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SAR7334 hydrochloride
SAR7334 hydrochloride

Artikelnummer: TGM-T12849L-100mg

Description: SAR7334 hydrochloride, a potent and specific inhibitor of TRPC6 (IC50 of 7.9 nM), effectively targets and inhibits the TRPC6 channel. Target: Others. Smiles: Cl.Cl.N[C@@H]1CCCN(C1)[C@@H]1Cc2ccccc2[C@H]1Oc1ccc(cc1Cl)C#N. References: Ilatovskaya DV, et al. The Role of Angiotensin II in Glomerular Volume...
Anwendung: TRPC6 blocker
CAS 1333207-63-8
MW: 440.79 D
ab 78,00 €
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TRPC3/6-IN-1
TRPC3/6-IN-1

Artikelnummer: TGM-T61407-10mg

Description: TRPC3/6-IN-1 is a highly potent and selective inhibitor that blocks the activity of canonical transient receptor channels TRPC3 and TRPC6, showing significant potency against human isoforms hTRPC3 and hTRPC6 with IC50 values of 1260 nM and 500 nM, respectively. This compound is valuable for research on...
Anwendung: TRPC3 / TRPC6 inhibitor
CAS 736945-96-3
MW: 365.45 D
ab 83,00 €
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Short transient receptor potential channel 6 (TRPC6), partial, human, recombinant
Short transient receptor potential channel 6 (TRPC6),...

Artikelnummer: CSB-MP1339HU.1

Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 543-592aa. Protein Length: Partial. Tag Info: C-terminal hFc-tagged. Target Protein Sequence: ARFMAFWHAS KAQSIIDAND TLKDLTKVTL GDNVKYYNLA RIKWDPSDPQ. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological...
Schlagworte: TrpC6, TRP-6, Transient receptor protein 6, Short transient receptor potential channel 6, Recombinant Human Short...
Anwendung: Activity not tested
Exprimiert in: Mammalian cells
Ursprungsart: human
MW: 34.7 kD
ab 598,00 €
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BI-749327
BI-749327

Artikelnummer: Cay39672-1

BI-749327 is an inhibitor of transient receptor potential canonical 6 (TRPC6, IC50 = 13 nM for the mouse channel). It is selective for TRPC6 over TRPC3 and TRPC7 (IC50s = 1,100 and 550 nM, respectively, for the mouse channels). BI-749327 (100, 250, and 500 nM) inhibits TRPC6-mediated reporter gene expression in...
Schlagworte: [4-(6-amino-3-pyridazinyl)-1-piperidinyl][4-[4-(trifluoromethyl)phenoxy]phenyl]-methanone
Anwendung: TRPC6 inhibitor
CAS 2361241-23-6
MW: 442.4 D
ab 103,00 €
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Anti-TRPC6
Anti-TRPC6

Artikelnummer: CSB-PA215862.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: TRPC6. Antigen Species: Human
Schlagworte: Anti-TrpC6, Anti-TRP-6, Anti-Transient receptor protein 6, Anti-Short transient receptor potential channel 6, bZ1P14.9...
Anwendung: ELISA, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 165,00 €
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Anti-TRPC6
Anti-TRPC6

Artikelnummer: CSB-PA281056.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: TRPC6. Antigen Species: Human
Schlagworte: Anti-TrpC6, Anti-TRP-6, Anti-Transient receptor protein 6, Anti-Short transient receptor potential channel 6, bZ1P14.9...
Anwendung: ELISA, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 165,00 €
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Anti-TRPC6, clone TRPC6/7671
Anti-TRPC6, clone TRPC6/7671

Artikelnummer: NSJ-V4149-100UG

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Phenylalanine hydroxylase (PAH), tyrosine hydroxylase (TH) and tryptophan hydroxylase (TPH) comprise a small family of monooxygenases that use tetrahydropterine as a cofactor during the catabolism of aromatic L-amino acids. PAH, TH and TPH all...
Schlagworte: Anti-TRP-6, Anti-TrpC6, Anti-Transient receptor protein 6, Anti-Short transient receptor potential channel 6, TRPC6 Antibody
Anwendung: IHC (paraffin)
Wirt: Mouse
Spezies-Reaktivität: human
ab 361,00 €
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Anti-TRPC6, clone TRPC6/7671
Anti-TRPC6, clone TRPC6/7671

Artikelnummer: NSJ-V4149SAF-100UG

1 mg/ml in 1X PBS, BSA free, sodium azide free. Phenylalanine hydroxylase (PAH), tyrosine hydroxylase (TH) and tryptophan hydroxylase (TPH) comprise a small family of monooxygenases that use tetrahydropterine as a cofactor during the catabolism of aromatic L-amino acids. PAH, TH and TPH all contain catalytic domains...
Schlagworte: Anti-TRP-6, Anti-TrpC6, Anti-Transient receptor protein 6, Anti-Short transient receptor potential channel 6, TRPC6 Antibody
Anwendung: IHC (paraffin)
Wirt: Mouse
Spezies-Reaktivität: human
781,00 €
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Anti-TRPC6, clone TRPC6/7672
Anti-TRPC6, clone TRPC6/7672

Artikelnummer: NSJ-V4150-100UG

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Phenylalanine hydroxylase (PAH), tyrosine hydroxylase (TH) and tryptophan hydroxylase (TPH) comprise a small family of monooxygenases that use tetrahydropterine as a cofactor during the catabolism of aromatic L-amino acids. PAH, TH and TPH all...
Schlagworte: Anti-TRP-6, Anti-TrpC6, Anti-Transient receptor protein 6, Anti-Short transient receptor potential channel 6, TRPC6 Antibody
Anwendung: IHC (paraffin)
Wirt: Mouse
Spezies-Reaktivität: human
ab 361,00 €
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Anti-TRPC6, clone TRPC6/7672
Anti-TRPC6, clone TRPC6/7672

Artikelnummer: NSJ-V4150SAF-100UG

1 mg/ml in 1X PBS, BSA free, sodium azide free. Phenylalanine hydroxylase (PAH), tyrosine hydroxylase (TH) and tryptophan hydroxylase (TPH) comprise a small family of monooxygenases that use tetrahydropterine as a cofactor during the catabolism of aromatic L-amino acids. PAH, TH and TPH all contain catalytic domains...
Schlagworte: Anti-TRP-6, Anti-TrpC6, Anti-Transient receptor protein 6, Anti-Short transient receptor potential channel 6, TRPC6 Antibody
Anwendung: IHC (paraffin)
Wirt: Mouse
Spezies-Reaktivität: human
781,00 €
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SAR7334 (hydrochloride)
SAR7334 (hydrochloride)

Artikelnummer: Cay28292-1

SAR7334 is a transient receptor potential canonical 6 (TRPC6) channel blocker (IC50 = 7.9 nM). It is selective for TRPC6 over TRPC4 and TRPC5 (IC50s = 282 and 226 nM, respectively). SAR7334 (0.2-1 µM) blocks TRPC6-dependent hypoxia-induced vasoconstriction in isolated perfused and ventilated mouse lung. It also...
Schlagworte: 4-[[(1R,2R)-2-[(3R)-3-amino-1-piperidinyl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chloro-benzonitrile, dihydrochloride
Anwendung: TRPC6 blocker
CAS 1333207-63-8
MW: 440.8 D
ab 52,00 €
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GSK1702934A
GSK1702934A

Artikelnummer: Cay34576-1

GSK1702934A is an activator of transient receptor potential canonical 3 (TRPC3) and TRPC6. It induces TRPC3- and TRPC6-dependent currents in whole-cell patch-clamp assays using HEK293 cells expressing the human channels (EC50s = 0.08 and 0.44 µM, respectively). GSK1702934A enhances contractility and induces...
Schlagworte: 1,3-dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one
Anwendung: TRPC3 / TRPC6 activator
CAS 924377-85-5
MW: 395.5 D
ab 44,00 €
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