Zu "K04841" wurden 44 Artikel gefunden!
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Neoline
Artikelnummer: TGM-T4S0537-10mg
Description: Neoline is an active ingredient of A. venetum root (PA) that ameliorates oxaliplatin-induced peripheral neuropathy in mice.Neoline inhibits Nav1.7 voltage-gated sodium channel currents (VGSC). It can be used as a labeling compound to determine the quality of PA products used in the study of neuropathic...
| Schlagworte: | Bullatine B |
| Anwendung: | Diterpene alkaloid |
| CAS | 466-26-2 |
| MW: | 437.57 D |
ab 38,00 €
PF 05089771 tosylate
Artikelnummer: TGM-T7502-10mg
Description: PF-05089771 is a voltage-gated sodium channel 1.7 (Nav1.7) blocker (IC50: 11, 16, 33, and 20 nM for 5N11S, 5A11L, 5A11S, and 5A11L Nav1.7 splice variants, respectively). It is selective for Nav1.7 over Nav1.1-1.6 and 1.8 channels (IC50: 0.11-25 µM), L-type calcium, and KvLQT and hERG potassium channels...
| Anwendung: | Nav1.7 blocker |
| CAS | 1430806-04-4 |
| MW: | 672.56 D |
ab 56,00 €
Sodium Channel inhibitor 4
Artikelnummer: TGM-T81134-50mg
Description: Sodium Channel Inhibitor 4 is a compound that functions as a sodium channel inhibitor [1]. Target: Sodium Channel. Smiles: O=C(NC1=CC=C(C=C1)S(=O)(=O)NC2=NC=CS2)C(OC3=CC=C(Cl)C=C3)(C)C
| Anwendung: | Sodium Channel inhibitor |
| CAS | 587843-16-1 |
| MW: | 451.95 D |
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Sodium Channel inhibitor 1
Artikelnummer: TGM-T12948-100mg
Description: Sodium Channel inhibitor1 is a novel and selective voltage-gated sodium channel for pain treatment. (IC50 Value of 0.16 uM and 0.41 uM for Na v1.7, V hold-90mV and Na v1.7, V hold-90mV). Target: Others. Smiles: Fc1cccc2C(=O)N(CCc3ccccn3)C(C(=O)NCc3ccc(OC(F)(F)F)cc3)c12. References: Macsari I, et al....
| Anwendung: | Sodium Channel inhibitor |
| CAS | 1198117-23-5 |
| MW: | 473.42 D |
ab 148,00 €
Sodium Channel inhibitor 2
Artikelnummer: TGM-T12951-100mg
Description: Sodium Channel Inhibitor 2 [Sodium Channel inhibitor 2] is a blocker of sodium channels. Target: Sodium Channel. Smiles: C(CN1CCCCC1)N2C(=NC=3C2=CC=CC3)C4=CC(OC5=CC(Cl)=C(Cl)C=C5)=CC=C4. References: Sun Qun, et al. Preparation of aryl-substituted benzimidazoles and their use as sodium channel blockers....
| Anwendung: | Sodium Channel inhibitor |
| CAS | 653573-60-5 |
| MW: | 466.4 D |
ab 1.491,00 €
NaV1.7 inhibitor-1
Artikelnummer: TGM-T12181-100mg
Description: NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7). Target: Sodium Channel. Smiles: CC1(COc2cc(F)c(cc2C2CC2)C(=O)NS(=O)(=O)C2CC2)CCC2(CC2)CC1. References: Sun S, Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of...
| Anwendung: | NaV1.7 inhibitor |
| CAS | 1494585-79-3 |
| MW: | 435.55 D |
ab 104,00 €
Nav1.7 inhibitor
Artikelnummer: TGM-T12184-100mg
Description: Nav1.7 inhibitor is a potent inhibitor of Nav1.7. Target: Others. Smiles: CS(=O)(=O)NC(=O)c1cc(Cl)c(COc2ccc(Cl)c(Cl)c2)cc1F. References: Preparation of sulfonamide derivatives as Nav1.7 inhibitors. Patent WO 2012007868 A2 20120119
| Anwendung: | Nav1.7 inhibitor |
| CAS | 1355631-24-1 |
| MW: | 426.67 D |
ab 193,00 €
Raxatrigine hydrochloride
Artikelnummer: TGM-T14992-100mg
Description: Raxatrigine hydrochloride is a state-dependent sodium channel blocker and a Nav1.7 sodium channel inhibitor. Target: Others. Smiles: Cl.NC(=O)[C@@H]1CC[C@@H](N1)c1ccc(OCc2ccccc2F)cc1. References: Large CH, et al. The efficacy of sodium channel blockers to prevent phencyclidine-induced cognitive...
| Schlagworte: | CNV1014802 (hydrochloride), GSK-1014802 hydrochloride |
| Anwendung: | Targets voltage-gated sodium channel type IX alpha (SCN9A, NAV1.7) |
| CAS | 934240-31-0 |
| MW: | 350.82 D |
ab 86,00 €
Anti-SCN9A
Artikelnummer: CSB-PA003362.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-PN1, Anti-NENA, Anti-hNE-Na, Anti-Peripheral sodium channel 1, Anti-Neuroendocrine sodium channel, Anti-Sodium... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-SCN9A
Artikelnummer: CSB-PA167955.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SCN9A. Antigen Species: Human
| Schlagworte: | Anti-PN1, Anti-NENA, Anti-hNE-Na, Anti-Peripheral sodium channel 1, Anti-Neuroendocrine sodium channel, Anti-Sodium... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
Anti-SCN9A
Artikelnummer: CSB-PA260136.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SCN9A. Antigen Species: Human
| Schlagworte: | Anti-PN1, Anti-NENA, Anti-hNE-Na, Anti-Peripheral sodium channel 1, Anti-Neuroendocrine sodium channel, Anti-Sodium... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
Anti-SCN9A
Artikelnummer: CSB-PA570456.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SCN9A. Antigen Species: Human
| Schlagworte: | Anti-PN1, Anti-NENA, Anti-hNE-Na, Anti-Peripheral sodium channel 1, Anti-Neuroendocrine sodium channel, Anti-Sodium... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €