Zu "K04856" wurden 18 Artikel gefunden!
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Ethosuximide-d5
Artikelnummer: TGM-TMIH-0224-10mg
Description: Ethosuximide-d5 is a deuterated compound of Ethosuximide. Smiles: [2H]C([2H])([2H])C([2H])([2H])C1(C)CC(=O)NC1=O
| Anwendung: | GC-MS, LC-MS, internal standard, quantification/calcium channel T type blocker, anticonvulsant |
| CAS | 1989660-59-4 |
| MW: | 146.2 D |
ab 400,00 €
Anti-CACNA1I
Artikelnummer: CSB-PA413190.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen....
| Schlagworte: | Anti-CACNA1I, Anti-KIAA1120, Anti-Ca(v)3.3, Anti-Voltage-gated calcium channel subunit alpha Cav3.3,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
126,00 €
Mibefradil (hydrochloride)
Artikelnummer: Cay15037-10
Mibefradil is a general calcium channel blocker that shows modest selectivity for T-type channels over L-type channels (IC50 = 2.7 and 18.6 µM, respectively). It is a potent vasodilator, increasing coronary artery flow with an EC50 value of 54 nM. Mibefradil has minimal negative inotropic effects, supporting its use...
| Schlagworte: | Posicor, Ro 40-5967,... |
| Anwendung: | Calcium channel blocker, Vasodilator |
| CAS | 116666-63-8 |
| MW: | 568.6 D |
ab 145,00 €
Ethosuximide
Artikelnummer: Cay23947-1
Ethosuximide is an anticonvulsant. It increases glucose, fructose-1,6-bisphosphate, and pyruvate levels in rat brain when administered at a dose of 200 mg/kg. Ethosuximide (400 mg/kg) reduces the severity of audiogenic seizures in a rat model of barbiturate withdrawal-induced convulsions. It also inhibits tonic...
| Schlagworte: | CI-366, NSC 64013, 3-ethyl-3-methyl-2,5-pyrrolidinedione |
| Anwendung: | Calcium channel T type blocker, Anticonvulsant |
| CAS | 77-67-8 |
| MW: | 141.2 D |
ab 57,00 €
Flunarizine (hydrochloride)
Artikelnummer: Cay20385-5
Flunarizine is a calcium antagonist that acts as a potent dilator of peripheral vessels without having calcium-blocking actions in the heart. It reduces calcium fluxes in vascular smooth muscle by blocking both voltage-dependent calcium channels and receptor-operated channels. Flunarizine also acts as a dopamine D2...
| Schlagworte: | 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-piperazine, dihydrochloride |
| Anwendung: | Calcium channel T type blocker |
| CAS | 30484-77-6 |
| MW: | 477.4 D |
ab 49,00 €
Penfluridol
Artikelnummer: Cay26071-250
Penfluridol is a first generation typical antipsychotic that binds to dopamine receptors (IC50 = 5.6 nM). It binds to dopamine D4 receptors and also to serotonin (5-HT) receptors (Kis = 31 and 63.1 nM, respectively). Penfluridol (1.25 and 2.5 mg/kg) inhibits stereotypic behavior induced by apomorphine (Cay-16094) in...
| Schlagworte: | R-16341, 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol |
| Anwendung: | Calcium channel T type blocker, Dopamine D4 receptor ligand, Serotonin (5-HT) receptor ligand |
| CAS | 26864-56-2 |
| MW: | 524 D |
ab 52,00 €
Lomerizine (hydrochloride)
Artikelnummer: Cay28374-100
Lomerizine is a voltage-dependent calcium channel blocker that inhibits low- and high-voltage activated calcium currents in rat hippocampal CA1 pyramidal neurons with IC50 values of 1.9 and 4 µM, respectively. It inhibits vasoconstriction induced by potassium chloride, serotonin (5-HT, Cay-14332), or vasopressin in...
| Schlagworte: | KB-2796, 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-piperazine, dihydrochloride |
| Anwendung: | Voltage-dependent calcium channel blocker |
| CAS | 101477-54-7 |
| MW: | 541.5 D |
ab 45,00 €
Z944
Artikelnummer: Cay27679-25
Z944 is an inhibitor of T-type calcium channels (IC50s = 0.050-0.160 µM for the human recombinant voltage-gated calcium (Cav) channels Cav3.1, Cav3.2, and Cav3.3). It is selective for T-type channels over the N-type Cav2.2 channel (IC50 = 11 µM), as well as the rat L-type Cav1.2, human-ether-a-go-go (hERG/Kv11.1)...
| Schlagworte: | 4-[[(3-chloro-5-fluorobenzoyl)amino]methyl]-N-(1,1-dimethylethyl)-1-piperidineacetamide |
| Anwendung: | T-type calcium channel inhibitor |
| CAS | 1199236-64-0 |
| MW: | 383.9 D |
ab 44,00 €
Ethosuximide-d5
Artikelnummer: Cay30759-1
Ethosuximide-d5 is intended for use as an internal standard for the quantification of ethosuximide (Cay-23947) by GC- or LC-MS. Ethosuximide is an anticonvulsant. It increases glucose, fructose-1,6-bisphosphate, and pyruvate levels in rat brain when administered at a dose of 200 mg/kg. Ethosuximide (400 mg/kg)...
| Schlagworte: | CI-366-d5, NSC 64013-d5, 3-(ethyl-1,1,2,2,2-d5)-3-methyl-2,5-pyrrolidinedione |
| Anwendung: | GC-MS, LC-MS, Internal standard, Quantification/calcium channel T type blocker, Anticonvulsant |
| CAS | 1989660-59-4 |
| MW: | 146.2 D |
ab 284,00 €
Anti-CACNA1I
Artikelnummer: G-PACO07169.50
CACNA1I Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human, Mouse, Rat and for use in ELISA, IHC applications. CACNA1I Antibody is a high quality polyclonal antibody for research use only.. Protein function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions...
| Schlagworte: | Anti-CACNA1I, Anti-KIAA1120, Anti-Ca(v)3.3, Anti-Voltage-gated calcium channel subunit alpha Cav3.3,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
341,00 €
ACT-709478
Artikelnummer: Cay25371-25
ACT-709478 is an inhibitor of T-type voltage-gated calcium channel 3.1 (Cav3.1), Cav3.2, and Cav3.3 (IC50s = 6.4, 18, and 7.5 nM, respectively). It is selective for T-type calcium channels over the L-type calcium channel Cav1.2 (IC50 = 2,410 nM). ACT-701478 (10 mg/kg) reduces the cumulative duration of absence-like...
| Schlagworte: | N-[1-[(5-cyano-2-pyridinyl)methyl]-1H-pyrazol-3-yl]-4-[1-(trifluoromethyl)cyclopropyl]-benzeneacetamide |
| Anwendung: | T-type calcium channels inhibitor |
| CAS | 1838651-58-3 |
| MW: | 425.4 D |
ab 67,00 €
Anti-Cav3.3
Artikelnummer: ELK-EA273.50
Voltage-gated Ca2+ channels (CaV), enable the passage of Ca2+ ions in a voltage dependent manner. These heteromeric entities are formed in part by the pore-forming alpha1 subunit which determines the biophysical and pharmacological properties of the channel. Protein function: Voltage-sensitive calcium channels...
| Schlagworte: | Anti-CACNA1I, Anti-Ca(v)3.3, Anti-KIAA1120, Anti-Voltage-gated calcium channel subunit alpha Cav3.3,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
173,00 €