Zu "K04944" wurden 20 Artikel gefunden!
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RA-2
Artikelnummer: TGM-T24701-10mg
Description: RA-2 is a pan-negative-gating modulator of KCa2/3 channels that acts by inhibiting EDH-type relaxation in coronary arteries. Target: Others. Smiles: C(OCC1=CC(COC(=O)C2=CC(F)=C(O)C=C2)=CC=C1)(=O)C3=CC(F)=C(O)C=C3. References: Uttley L, Bermejo I, Ren S, Martyn-St James M, Wong R, Scott DL, Young A,...
| Schlagworte: | RA2 |
| Anwendung: | KCa2.3 / KCa3.1 inhibitor |
| CAS | 1867107-62-7 |
| MW: | 414.36 D |
ab 142,00 €
NS13001
Artikelnummer: TGM-T16345-100mg
Description: NS13001 (N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine) is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels). The EC50s are 1.8 and 0.14 µM for SK2 and SK3, respectively. NS13001 holds...
| Schlagworte: | N-(4-chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-9-methylpurin-6-amine,... |
| Anwendung: | KCa2.2/SK2 / KCa2.3/SK3 positive allosteric modulator |
| CAS | 1063331-94-1 |
| MW: | 353.81 D |
ab 45,00 €
Anti-KCNN3
Artikelnummer: CSB-PA838540.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen....
| Schlagworte: | Anti-K3, Anti-SK3, Anti-SKCa3, Anti-KCNN3, Anti-SKCa 3, Anti-KCa2.3, Anti-Small conductance calcium-activated potassium... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
126,00 €
CyPPA
Artikelnummer: Cay15614-50
CyPPA is a positive modulator of the small-conductance calcium-activated potassium channels KCa2.2/SK2 and KCa2.3/SK3 (EC50s = 14 and 5.6 µM, respectively). It is inactive on both KCa2.1/SK1 and the intermediate conductance calcium-activated potassium channel, KCa3.1/SK4. At KCa2.3/SK3, CyPPA increases the apparent...
| Schlagworte: | N-cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methyl-4-pyrimidinamine |
| Anwendung: | Small conductance calcium-activated channel SK2/SK3 modulator |
| CAS | 73029-73-9 |
| MW: | 285.4 D |
ab 174,00 €
Anti-KCNN3
Artikelnummer: E-AB-18172.120
KCNN3 (Potassium Calcium-Activated Channel Subfamily N Member 3) is a Protein Coding gene. Diseases associated with KCNN3 include Spinocerebellar Ataxia 2 and Bipolar Disorder. Among its related pathways are Insulin secretion and Transmission across Chemical Synapses. GO annotations related to this gene include...
| Schlagworte: | Anti-K3, Anti-SK3, Anti-SKCa3, Anti-KCNN3, Anti-KCa2.3, Anti-SKCa 3, Anti-Small conductance calcium-activated potassium... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-KCNN3
Artikelnummer: E-AB-52084.120
KCNN3 (Potassium Calcium-Activated Channel Subfamily N Member 3) is a Protein Coding gene. Diseases associated with KCNN3 include Spinocerebellar Ataxia 2 and Bipolar Disorder. Among its related pathways are Insulin secretion and Transmission across Chemical Synapses. GO annotations related to this gene include...
| Schlagworte: | Anti-K3, Anti-SK3, Anti-SKCa3, Anti-KCNN3, Anti-KCa2.3, Anti-SKCa 3, Anti-Small conductance calcium-activated potassium... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
SKA-31
Artikelnummer: Cay29690-5
SKA-31 is an activator of the small- and intermediate conductance calcium-activated potassium channels KCa2.1, KCa2.2, KCa2.3, and KCa3.1 (EC50s = 2.9, 1.9, 2.9, and 0.26 µM, respectively, in a patch-clamp assay). It also blocks the voltage-gated potassium (Kv) channels Kv1.3, Kv1.5, Kv3.1, and Kv3.2 by 10 to 30%...
| Schlagworte: | 2-Aminonaphthiazole, naphtho[1,2-d]thiazol-2-amine |
| Anwendung: | KCa2/3 channel activator |
| CAS | 40172-65-4 |
| MW: | 200.3 D |
ab 73,00 €
NS 13001
Artikelnummer: Cay37317-1
NS 13001 is a positive allosteric modulator for small-conductance calcium-activated potassium channel 2 (KCa2.2/SK2) and KCa2.3/SK3. It increases calcium-induced currents in an inside-out patch clamp assay using HEK293 cells expressing human KCa2.2/SK2 or KCa2.3/SK3 (EC50s = 1.8 and 0.14 µM, respectively). Oral...
| Schlagworte: | N-(4-chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine |
| Anwendung: | KCa2.2/SK2 / KCa2.3/SK3 positive allosteric modulator |
| CAS | 1063331-94-1 |
| MW: | 353.8 D |
ab 48,00 €
RA-2
Artikelnummer: Cay39567-10
RA-2 is an inhibitor of small-conductance calcium-activated potassium channel 2.3 (KCa2.3/SK3) and intermediate-conductance calcium-activated potassium channel 3.1 (KCa3.1/IK1) (IC50s = 2 and 17 nM, respectively). It is selective for these channels over KCa1.1/BK1, voltage-gated potassium channel 1.2 (Kv1.2), Kv1.3,...
| Schlagworte: | 3-fluoro-4-hydroxy-1,1'-[1,3-phenylenebis(methylene)] ester, benzoic acid |
| Anwendung: | KCa2.3 / KCa3.1 inhibitor |
| CAS | 1867107-62-7 |
| MW: | 414.4 D |
ab 136,00 €
Anti-KCNN3(SK3)
Artikelnummer: ELK-EA301.100
Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Protein function: Forms a voltage-independent potassium channel activated by intracellular calcium (PubMed:31155282, PubMed:20562108). Activation is followed by membrane...
| Schlagworte: | Anti-K3, Anti-SK3, Anti-KCNN3, Anti-SKCa3, Anti-KCa2.3, Anti-SKCa 3, Anti-Small conductance calcium-activated potassium... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
290,00 €
NEU
Anti-SK
Artikelnummer: CSB-PA748713XA01DLU.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-dSK, Anti-CG10706, Anti-Protein SK, Anti-Small conductance calcium-activated potassium channel protein, SK Antibody |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Drosophila melanogaster (Fruit fly) |
ab 1.529,00 €
KCNN3 (human), recombinant protein
Artikelnummer: ABS-PP-11174.20
| Schlagworte: | Small conductance calcium-activated potassium channel protein 3, SK3, SKCa 3, SKCa3, KCa2.3, Recombinant Human KCNN3 Protein |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 15 kD |
ab 90,00 €