Zu "K04833" wurden 93 Artikel gefunden!
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Tetracaine hydrochloride
Artikelnummer: TGM-T1198-500mg
Description: Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been used for surface and spinal anesthesia. Target: Calcium Channel, Sodium Channel....
| Schlagworte: | Tetracaine HCl, Amethocalne HCl, Amethocaine hydrochloride |
| Anwendung: | Targets voltage-gated sodium channel type I alpha (SCN1A, NAV1.1) |
| CAS | 136-47-0 |
| MW: | 300.824 D |
49,00 €
4-aminobenzoic acid
Artikelnummer: TGM-T1311-1mL
Description: 4-aminobenzoic acid is an organic acid with UV-absorbing and antifibrotic properties. When exposed to light, 4-aminobenzoic acid absorbs UV light and releases excess energy through a photochemical reaction, which may cause DNA damage.4-aminobenzoic acid also increases oxygen uptake at the tissue level...
| Schlagworte: | PABA, Vitamin H1, Vitamin Bx, para-Aminobenzoic acid |
| Anwendung: | Targets voltage-gated sodium channel type I alpha (SCN1A, NAV1.1) |
| CAS | 150-13-0 |
| MW: | 137.14 D |
ab 45,00 €
Disopyramide
Artikelnummer: TGM-T1320-100mg
Description: Disopyramide (Triombrin) is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local...
| Schlagworte: | amidotrizoate sodium, Hypaque sodium, Triombrin |
| Anwendung: | Sodium channel blocker |
| CAS | 3737-09-5 |
| MW: | 339.47 D |
ab 34,00 €
Aprindine hydrochloride
Artikelnummer: TGM-T21373-25mg
Description: Aprindine HCl is a Class 1b antiarrhythmic agent used to manage ventricular and supraventricular arrhythmias. In one study, it delayed atrial fibrillation more than digoxin did. It has shown effectiveness when given orally. Target: Others. Smiles: Cl.C=1C=CC(=CC1)N(CCCN(CC)CC)C2CC=3C=CC=CC3C2....
| Schlagworte: | Aprindine HCl, Aprindina, Fibocil, Aprinidine, Fiboran, Amidonal, Aprindin |
| Anwendung: | Targets voltage-gated sodium channel type I alpha (SCN1A, NAV1.1) |
| CAS | 33237-74-0 |
| MW: | 358.95 D |
ab 1.520,00 €
Flecainide
Artikelnummer: TGM-T21391-50mg
Description: Flecainide acetate is a class Ic antiarrhythmic agent, it is used to treat a variety of cardiac arrhythmias including paroxysmal atrial fibrillation, paroxysmal supraventricular tachycardia, and ventricular tachycardia. It works by regulating the flow of sodium in the heart, causing prolongation of the...
| Schlagworte: | Flecainida, Apocard, Tambocor, Flecainidum |
| Anwendung: | Targets voltage-gated sodium channel type I alpha (SCN1A, NAV1.1) |
| CAS | 54143-55-4 |
| MW: | 414.34 D |
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Disopyramide phosphate
Artikelnummer: TGM-T21424-25mg
Description: Disopyramide, a sodium channel blocker in the Class of 1a anti-arrhythmic agent, is used in the treatment of Ventricular Tachycardia. Disopyramide has a negative inotropic effect on the ventricular myocardium, resulting in a significant decrease in contractility. Target: Others. Smiles:...
| Schlagworte: | SC-13957, SC 13957, SC13957 |
| Anwendung: | Targets voltage-gated sodium channel type I alpha (SCN1A, NAV1.1) |
| CAS | 22059-60-5 |
| MW: | 437.47 D |
ab 1.520,00 €
Mephenytoin
Artikelnummer: TGM-T21425-1mg
Description: Mephenytoin (Phenantoin) is an anticonvulsant and a substrate of CYP2C19 and CYP2B6. Target: P450. Smiles: C(C)C1(C(=O)N(C)C(=O)N1)C2=CC=CC=C2. References: Vijayabhaskar V, Srivastava P, Rajagopal S. Breaking the sensitivity limitations of cytochrome P450 oxidation product: dansyl chloride...
| Schlagworte: | Methylphenetoin, Methoin, Insulton, Phenantoin, Mesantoin |
| Anwendung: | Targets voltage-gated sodium channel type I alpha (SCN1A, NAV1.1) |
| CAS | 50-12-4 |
| MW: | 218.25 D |
ab 37,00 €
Mexiletine
Artikelnummer: TGM-T21427-25mg
Description: Mexiletine is a non-selective voltage-gated sodium channel blocker. It is a medicine in the class of IB anti-arrhythmic. Mexiletine may also be used in patients experiencing refractory pain and is effective to treat muscle stiffness resulting from myotonic dystrophy or non-dystrophic myotonias. Target:...
| Schlagworte: | KO 1173, KO1173, KO-1173, Mexitil, Mexiletene |
| Anwendung: | Targets voltage-gated sodium channel type I alpha (SCN1A, NAV1.1) |
| CAS | 31828-71-4 |
| MW: | 179.26 D |
ab 1.520,00 €
Transcainide
Artikelnummer: TGM-T26287-100mg
Description: Transcainide(R 54718), a new lidocaine analog, is an orally active antiarrhythmic agent.Transcainide blocks the open state of BTX-activated sodium channels in bovine heart and rat skeletal muscle. Target: Sodium Channel. Smiles: C(NC1=C(C)C=CC=C1C)(=O)C2(N(C)C)CCN(CC2)[C@H]3[C@H](O)CCCC3. References:...
| Schlagworte: | R-54718, R54718, R 54718 |
| Anwendung: | Targets voltage-gated sodium channel type I alpha (SCN1A, NAV1.1) |
| CAS | 88296-62-2 |
| MW: | 373.53 D |
ab 266,00 €
Indecainide hydrochloride
Artikelnummer: TGM-T32155L-100mg
Description: Indecainide hydrochloride is a cardiac depressant. Target: Others. Smiles: Cl.O=C(N)C1(C=2C=CC=CC2C=3C=CC=CC31)CCCNC(C)C. References: Giardina EV, Saroff AL, Schneider M. Effect of indecainide in patients with left ventricular dysfunction. Clin Pharmacol Ther. 1990 Nov,48(5):582-9. PubMed PMID: 2225716.
| Anwendung: | Targets voltage-gated sodium channel type I alpha (SCN1A, NAV1.1) |
| CAS | 73681-12-6 |
| MW: | 344.88 D |
ab 1.520,00 €
Eslicarbazepine Acetate
Artikelnummer: TGM-T3285-100mg
Description: Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy. Target: Beta-Secretase, Sodium Channel. Smiles:...
| Schlagworte: | Zebinix, BIA 2-093, Aptiom, Exalief, Stedesa |
| Anwendung: | Targets voltage-gated sodium channel type I alpha (SCN1A, NAV1.1) |
| CAS | 236395-14-5 |
| MW: | 296.32 D |
ab 33,00 €
Eslicarbazepine
Artikelnummer: TGM-T3285L-100mg
Description: Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures. Target: Beta-Secretase, Sodium Channel. Smiles: NC(=O)N1c2ccccc2C[C@H](O)c2ccccc12. References: Doeser A, Soares-da-Silva P, Beck H, Uebachs M. The effects of eslicarbazepine on persistent Na+ current...
| Schlagworte: | Erelib, Stedesa, BIA 2-194, Pazzul, EC 810-248-9 |
| Anwendung: | Targets voltage-gated sodium channel type I alpha (SCN1A, NAV1.1) |
| CAS | 104746-04-5 |
| MW: | 254.28 D |
ab 42,00 €