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Cyphenothrin
Cyphenothrin

Artikelnummer: TGM-T20787-25mg

Description: Cyphenothrin, a synthetic pyrethroid insecticide, is effective against cockroaches that have developed resistance to carbamate and organophosphorous insecticides. Target: Others. Smiles: CC(C)=CC1C(C(=O)OC(C#N)c2cccc(Oc3ccccc3)c2)C1(C)C. References: Driver JH, Ross JH, Holden LR, Selim S, Sharp JK,...
Schlagworte: S2703, S 2703, Gokilaht, S-2703
Anwendung: Targets voltage-gated sodium channel type II alpha (SCN2A, NAV1.2)
CAS 39515-40-7
MW: 375.46 D
1.491,00 €
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Zonisamide-13C2,15N
Zonisamide-13C2,15N

Artikelnummer: TGM-T37847-1mg

Description: Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 µg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous...
Schlagworte: Zonisamide-13C2,15N
Anwendung: GC-MS, LC-MS, internal standard, quantification, antiepileptic
CAS 1188265-58-8
MW: 215.2 D
970,00 €
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Transfluthrin
Transfluthrin

Artikelnummer: TGM-T9751-100mg

Description: Transfluthrin is a volatile pyrethroid insecticide that targets insect voltage-gated sodium channels (VGSC). Target: Others. Smiles: CC1(C)[C@H](C=C(Cl)Cl)[C@@]1(Cc1c(F)c(F)cc(F)c1F)C(O)=O. References: Nolden M, et al. Towards understanding transfluthrin efficacy in a pyrethroid-resistant strain of the...
Anwendung: Targets voltage-gated sodium channel type II alpha (SCN2A, NAV1.2)
CAS 118712-89-3
MW: 371.15 D
ab 50,00 €
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Lamotrigine-d3
Lamotrigine-d3

Artikelnummer: TGM-TMID-0244-1mg

Description: Lamotrigine-d3 is a deuterated compound of Lamotrigine. Lamotrigine has a CAS number of 84057-84-1. Lamotrigine is an Anti-epileptic Agent and Mood Stabilizer. The physiologic effect of lamotrigine is by means of Decreased Central Nervous System Disorganized Electrical Activity. Smiles:...
Anwendung: GC-MS, LC-MS internal standard, quantification, oltage-gated sodium channel inhibitor
CAS 1132746-94-1
MW: 259.11 D
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Lidocaine-d10 (N,N-diethyl-d10)
Lidocaine-d10 (N,N-diethyl-d10)

Artikelnummer: TGM-TMID-0262-1mg

Description: Lidocaine-d10 (N,N-diethyl-d10) is a deuterated compound of Lidocaine. Lidocaine has a CAS number of 137-58-6. Lidocaine is an amide local anesthetic with anti-inflammatory properties in vitro and in vivo. It has this functions perhaps due to an attenuation of intracellular adhesion molecule-1 (ICAM-1),...
Anwendung: GC-MS, LC-MS internal standard, quantification, sodium channel blocker
CAS 851528-09-1
MW: 244.4 D
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Propafenone-d5 HCl
Propafenone-d5 HCl

Artikelnummer: TGM-TMIJ-0501-1mg

Description: Propafenone-d5 HCl is a deuterated compound of Propafenone HCl. Propafenone HCl has a CAS number of 34183-22-7. Propafenone HCl is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias. Smiles:...
Anwendung: GC-MS, LC-MS, internal standard, quantification, sodium channel blocker
CAS 1346605-05-7
MW: 382.94 D
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Phenytoin
Phenytoin

Artikelnummer: Cay24037-250

Phenytoin is an anticonvulsant agent and active metabolite of fosphenytoin (Cay-23889). Phenytoin is formed from fosphenytoin by tissue phosphatases. It inhibits neuronal voltage-gated sodium channels in a voltage-dependent manner. Phenytoin reduces the neuronal firing frequency and decreases the amplitude of...
Schlagworte: 5,5-Diphenylhydantoin, NSC 8722, 5,5-diphenyl-2,4-imidazolidinedione
Anwendung: Voltage-gated sodium channel inhibitor
CAS 57-41-0
MW: 252.3 D
ab 39,00 €
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Anti-SCN2A
Anti-SCN2A

Artikelnummer: CSB-PA902560.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SCN2A. Antigen Species: Human
Schlagworte: Anti-NAC2, Anti-SCN2A, Anti-HBSC II, Anti-Sodium channel protein type 2 subunit alpha, Anti-Sodium channel protein type II...
Anwendung: ELISA, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, rat
ab 163,00 €
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Anti-SCN2A
Anti-SCN2A

Artikelnummer: CSB-PA937791.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SCN2A. Antigen Species: Human
Schlagworte: Anti-NAC2, Anti-SCN2A, Anti-HBSC II, Anti-Sodium channel protein type 2 subunit alpha, Anti-Sodium channel protein type II...
Anwendung: ELISA, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, rat
ab 163,00 €
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Levobupivacaine-d9 (hydrochloride)
Levobupivacaine-d9 (hydrochloride)

Artikelnummer: Cay38904-1

Levobupivacaine-d9 is intended for use as an internal standard for the quantification of levobupivacaine (Cay-31596) by GC- or LC-MS. Levobupivacaine is a sodium channel blocker and local anesthetic, as well as the levorotary stereoisomer of bupivacaine (Cay-16618). It inhibits cardiac sodium channel currents (INa)...
Schlagworte: (S)-(-)-Bupivacaine-d9, 1-butyl-d9-N-(2,6-dimethylphenyl)-(2S)-2-piperidinecarboxamide, monohydrochloride
Anwendung: GC-MS, LC-MS internal standard, quantification, sodium channel blocker, local anesthetic
MW: 333.9 D
ab 82,00 €
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Propafenone (hydrochloride)
Propafenone (hydrochloride)

Artikelnummer: Cay21871-1

Propafenone is a class I antiarrhythmic agent. It inhibits calcium currents (ICa) in isolated guinea pig ventricular myocytes (IC50 = 5 µM), as well as ATP-sensitive potassium currents (IKATP) in isolated rabbit atrial and ventricular monocytes (IC50s = 1.26 and 4.94 µM, respectively). Propafenone also blocks sodium...
Schlagworte: 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone, monohydrochloride
Anwendung: Sodium channel blocker
CAS 34183-22-7
MW: 377.9 D
ab 43,00 €
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Lamotrigine
Lamotrigine

Artikelnummer: Cay15428-10

Lamotrigine is an anticonvulsant. It inhibits voltage-gated sodium channels (Nav) in HEK293 cells expressing recombinant human Nav1.2, Nav1.5, or Nav1.8 (IC50s = 10, 62, and 96 µM, respectively), as well as high voltage-activated calcium currents in isolated rat cortical neurons (IC50 = 12.3 µM), an effect that can...
Schlagworte: BW 430C, Epilepax, Lamictal, LTG, 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine
Anwendung: Voltage-gated sodium channel inhibitor
CAS 84057-84-1
MW: 256.1 D
ab 77,00 €
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