Zu "K04973" wurden 46 Artikel gefunden!
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GSK1016790A
Artikelnummer: TGM-T6848-1mg
Description: GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelial cells. Target: TRP/TRPV Channel, Calcium Channel. Smiles: CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N1CCN(CC1)C(=O)[C@H](CO)NS(=O)(=O)c1ccc(Cl)cc1Cl....
| Schlagworte: | GSK101 |
| Anwendung: | TRPV4 agonist |
| CAS | 942206-85-1 |
| MW: | 655.61 D |
ab 31,00 €
4alpha-PDD
Artikelnummer: TGM-T26386-1mg
Description: 4alpha-PDD activates transient receptor potential vanilloid 4 (TRPV4) channels and is inactive for signaling through PKC. Target: Others. Smiles: O(C(CCCCCCCCC)=O)[C@@]12[C@@](C1(C)C)([C@]3([C@](O)([C@H](C)[C@H]2OC(CCCCCCCCC)=O)[C@]4([C@@](O)(CC(CO)=C3)C(=O)C(C)=C4)[H])[H])[H]. References: Chen CK, Hsu...
| Schlagworte: | 4alpha-Phorbol 12,13-didecanoate |
| Anwendung: | Phorbol ester negative control, TRPV4 agonist |
| CAS | 27536-56-7 |
| MW: | 672.93 D |
ab 248,00 €
RN-9893 (hydrochloride)
Artikelnummer: TGM-T37321-1mg
Description: RN-9893 is an antagonist of transient receptor potential vanilloid 4 (TRPV4, IC50s = 0.42 and 0.66 µM, respectively, for the human and rat receptors).1 It is selective for TRPV4 over TRPV1, TRPV3, and TRPM8 (IC50s = 10, >30, and 30 µM, respectively). RN-9893 reduces rat TRPV4 activity induced by...
| Anwendung: | TRPV4 antagonist |
| CAS | 2109450-40-8 |
| MW: | 536.95 D |
84,00 €
HC-067047
Artikelnummer: TGM-T4680-100mg
Description: HC-067047 is a potent and selective TRPV4 antagonist that also inhibits the endogenous TRPV4-mediated response to 4alpha-PDH. Target: TRP/TRPV Channel. Smiles: Cc1c(cc(-c2ccccc2)n1CCCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F. References: Everaerts W et al. Inhibition of the cation channel TRPV4 improves bladder...
| Schlagworte: | HC067047 |
| Anwendung: | TRPV4 antagonist |
| CAS | 883031-03-6 |
| MW: | 471.51 D |
ab 31,00 €
GSK2193874
Artikelnummer: TGM-T5640-100mg
Description: GSK2193874 was identified as a selective, orally active TRPV4 blocker. Target: TRP/TRPV Channel. Smiles: FC(F)(F)c1cccc(c1)-c1nc2cc(Br)ccc2c(C(=O)NC2(CC2)c2ccccc2)c1CN1CCC(CC1)N1CCCCC1. References: Cheung M , Bao W , Behm D J , et al. Discovery of GSK2193874: An Orally Active, Potent, and Selective...
| Anwendung: | TRPV4 antagonist |
| CAS | 1336960-13-4 |
| MW: | 691.62 D |
ab 37,00 €
Transient receptor potential cation channel subfamily V...
Artikelnummer: CSB-EP875332MO1.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-469aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MADPGDGPRA APGEVAEPPG DESGTSGGEA FPLSSLANLF EGEEGSSSLS PVDASRPAGP GDGRPNLRMK FQGAFRKGVP NPIDLLESTL YESSVVPGPK KAPMDSLFDY GTYRHHPSDN KRWRRKVVEK QPQSPKAPAP...
| Schlagworte: | TrpV4, Trpv4, Trp12, TRP12, VR-OAC, OTRPC4, Osm-9-like TRP channel 4, Vanilloid receptor-like channel 2, Vanilloid... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 59.9 kD |
ab 364,00 €
Transient receptor potential cation channel subfamily V...
Artikelnummer: CSB-EP875332MO4.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 723-871aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: GQVSKESKHI WKLQWATTIL DIERSFPVFL RKAFRSGEMV TVGKSSDGTP DRRWCFRVDE VNWSHWNQNL GIINEDPGKS EIYQYYGFSH TVGRLRRDRW SSVVPRVVEL NKNSSADEVV VPLDNLGNPN CDGHQQGYAP...
| Schlagworte: | TrpV4, Trpv4, Trp12, TRP12, VR-OAC, OTRPC4, Osm-9-like TRP channel 4, Vanilloid receptor-like channel 2, Vanilloid... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 21.2 kD |
ab 364,00 €
Transient receptor potential cation channel subfamily V...
Artikelnummer: CSB-EP875332MO4e1.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 723-871aa. Protein Length: Partial. Tag Info: Tag-Free. Target Protein Sequence: GQVSKESKHI WKLQWATTIL DIERSFPVFL RKAFRSGEMV TVGKSSDGTP DRRWCFRVDE VNWSHWNQNL GIINEDPGKS EIYQYYGFSH TVGRLRRDRW SSVVPRVVEL NKNSSADEVV VPLDNLGNPN CDGHQQGYAP KWRTDDAPL....
| Schlagworte: | TrpV4, Trpv4, Trp12, TRP12, VR-OAC, OTRPC4, Osm-9-like TRP channel 4, Vanilloid receptor-like channel 2, Vanilloid... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 17.3 kD |
ab 512,00 €
Anti-TRPV4
Artikelnummer: CSB-PA004651.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-VRL2, Anti-VRL-2, Anti-TRPV4, Anti-TrpV4, Anti-TRP12, Anti-VR-OAC, Anti-OTRPC4, Anti-Osm-9-like TRP channel 4,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-TRPV4
Artikelnummer: CSB-PA024643.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: TRPV4. Antigen Species: Human
| Schlagworte: | Anti-VRL2, Anti-VRL-2, Anti-TRPV4, Anti-TrpV4, Anti-TRP12, Anti-VR-OAC, Anti-OTRPC4, Anti-Osm-9-like TRP channel 4,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-TRPV4
Artikelnummer: CSB-PA160091.100
Host Species: Rabbit. Isotype: IgG. Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific...
| Schlagworte: | Anti-VRL2, Anti-VRL-2, Anti-TRPV4, Anti-TrpV4, Anti-TRP12, Anti-VR-OAC, Anti-OTRPC4, Anti-Osm-9-like TRP channel 4,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-TRPV4
Artikelnummer: CSB-PA558953.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: TRPV4. Antigen Species: Human
| Schlagworte: | Anti-VRL2, Anti-VRL-2, Anti-TRPV4, Anti-TrpV4, Anti-TRP12, Anti-VR-OAC, Anti-OTRPC4, Anti-Osm-9-like TRP channel 4,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €