Zu "K04957" wurden 20 Artikel gefunden!
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ZD7288
Artikelnummer: TGM-T7516-100mg
Description: ZD7288 (ICI D7288), a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity. Target: HCN Channel. Smiles: Cl.CCN(c1ccccc1)c1cc(=NC)n(C)c(C)n1. References: Zhang X X , Min X C , Xu X L , et al. ZD7288, a selective...
| Schlagworte: | ICI D7288 |
| Anwendung: | HCN channel blocker |
| CAS | 133059-99-1 |
| MW: | 292.81 D |
ab 31,00 €
Anti-HCN4
Artikelnummer: CSB-PA209337.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: HCN4. Antigen Species: Human
| Schlagworte: | Anti-HCN4, Anti-Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, HCN4Potassium/sodium... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-HCN4
Artikelnummer: CSB-PA231041.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: HCN4. Antigen Species: Human
| Schlagworte: | Anti-HCN4, Anti-Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, HCN4Potassium/sodium... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
ZD 7288
Artikelnummer: Cay15228-50
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated (HCN) channels contribute to native pacemaker currents in heart and neurons and modulate cardiac and neuronal excitability. Certain HCN channels also accentuate neuropathic pain. ZD 7288 is a potent blocker of HCN channels that inhibits HCN4 more...
| Schlagworte: | ICI-D 7288, N-ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-4-pyrimidinamine, monohydrochloride |
| Anwendung: | HCN channel blocker |
| CAS | 133059-99-1 |
| MW: | 292.8 D |
ab 94,00 €
Human HCN4 ELISA Kit
Artikelnummer: G-HUFI01251.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-HCN4, clone S114-10
Artikelnummer: 200-301-F43
Anti-HCN4 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with HCN4 from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. No cross-reactivity against other HCNs. Cross-reactivity with HCN4 from other sources has not been determined....
| Schlagworte: | Anti-Hcn4, Anti-Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 |
| Anwendung: | IHC, IFM, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
737,00 €
Ivabradine (hydrochloride)
Artikelnummer: Cay15868-50
Ivabradine is a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker that blocks the mixed sodium/potassium inward funny current (If) in HEK293 cells expressing mouse HCN1, human HCN2, and human HCN4 (EC50s = 4.5, 4.52, and 4.28 µM, respectively). In vivo, ivabradine (10 mg/kg per day) reduces...
| Schlagworte: | S 16257,... |
| Anwendung: | If (HCN1 / HCN2 / HCN4) channel blocker |
| CAS | 148849-67-6 |
| MW: | 505.1 D |
ab 100,00 €
DK-AH 269
Artikelnummer: Cay21425-5
DK-AH 269 blocks hyperpolarization-activated cyclic nucleotide-gated (HCN) channels (IC50 = 0.62 µM in mouse sinoatrial node cells). DK-AH 269 slows heart rate by decreasing the spontaneous firing rate of the sinoatrial node in the heart. Using telemetric ECG recordings in mice, it reduced heart rate in a...
| Schlagworte: | Cilobradine,... |
| Anwendung: | HCN channel blocker |
| CAS | 186097-54-1 |
| MW: | 519.1 D |
ab 55,00 €
Ivabradine-d3 (hydrochloride)
Artikelnummer: Cay25711-500
Ivabradine-d3 is intended for use as an internal standard for the quantification of ivabradine (Cay-15868) by GC- or LC-MS. Ivabradine is a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker that blocks the mixed sodium/potassium inward funny current (If) in HEK293 cells expressing mouse HCN1,...
| Schlagworte: | (S)-3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl-d3)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetr... |
| Anwendung: | If (HCN1 / HCN2 / HCN4) channel blocker, GC-MS, LC-MS, internal standard |
| CAS | 1217809-61-4 |
| MW: | 508.1 D |
ab 293,00 €
Anti-HCN4
Artikelnummer: NSJ-RQ6995
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 is a protein that in humans is encoded by the HCN4 gene. This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein...
| Schlagworte: | Anti-HCN4, Anti-Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, HCN4 Antibody |
| Anwendung: | WB, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
772,00 €
Human HCN4 (Hyperpolarization Activated Cyclic Nucleotide...
Artikelnummer: ELK-ELK5355.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HCN4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HCN4. Next,...
| Schlagworte: | HCN4, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Nanodisc Human HCN4 Protein
Artikelnummer: G-HDFP662.96
Protein function: Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat. May contribute to the native pacemaker currents in...
| Schlagworte: | HCN4, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
748,00 €