Zu "K04961" wurden 20 Artikel gefunden!
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S107
Artikelnummer: TGM-T3438-100mg
Description: S107 is a RyR-selective 1, 4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels. Target: Others. Smiles: COc1ccc2SCCN(C)Cc2c1. References: Lehnart SE, et al. Leaky Ca
| Anwendung: | RyR1-FKBP12 protein-protein interaction stabilizer |
| CAS | 927871-76-9 |
| MW: | 209.31 D |
ab 39,00 €
Ryanodine receptor 1 (RYR1), partial, human, recombinant
Artikelnummer: CSB-EP020619HUb0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-534. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MGDAEGEDEV QFLRTDDEVV LQCSATVLKE QLKLCLAAEG FGNRLCFLEP TSNAQNVPPD LAICCFVLEQ SLSVRALQEM LANTVEAGVE SSQGGGHRTL LYGHAILLRH AHSRMYLSCL TTSRSMTDKL AFDVGLQEDA...
| Schlagworte: | RYR1, RyR1, RYDR, RYR-1, Ryanodine receptor 1, Type 1 ryanodine receptor, Skeletal muscle ryanodine receptor, Skeletal... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 65.4 kD |
ab 354,00 €
Anti-RYR1
Artikelnummer: CSB-PA050519.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: RYR1. Antigen Species: Human
| Schlagworte: | Anti-RYDR, Anti-RYR1, Anti-RyR1, Anti-RYR-1, Anti-Ryanodine receptor 1, Anti-Type 1 ryanodine receptor, Anti-Skeletal... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Anti-RYR1
Artikelnummer: CSB-PA243333.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: RYR1. Antigen Species: Human
| Schlagworte: | Anti-RYDR, Anti-RYR1, Anti-RyR1, Anti-RYR-1, Anti-Ryanodine receptor 1, Anti-Type 1 ryanodine receptor, Anti-Skeletal... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Suramin (sodium salt)
Artikelnummer: Cay11126-100
Suramin is a polysulfonated naphthylurea with antiviral, antiparasitic, and anticancer activities. It is negatively charged at physiological pH and therefore binds to various intracellular targets including, but not limited to, ryanodine receptor 1 (IC50 = 4.9 µM), G protein-coupled receptors, P2 purinergic...
| Schlagworte: | BAY 205, Germanin, NF 060,... |
| Anwendung: | Ryanodine receptor agonist |
| CAS | 129-46-4 |
| MW: | 1429.1 D |
ab 150,00 €
Dantrolene (sodium salt)
Artikelnummer: Cay14326-100
Dantrolene is an inhibitor of calcium release from the sarcoplasmic reticulum (IC50 = 0.3 µM). It binds to sarcoplasmic reticulum vesicles isolated from normal and malignant hyperthermia-susceptible (MHS) pigs with Kd values of 0.3 and 0.09 µM, respectively. Dantrolene reduces spontaneous calcium wave frequency and...
| Schlagworte: | 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-2,4-imidazolidinedione, monosodium salt |
| Anwendung: | Ca release inhibitor |
| CAS | 14663-23-1 |
| MW: | 336.2 D |
ab 85,00 €
Mouse RYR1 (Ryanodine Receptor 1, Skeletal) ELISA Kit
Artikelnummer: ELK-ELK6157.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse RYR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse RYR1. Next,...
| Schlagworte: | RyR1, RYR-1, Ryanodine receptor 1, Type 1 ryanodine receptor, Skeletal muscle ryanodine receptor, Skeletal muscle-type... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Human RYR1 (Ryanodine Receptor 1, Skeletal) ELISA Kit
Artikelnummer: ELK-ELK4430.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human RYR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human RYR1. Next,...
| Schlagworte: | RYDR, RyR1, RYR-1, Ryanodine receptor 1, Type 1 ryanodine receptor, Skeletal muscle ryanodine receptor, Skeletal... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
S107
Artikelnummer: Cay13253-5
S107 is a stabilizer of the protein-protein interaction between ryanodine receptor 1 (RyR1) and FK-506 binding protein 1A (FKBP12). It stabilizes sarcoplasmic reticulum RyR1 channels by decreasing the dissociation of FKBP12 in isolated mouse muscle fibers. S107 (50 and 100 µM) also reduces neurite growth and length...
| Schlagworte: | 2,3,4,5-tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine |
| Anwendung: | RyR1-FKBP12 protein-protein interaction stabilizer |
| CAS | 927871-76-9 |
| MW: | 209.3 D |
ab 109,00 €
Human Ryanodine receptor 1 / RYR1 ELISA Kit
Artikelnummer: G-HUFI01314.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Dantrolene-d4
Artikelnummer: Cay29451-1
Dantrolene-d4 is intended for use as an internal standard for the quantification of dantrolene (Cay-14326) by GC- or LC-MS. Dantrolene is an inhibitor of calcium release from the sarcoplasmic reticulum (IC50 = 0.3 µM). It binds to sarcoplasmic reticulum vesicles isolated from normal and malignant...
| Schlagworte: | 1-[[[5-(4-nitrophenyl)-furanyl]methylene]amino]-2,4-imidazolidinedione |
| Anwendung: | GC-MS, LC-MS, internal standard, Ca2+ release inhibitor |
| CAS | 2749234-17-9 |
| MW: | 318.3 D |
286,00 €
Anti-RYR1
Artikelnummer: ATA-HPA056416.100
Protein function: Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules (PubMed:11741831, PubMed:16163667). Repeated very high-level exercise increases the open...
| Schlagworte: | Anti-RyR1, Anti-RYDR, Anti-RYR1, Anti-RYR-1, Anti-Ryanodine receptor 1, Anti-Type 1 ryanodine receptor, Anti-Skeletal... |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 300,00 €