Zu "K04977" wurden 22 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
-15 %
Rabattaktion
Anti-TRPM2
Artikelnummer: A300-414A
Protein function: Isoform 1: Nonselective, voltage-independent cation channel that mediates Na(+) and Ca(2+) influx, leading to increased cytoplasmic Ca(2+) levels (PubMed:11960981, PubMed:12594222, PubMed:11385575, PubMed:11509734, PubMed:11804595, PubMed:15561722, PubMed:16601673, PubMed:19171771, PubMed:20660597,...
| Schlagworte: | Anti-TrpC7, Anti-TRPM2, Anti-LTrpC2, Anti-LTrpC-2, Anti-Transient receptor potential channel 7, Anti-Transient receptor... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
164,00 €
ab 139,40 €
Tat-M2NX (trifluoroacetate salt)
Artikelnummer: Cay37447-1
Tat-M2NX is a peptide antagonist of transient receptor potential melastatin 2 (TRPM2). It inhibits hydrogen peroxide-induced calcium influx in HEK293 cells expressing human TRPM2 when used at concentrations ranging from 25 to 100 µM. In vivo, Tat-M2NX (20 mg/kg) reduces brain infarct volume in male, but not female,...
| Anwendung: | Peptide TRPM2 antagonist |
| MW: | 4354.2 D |
ab 90,00 €
N-(p-amylcinnamoyl) Anthranilic Acid
Artikelnummer: Cay14531-25
N-(p-amylcinnamoyl) Anthranilic acid (ACA) is a channel blocker that acts on several transient receptor potential (TRP) channels, including TRPM2, TRPM8, and TRPC6 (IC50 = 1.7, 3.8, and 2.3 µM, respectively). It is a weak inhibitor of TRPV1. ACA is also an inhibitor of phospholipase A2, blocking the release of...
| Schlagworte: | ACA, 2-[[1-oxo-3-(4-pentylphenyl)-2-propen-1-yl]amino]-benzoic acid |
| Anwendung: | TRP channel blocker |
| CAS | 110683-10-8 |
| MW: | 337.4 D |
ab 84,00 €
Cyclic ADP-Ribose (ammonium salt)
Artikelnummer: Cay21417-1
Cyclic ADP-ribose (cADP-ribose) is an endogenous metabolite of NAD+ that mobilizes the release of stored Ca2+ in the endoplasmic reticulum via ryanodine receptors in various cell types.{12737, 11940, 20368, 34320, 34319} This second messenger is generated via the cADP-ribose synthases CD38 and CD157.{20368, 34319,...
| Schlagworte: | cADPR, cADP-Ribose, 1-beta-D-ribofuranosyl-adenosine 5'-(trihydrogen diphosphate), intramol. P',5''-ester, diammonium salt |
| Anwendung: | Endogenous NAD+ metabolite, second messenger |
| MW: | 575.4 D |
ab 272,00 €
Anti-TRPM2
Artikelnummer: E-AB-61822.120
The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript...
| Schlagworte: | Anti-TrpC7, Anti-TRPM2, Anti-LTrpC2, Anti-LTrpC-2, Anti-Transient receptor potential channel 7, Anti-Transient receptor... |
| Anwendung: | IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 198,00 €
Anti-TRPM2
Artikelnummer: ARG40778.50
Protein function: Isoform 1: Nonselective, voltage-independent cation channel that mediates Na(+) and Ca(2+) influx, leading to increased cytoplasmic Ca(2+) levels (PubMed:11960981, PubMed:12594222, PubMed:11385575, PubMed:11509734, PubMed:11804595, PubMed:15561722, PubMed:16601673, PubMed:19171771, PubMed:20660597,...
| Schlagworte: | Anti-TrpC7, Anti-TRPM2, Anti-LTrpC2, Anti-LTrpC-2, Anti-Transient receptor potential channel 7, Anti-Transient receptor... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
520,00 €
Anti-TRPM2
Artikelnummer: ARG40825.100
Protein function: Isoform 1: Nonselective, voltage-independent cation channel that mediates Na(+) and Ca(2+) influx, leading to increased cytoplasmic Ca(2+) levels (PubMed:11960981, PubMed:12594222, PubMed:11385575, PubMed:11509734, PubMed:11804595, PubMed:15561722, PubMed:16601673, PubMed:19171771, PubMed:20660597,...
| Schlagworte: | Anti-TrpC7, Anti-TRPM2, Anti-LTrpC2, Anti-LTrpC-2, Anti-Transient receptor potential channel 7, Anti-Transient receptor... |
| Anwendung: | ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
624,00 €
Anti-TRPM2
Artikelnummer: ATA-HPA030976.100
Protein function: [Isoform 1]: Nonselective, voltage-independent cation channel that mediates Na(+) and Ca(2+) influx, leading to increased cytoplasmic Ca(2+) levels (PubMed:11960981, PubMed:12594222, PubMed:11385575, PubMed:11509734, PubMed:11804595, PubMed:15561722, PubMed:16601673, PubMed:19171771,...
| Schlagworte: | Anti-TrpC7, Anti-TRPM2, Anti-LTrpC2, Anti-LTrpC-2, Anti-Transient receptor potential channel 7, Anti-Transient receptor... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 300,00 €
Anti-TRPM2
Artikelnummer: ATA-HPA035260.100
Protein function: [Isoform 1]: Nonselective, voltage-independent cation channel that mediates Na(+) and Ca(2+) influx, leading to increased cytoplasmic Ca(2+) levels (PubMed:11960981, PubMed:12594222, PubMed:11385575, PubMed:11509734, PubMed:11804595, PubMed:15561722, PubMed:16601673, PubMed:19171771,...
| Schlagworte: | Anti-TrpC7, Anti-TRPM2, Anti-LTrpC2, Anti-LTrpC-2, Anti-Transient receptor potential channel 7, Anti-Transient receptor... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 300,00 €
Anti-TRPM2 / EREG1
Artikelnummer: NSJ-RQ6967
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Transient receptor potential cation channel subfamily M member 2 (TRPM2), also known as Estrogen-responsive element-associated gene 1 (EREG1), is a protein that in humans is encoded by the TRPM2 gene. Using a cosmid/BAC contig, this gene is mapped to chromosome...
| Schlagworte: | Anti-TrpC7, Anti-TRPM2, Anti-LTrpC2, Anti-LTrpC-2, Anti-Transient receptor potential channel 7, Anti-Transient receptor... |
| Anwendung: | WB, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
2'-Deoxyadenosine-5'-O-diphosphoribose (sodium salt)
Artikelnummer: Cay38356-500
2'-Deoxyadenosine-5'-O-diphosphoribose is a transient receptor potential melastatin 2 (TRPM2) agonist. It increases calcium-induced currents in an inside-out patch clamp assay using HEK293 cells expressing human TRPM2 when used at a concentration of 30 µM. 2'-Deoxyadenosine-5'-O-diphosphoribose has been found in...
| Schlagworte: | 2'-deoxy ADPR, 2'-deoxy-adenosine 5'-(trihydrogen diphosphate), P'->5-ester with D-ribose, disodium salt |
| Anwendung: | TRPM2 agonist |
| MW: | 587.3 D |
582,00 €
2'-deoxy NAD+ (sodium salt)
Artikelnummer: Cay38386-600
2'-deoxy NAD+ is a transient receptor potential melastatin 2 (TRPM2) agonist. It increases calcium-induced currents in an inside-out patch clamp assay using HEK293 cells expressing human TRPM2 when used at a concentration of 30 µM. 2'-deoxy NAD+ has been found in Jurkat T cells. It also is a substrate of...
| Schlagworte: | 2'-deoxy-Nicotinamide adenine dinucleotide, 2'-deoxy-adenosine 5'-(trihydrogen diphosphate), P'->5'-ester with... |
| Anwendung: | TRPM2 agonist |
| CAS | 1514900-83-4 |
| MW: | 669.4 D |
505,00 €