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Zu "K05035" wurden 59 Artikel gefunden!
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Artikelnummer: Cay39381-5
(S)-5-hydroxy-6-methoxy Duloxetine is an active metabolite of the serotonin (5-HT) and norepinephrine reuptake inhibitor (S)-duloxetine (Cay-14317). It is formed from (S)-duloxetine via a 5- or 6-hydroxy duloxetine intermediate, which is formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2D6, and a catechol...
Schlagworte: | 2-methoxy-5-[(1S)-3-(methylamino)-1-(2-thienyl)propoxy]-1-naphthalenol, maleate |
Anwendung: | Active (SNRI) (S)-duloxetine metabolite |
MW: | 459.5 D |
ab 288,00 €
Artikelnummer: Cay39679-10
Viloxazine is an antidepressant. It selectively inhibits norepinephrine uptake over serotonin (5-HT) uptake in rat hypothalamic synaptosomes (IC50s = 0.9 and >100 µM, respectively). Viloxazine (8 and 16 mg/kg) decreases immobility time in the forced swim test in mice. Formulations containing viloxazine have been...
Schlagworte: | ICI 58834, 2-[(2-ethoxyphenoxy)methyl]-morpholine, monohydrochloride |
Anwendung: | Antidepressant, selective noradrenaline reuptake inhibitor (NRI) |
CAS | 35604-67-2 |
MW: | 273.8 D |
ab 39,00 €
Artikelnummer: Cay19041-5
Nortriptyline (hydrochloride) (Cay-19041) is an analytical reference material categorized as an antidepressant. Nortriptyline is an active metabolite of amitriptyline (Cay-19031, Cay-19029). It decreases immobility time in the forced swim test in rats and has antinociceptive activity in mice. Nortriptyline decreases...
Schlagworte: | 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, monohydrochloride |
Anwendung: | Analytical reference material, antidepressant, serotonin-noradrenaline reuptake inhibitor (SNRI) |
CAS | 894-71-3 |
MW: | 299.8 D |
ab 28,00 €
Artikelnummer: ELK-ELK7174.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse NET. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse NET. Next,...
Schlagworte: | NET, Slc6a2, Norepinephrine transporter, Solute carrier family 6 member 2, Sodium-dependent noradrenaline transporter |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: ELK-ELK4774.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human NET. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human NET. Next,...
Schlagworte: | NET, NAT1, SLC6A2, Norepinephrine transporter, Solute carrier family 6 member 2, Sodium-dependent noradrenaline transporter |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay15892-50
Maprotiline is a tricyclic antidepressant. It binds to the norepinephrine transporter (NET, Kd = 11 nM) and is selective for NET over the serotonin (5-HT) and dopamine transporters (Kds = 5,800 and 1,000 nM, respectively). Maprotiline also binds to the 5-HT receptor subtype 5-HT2A (KI = 51 nM), as well as histamine...
Schlagworte: | Ba 34276, N-methyl-9,10-ethanoanthracene-9(10H)-propanamine, monohydrochloride |
Anwendung: | Noradrenalin reuptake inhibitor |
CAS | 10347-81-6 |
MW: | 313.9 D |
ab 50,00 €
Artikelnummer: Cay32702-1
Maprotiline (Cay-32702) is an analytical reference material categorized as a tricyclic antidepressant. Formulations containing maprotiline have been associated with overdoses. This product is intended for use in analytical forensic applications. This product is also available as a general research tool...
Schlagworte: | Ba 34276, N-methyl-9,10-ethanoanthracene-9(10H)-propanamine, monohydrochloride |
Anwendung: | Analytical Reference Material, noradrenalin reuptake inhibitor |
CAS | 10347-81-6 |
MW: | 313.9 D |
ab 43,00 €
Artikelnummer: Cay39597-1
4'-methyl-alpha-Pyrrolidinohexanophenone (hydrochloride) (exempt preparation) (Cay-39597) is an analytical reference material categorized as a cathinone. 4'-methyl-alpha-Pyrrolidinohexanophenone has been detected in products sold as liquid aroma. 4'-methyl-alpha-Pyrrolidinohexanophenone is regulated as a Schedule I...
Schlagworte: | 4'-methyl PHP, 4'-methyl-alpha-PHP, MPHP, PV4, 1-(4-methylphenyl)-2-(1-pyrrolidinyl)-1-hexanone, monohydrochloride |
Anwendung: | Analytical reference material, cathinone |
CAS | 1391052-36-0 |
MW: | 295.9 D |
332,00 €
Artikelnummer: Cay16217-100
Guanethidine is an antihypertensive compound that competes with norepinephrine for transport into presynaptic terminals of adrenergic neurons by the norepinephrine transporter. Once guanethidine has entered the nerve, it becomes concentrated in synaptic vesicles, depleting endogenous norepinephrine, and thus,...
Schlagworte: | N-[2-(hexahydro-1(2H)-azocinyl)ethyl]-guanidine, monosulfate |
Anwendung: | Antihypertensive compound |
CAS | 645-43-2 |
MW: | 296.4 D |
ab 77,00 €
Artikelnummer: Cay15921-1
Trimipramine is a tricyclic antidepressant. It selectively binds the serotonin (5-HT) transporter (SERT) over the norepinephrine transporter (NET) and dopamine transporter (DAT, Kds = 149, 2,450, and 3,780 nM, respectively) and acts as a histamine H1 receptor antagonist (Ki = 0.02 µM) that is selective for histamine...
Schlagworte: | 10,11-dihydro-N,N,beta-trimethyl-5H-dibenz[b,f]azepine-5-propanamine, (2Z)-2-butenedioate |
Anwendung: | Noradrenalin transporter inhibitor, Serotonin transporter inhibitor |
CAS | 521-78-8 |
MW: | 410.5 D |
ab 46,00 €
Artikelnummer: LKT-D8145.100
Duloxetine is a serotonin/norepinephrine reuptake inhibitor (SNRI). It is used as an antidepressant and anxiolytic.
Schlagworte: | LY-248686 hydrochloride, Cymbalta, Ariclaim, (+)-(S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine... |
CAS | 136434-34-9 |
MW: | 333.88 D |
ab 121,00 €
Artikelnummer: ARG11072.100
Protein function: Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals. [The UniProt Consortium]
Schlagworte: | Anti-NET, Anti-Slc6a2, Anti-Norepinephrine transporter, Anti-Solute carrier family 6 member 2, Anti-Sodium-dependent... |
Anwendung: | WB |
Wirt: | Mouse |
Spezies-Reaktivität: | mouse, rat |
882,00 €