Zu "K04854" wurden 16 Artikel gefunden!
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ACT-709478
Artikelnummer: TGM-T14120-2mg
Description: ACT-709478 is a potent, selective T-type calcium channel blocker that is orally active and capable of penetrating the brain. It is currently utilized in research focusing on generalized epilepsies[1]. Target: Others. Smiles: FC(F)(F)C1(CC1)c1ccc(CC(=O)Nc2ccn(Cc3ccc(cn3)C#N)n2)cc1. References: Bezençon...
| Anwendung: | Targets voltage-dependent calcium channel T type alpha-1G (CACNA1G, CAV3.1) |
| CAS | 1838651-58-3 |
| MW: | 425.41 D |
ab 89,00 €
ZSET1446
Artikelnummer: TGM-T8448-100mg
Description: ZSET1446 (ST-101) is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models. Target: Calcium Channel, AChR. Smiles: O=C1N=C2C=CC=CN2C11Cc2ccccc2C1. References: Yamaguchi Y, et al. Effects of ZSET1446/ST101 on cognitive...
| Schlagworte: | ZSET-1446, ST-101 |
| Anwendung: | Targets voltage-dependent calcium channel T type alpha-1G (CACNA1G, CAV3.1) |
| CAS | 887603-94-3 |
| MW: | 236.27 D |
ab 82,00 €
Anti-CACNA1G
Artikelnummer: CSB-PA796294.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CACNA1G. Antigen Species: Human
| Schlagworte: | Anti-NBR13, Anti-CACNA1G, Anti-Cav3.1c, Anti-KIAA1123, Anti-Voltage-gated calcium channel subunit alpha Cav3.1,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
ab 167,00 €
Mibefradil (hydrochloride)
Artikelnummer: Cay15037-5
Mibefradil is a general calcium channel blocker that shows modest selectivity for T-type channels over L-type channels (IC50 = 2.7 and 18.6 µM, respectively). It is a potent vasodilator, increasing coronary artery flow with an EC50 value of 54 nM. Mibefradil has minimal negative inotropic effects, supporting its use...
| Schlagworte: | Posicor, Ro 40-5967,... |
| Anwendung: | Calcium channel blocker, Vasodilator |
| CAS | 116666-63-8 |
| MW: | 568.6 D |
ab 145,00 €
Penfluridol
Artikelnummer: Cay26071-100
Penfluridol is a first generation typical antipsychotic that binds to dopamine receptors (IC50 = 5.6 nM). It binds to dopamine D4 receptors and also to serotonin (5-HT) receptors (Kis = 31 and 63.1 nM, respectively). Penfluridol (1.25 and 2.5 mg/kg) inhibits stereotypic behavior induced by apomorphine (Cay-16094) in...
| Schlagworte: | R-16341, 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol |
| Anwendung: | Calcium channel T type blocker, Dopamine D4 receptor ligand, Serotonin (5-HT) receptor ligand |
| CAS | 26864-56-2 |
| MW: | 524 D |
ab 52,00 €
Z944
Artikelnummer: Cay27679-5
Z944 is an inhibitor of T-type calcium channels (IC50s = 0.050-0.160 µM for the human recombinant voltage-gated calcium (Cav) channels Cav3.1, Cav3.2, and Cav3.3). It is selective for T-type channels over the N-type Cav2.2 channel (IC50 = 11 µM), as well as the rat L-type Cav1.2, human-ether-a-go-go (hERG/Kv11.1)...
| Schlagworte: | 4-[[(3-chloro-5-fluorobenzoyl)amino]methyl]-N-(1,1-dimethylethyl)-1-piperidineacetamide |
| Anwendung: | T-type calcium channel inhibitor |
| CAS | 1199236-64-0 |
| MW: | 383.9 D |
ab 44,00 €
Flunarizine (hydrochloride)
Artikelnummer: Cay20385-10
Flunarizine is a calcium antagonist that acts as a potent dilator of peripheral vessels without having calcium-blocking actions in the heart. It reduces calcium fluxes in vascular smooth muscle by blocking both voltage-dependent calcium channels and receptor-operated channels. Flunarizine also acts as a dopamine D2...
| Schlagworte: | 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-piperazine, dihydrochloride |
| Anwendung: | Calcium channel T type blocker |
| CAS | 30484-77-6 |
| MW: | 477.4 D |
ab 49,00 €
Lomerizine (hydrochloride)
Artikelnummer: Cay28374-250
Lomerizine is a voltage-dependent calcium channel blocker that inhibits low- and high-voltage activated calcium currents in rat hippocampal CA1 pyramidal neurons with IC50 values of 1.9 and 4 µM, respectively. It inhibits vasoconstriction induced by potassium chloride, serotonin (5-HT, Cay-14332), or vasopressin in...
| Schlagworte: | KB-2796, 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-piperazine, dihydrochloride |
| Anwendung: | Voltage-dependent calcium channel blocker |
| CAS | 101477-54-7 |
| MW: | 541.5 D |
ab 45,00 €
Anti-CACNA1G
Artikelnummer: G-PACO19378.50
CACNA1G Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human, Rat and for use in ELISA, IHC applications. CACNA1G Antibody is a high quality polyclonal antibody for research use only.. Protein function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into...
| Schlagworte: | Anti-NBR13, Anti-CACNA1G, Anti-Cav3.1c, Anti-KIAA1123, Anti-Voltage-gated calcium channel subunit alpha Cav3.1,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
384,00 €
ACT-709478
Artikelnummer: Cay25371-10
ACT-709478 is an inhibitor of T-type voltage-gated calcium channel 3.1 (Cav3.1), Cav3.2, and Cav3.3 (IC50s = 6.4, 18, and 7.5 nM, respectively). It is selective for T-type calcium channels over the L-type calcium channel Cav1.2 (IC50 = 2,410 nM). ACT-701478 (10 mg/kg) reduces the cumulative duration of absence-like...
| Schlagworte: | N-[1-[(5-cyano-2-pyridinyl)methyl]-1H-pyrazol-3-yl]-4-[1-(trifluoromethyl)cyclopropyl]-benzeneacetamide |
| Anwendung: | T-type calcium channels inhibitor |
| CAS | 1838651-58-3 |
| MW: | 425.4 D |
ab 67,00 €
CACNA1G, Human calcium channel, voltage-dependent, T...
Artikelnummer: VHPS-1451
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | CACNA1G, T calcium channel alpha 1G subunit variant 153 |
| Anwendung: | RNA quantification |
44,00 €
Cacna1G, Mouse calcium channel, voltage-dependent, T...
Artikelnummer: VMPS-766
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | Cacna1g |
| Anwendung: | RNA quantification |
44,00 €