Zu "K05037" wurden 111 Artikel gefunden!
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Escitalopram (oxalate)
Artikelnummer: Cay39841-1
Escitalopram is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and the (S) isomer of citalopram (Cay-14572) and (R)-citalopram. It selectively binds to SERT (Ki = 0.89 nM) over the norepinephrine and dopamine transporters (Kis = >10,000 and 8,150 nM, respectively) and inhibits 5-HT reuptake in rat brain...
| Schlagworte: | (S)-Citalopram, Lu 26-054-0, (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile,... |
| Anwendung: | Selective serotonin reuptake inhibitor (SSRI) |
| CAS | 219861-08-2 |
| MW: | 414.4 D |
ab 39,00 €
Dapoxetine-d7 (hydrochloride)
Artikelnummer: Cay40762-1
Dapoxetine-d7 is intended for use as an internal standard for the quantification of dapoxetine by GC- or LC-MS. Dapoxetine is a selective serotonin (5-HT) reuptake inhibitor (SSRI, IC50 = 10 nM in isolated rat cerebral cortex membranes). It selectively inhibits 5-HT uptake over norepinephrine or dopamine uptake in...
| Schlagworte: | (S)-(+)-Dapoxetine-d7, Dapoxetine-d7, N,N-dimethyl-alpha3-[2-(1-naphthalenyloxy)ethyl-d7]-benzenemethanamine,... |
| Anwendung: | GC-MS, LC-MS internal standard, quantification, antidepressant, SSRI |
| CAS | 2699607-47-9 |
| MW: | 348.9 D |
266,00 €
Nortriptyline (hydrochloride) (CRM)
Artikelnummer: Cay19042-1
Nortriptyline (hydrochloride) (CRM) (Cay-19042) is a certified reference material categorized as an antidepressant. Nortriptyline is an active metabolite of amitriptyline (Cay-19031, Cay-19029). It decreases immobility time in the forced swim test in rats and has antinociceptive activity in mice. Nortriptyline...
| Schlagworte: | 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, monohydrochloride |
| Anwendung: | Certified reference material categorized, antidepressant, SNRI |
| CAS | 894-71-3 |
| MW: | 299.8 D |
36,00 €
(S)-5-hydroxy-6-methoxy Duloxetine (maleate)
Artikelnummer: Cay39381-1
(S)-5-hydroxy-6-methoxy Duloxetine is an active metabolite of the serotonin (5-HT) and norepinephrine reuptake inhibitor (S)-duloxetine (Cay-14317). It is formed from (S)-duloxetine via a 5- or 6-hydroxy duloxetine intermediate, which is formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2D6, and a catechol...
| Schlagworte: | 2-methoxy-5-[(1S)-3-(methylamino)-1-(2-thienyl)propoxy]-1-naphthalenol, maleate |
| Anwendung: | Active (SNRI) (S)-duloxetine metabolite |
| MW: | 459.5 D |
ab 288,00 €
Fluoxetine (hydrochloride)
Artikelnummer: Cay14418-5
Fluoxetine (hydrochloride) (Cay-14418) is an analytical reference material categorized as an antidepressant. This product is intended for research and forensic applications.Formal Name: N-methyl-gamma-[4-(trifluoromethyl)phenoxy]-benzenepropanamine, monohydrochloride. CAS Number: 56296-78-7. Molecular Formula:...
| Schlagworte: | LY110140, N-methyl-gamma-[4-(trifluoromethyl)phenoxy]-benzenepropanamine, monohydrochloride |
| Anwendung: | Analytical reference material, Antidepressant, Serotonin uptake inhibitor |
| CAS | 56296-78-7 |
| MW: | 345.8 D |
60,00 €
Nortriptyline (hydrochloride)
Artikelnummer: Cay19041-1
Nortriptyline (hydrochloride) (Cay-19041) is an analytical reference material categorized as an antidepressant. Nortriptyline is an active metabolite of amitriptyline (Cay-19031, Cay-19029). It decreases immobility time in the forced swim test in rats and has antinociceptive activity in mice. Nortriptyline decreases...
| Schlagworte: | 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, monohydrochloride |
| Anwendung: | Analytical reference material, antidepressant, serotonin-noradrenaline reuptake inhibitor (SNRI) |
| CAS | 894-71-3 |
| MW: | 299.8 D |
ab 28,00 €
BTS-54-505 (hydrochloride)
Artikelnummer: Cay39828-10
BTS-54-505 is an active metabolite of sibutramine. It inhibits norepinephrine, serotonin (5-HT), and dopamine uptake in rat cortical synaptosomes (IC50s = 0.066, 5.1, and 0.61 µM, respectively). In vivo, BTS-54-505 prevents reserpine-induced ptosis in rats (ED50 = 3.7 mg/kg) and decreases immobility in the Porsolt...
| Schlagworte: | 1-(4-chlorophenyl)-alpha-(2-methylpropyl)-cyclobutanemethanamine, monohydrochloride |
| Anwendung: | Active sibutramine metabolite |
| CAS | 84484-78-6 |
| MW: | 288.3 D |
ab 35,00 €
Fluoxetine hydrochloride
Artikelnummer: LKT-F4780.1
A specific serotonin uptake inhibitor. It was found to exert inhibitory or stimulating effects on T-lymphocyte proliferation depending on the concentration.pH value: 5-7 (5% aqueous solution)
| Schlagworte: | Fluoxetine HCl |
| Anwendung: | Serotonin uptake inhibitor |
| CAS | 59333-67-4 |
| MW: | 345,79 D |
ab 127,00 €
Amitriptyline-d3 (hydrochloride) (CRM)
Artikelnummer: Cay19033-1
Amitriptyline-d3 (hydrochloride) (CRM) (Cay-19033) is intended for use as an internal standard for the quantification of amitriptyline (Cay-19031, Cay-19029) by GC- or LC-MS. Amitriptyline is categorized as a tricyclic antidepressant. This product is intended for research and forensic applications.Formal Name:...
| Schlagworte: | 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-N-(methyl-d3)-1-propanamine, monohydrochloride |
| Anwendung: | Certified reference material, GC-MS, LC-MS internal standard, quantification, tricyclic antidepressant |
| CAS | 342611-00-1 |
| MW: | 316.9 D |
279,00 €
Norfluoxetine (hydrochloride)
Artikelnummer: Cay15900-1
Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15...
| Schlagworte: | Desmethylfluoxetine, gamma-[4-(trifluoromethyl)phenoxy]-benzenepropanamine, monohydrochloride |
| Anwendung: | Serotonin uptake inhibitor |
| CAS | 57226-68-3 |
| MW: | 331.8 D |
ab 61,00 €
Amitriptyline (hydrochloride)
Artikelnummer: Cay15881-5
Amitriptyline is a first generation tricyclic antidepressant. It inhibits serotonin (5-HT) uptake by isolated human platelets by 39 and 68% when used at concentrations of 1 and 4 µg/ml, respectively, and inhibits norepinephrine uptake in rat brain by 77% when administered at a dose of 10 mg/kg. It is also an...
| Schlagworte: | NIH 10794, Ro 4-1575, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine, monohydrochloride |
| Anwendung: | Serotonin / noradrenalin transporter inhibitor |
| CAS | 549-18-8 |
| MW: | 313.9 D |
ab 43,00 €
Imipramine (hydrochloride)
Artikelnummer: Cay15890-1
Imipramine is a first generation tricyclic antidepressant. It inhibits serotonin (5-HT) uptake by isolated human platelets by 54 and 79% when used at concentrations of 1 and 4 µg/ml, respectively, and inhibits norepinephrine uptake in rat brain by 63% when administered at a dose of 20 mg/kg. It also binds to...
| Schlagworte: | Melipramine, Tofranil, 10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine, monohydrochloride |
| Anwendung: | Serotonin transporter inhibitor, noradrenalin transporter inhibitor |
| CAS | 113-52-0 |
| MW: | 316.9 D |
ab 43,00 €