inhibits NMDA-evoked...
| Anwendung: | Selective serotonin reuptake inhibitor (SSRI) |
| CAS | 60719-83-7 |
| MW: | 292.2 D |
ab 164,00 €
meta-Fluoxetine (hydrochloride)
Artikelnummer: TGM-T37474-10mg
Description: meta-Fluoxetine (hydrochloride) can be used in related research in the field of life sciences. Its product number is T37474 and CAS number is 79088-29-2. Target: Others. Smiles: Cl.FC(F)(F)C=1C=CC=C(OC(C=2C=CC=CC2)CCNC)C1
| Anwendung: | Impurity, SSRI |
| CAS | 79088-29-2 |
| MW: | 345.79 D |
ab 164,00 €
Sertraline Free Base
Artikelnummer: TGM-T68683-100mg
Description: Sertraline Free Base is a Selective Serotonin Reuptake Inhibitor (SSRI). It can treat depression, obsessive-compulsive disorder (OCD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), social anxiety disorder, and panic disorder. Target: Others. Smiles:...
| Anwendung: | Targets solute carrier family 6 (neurotransmitter transporter, serotonin) member 4 (SLC6A4, SERT) |
| CAS | 79617-96-2 |
| MW: | 306.23 D |
ab 1.491,00 €
Alaproclate
Artikelnummer: TGM-T69013-10mg
Description: Alaproclate is a non-competitive NMDA receptor antagonist and a new selective 5-HT uptake inhibitor for the study of depression and dementia. Target: NMDAR. Smiles: O=C(OC(C)(C)CC1=CC=C(Cl)C=C1)C(N)C. References: Campagna J, et al. A small molecule ApoE4-targeted therapeutic candidate that normalizes...
| Anwendung: | Targets solute carrier family 6 (neurotransmitter transporter, serotonin) member 4 (SLC6A4, SERT) |
| CAS | 60719-82-6 |
| MW: | 255.74 D |
ab 286,00 €
Norfluoxetine-d5 HCl
Artikelnummer: TGM-T71302-1mg
Description: Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine...
| Anwendung: | GC-MS, LC-MS internal standard, quantification, serotonin uptake inhibitor |
| CAS | 1185132-92-6 |
| MW: | 336.7937 D |
ab 536,00 €
Trimipramine N-oxide
Artikelnummer: TGM-T74582-10mg
Description: Trimipramine N-oxide, an active metabolite of the tricyclic antidepressant trimipramine, effectively inhibits human monoamine transporters for noradrenaline (hNAT), serotonin (hSERT), dopamine (hDAT), and the human organic cation transporters (hOCT1 and hOCT2), with IC50 values of 11.7, 3.59, 9.4, 9.35,...
| Anwendung: | Trimipramine active metabolite |
| CAS | 14171-70-1 |
| MW: | 310.43 D |
ab 264,00 €
Paroxetine
Artikelnummer: TGM-T8708-100mg
Description: Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression. Target: Serotonin Transporter. Smiles: C(OC=1C=C2C(=CC1)OCO2)[C@H]3[C@@H](CCNC3)C4=CC=C(F)C=C4. References: Cipriani A , Furukawa T A , Veronese A , et al. Paroxetine versus other anti-depressive agents for...
| Anwendung: | Targets solute carrier family 6 (neurotransmitter transporter, serotonin) member 4 (SLC6A4, SERT) |
| CAS | 61869-08-7 |
| MW: | 329.37 D |
ab 31,00 €
Sertraline-d3 Hydrochloride
Artikelnummer: TGM-TMID-0307-1mg
Description: Sertraline-d3 Hydrochloride is a deuterated compound of Sertraline Hydrochloride. Sertraline Hydrochloride has a CAS number of 79559-97-0. Sertraline hydrochloride is a selective serotonin uptake inhibitor that is used in the treatment of depression. Smiles:...
| Anwendung: | GC-MS, LC-MS internal standard, quantification, SSRI |
| CAS | 1217741-83-7 |
| MW: | 345.71 D |
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