Zu "K04824" wurden 30 Artikel gefunden!
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Triamterene D5
Artikelnummer: TGM-T19591-1mg
Description: Triamterene D5 is a deuterium-labeled Triamterene and can block epithelial Na+ channel (ENaC) in a voltage-dependent manner, used as a mild diuretic. Smiles: [2H]c1c([2H])c([2H])c(c([2H])c1[2H])-c1nc2c(N)nc(N)nc2nc1N
| Anwendung: | GC-MS, LC-MS internal standard, quantification, epithelial sodium channel blocker |
| CAS | 1189922-23-3 |
| MW: | 258.29 D |
ab 228,00 €
Anti-SCNN1A
Artikelnummer: CSB-PA435775.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SCNN1A. Antigen Species: Human
| Schlagworte: | Anti-SCNN1, Anti-ENaCA, Anti-SCNEA, Anti-SCNN1A, Anti-Alpha-ENaC, Anti-Alpha-NaCH, Anti-Epithelial Na(+) channel subunit... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Triamterene
Artikelnummer: Cay21242-1
Triamterene is an inhibitor of the epithelial sodium channel (ENaC, IC50 = 4.5 µM for the rat channel). In vivo, triamterene (0.5-32 mg/animal) enhances sodium secretion and decreases potassium secretion in adrenalectomized rats. Formulations containing triamterene have been used in the treatment of edema. This...
| Schlagworte: | 2,4,7-Triamino-6-phenylpteridine, NSC 77625, SKF 8542, 6-phenyl-2,4,7-pteridinetriamine |
| Anwendung: | Epithelial sodium channel blocker |
| CAS | 396-01-0 |
| MW: | 253.3 D |
ab 28,00 €
Amiloride (hydrochloride) (hydrate)
Artikelnummer: Cay14409-5
Amiloride is a potassium-sparing diuretic. It is an inhibitor of the epithelial sodium channel (ENaC, K0.5 = 2.6 µM for recombinant deltaENaC expressed in X. laevis oocytes). It inhibits sodium transport from bovine kidney cortex membrane vesicles with an IC50 value of 0.4 µM. Amiloride inhibits the urokinase-type...
| Schlagworte: | MK-870, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-2-pyrazinecarboxamide, monohydrochloride hydrate |
| Anwendung: | Metabolic studies |
| MW: | 266.1 D |
ab 55,00 €
Amiloride (hydrochloride)
Artikelnummer: Cay26295-1
Amiloride (hydrochloride) (Cay-26295) is an analytical reference standard categorized as a diuretic. Formulations containing diuretics, including amiloride, have been misused in sports for weight reduction and as masking agents. This product is intended for use in analytical forensic applications. This product is...
| Schlagworte: | MK-870, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-2-pyrazinecarboxamide, monohydrochloride |
| Anwendung: | Analytical reference standard, diuretic, epithelial sodium channel blocker |
| CAS | 2016-88-8 |
| MW: | 266.1 D |
ab 61,00 €
Anti-ENaC Alpha
Artikelnummer: ARG22200.50
Protein function: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells (PubMed:8382172). Plays an essential role in electrolyte and blood...
| Schlagworte: | Anti-SCNEA, Anti-Renac, Anti-Scnn1a, Anti-Alpha-NaCH, Anti-Alpha-ENaC, Anti-Epithelial Na(+) channel subunit alpha,... |
| Anwendung: | WB, IHC, ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat, Xenopus laevis |
551,00 €
Anti-SCNN1A
Artikelnummer: NSJ-RQ4301
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The SCNN1A gene encodes the alpha subunit of the epithelial sodium channel (ENaC), a constitutively active channel that allows the flow of sodium ions from the lumen into epithelial cells across the apical cell membrane. The ENaC channel, which is regulated by...
| Schlagworte: | Anti-SCNN1, Anti-ENaCA, Anti-SCNEA, Anti-SCNN1A, Anti-Alpha-NaCH, Anti-Alpha-ENaC, Anti-Epithelial Na(+) channel subunit... |
| Anwendung: | WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
772,00 €
Benzamil (hydrochloride)
Artikelnummer: Cay14313-10
Benzamil is a derivative of amiloride (Cay-14409). Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane vesicles. It is also an inhibitor of the Na+/Ca2+ exchanger (NCX) that inhibits the cytosolic calcium...
| Schlagworte: | 3,5-diamino-6-chloro-N-[imino[(phenylmethyl)amino]methyl]-2-pyrazinecarboxamide, monohydrochloride |
| Anwendung: | Epithelial sodium channel (ENaC) blocker |
| CAS | 161804-20-2 |
| MW: | 356.2 D |
ab 59,00 €
Anti-SCNN1A
Artikelnummer: E-AB-67674.120
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with...
| Schlagworte: | Anti-SCNN1, Anti-SCNEA, Anti-ENaCA, Anti-SCNN1A, Anti-Alpha-NaCH, Anti-Alpha-ENaC, Anti-Epithelial Na(+) channel subunit... |
| Anwendung: | IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 243,00 €
Triamterene-d5
Artikelnummer: Cay33815-1
Triamterene-d5 is intended for use as an internal standard for the quantification of triamterene (Cay-21242) by GC- or LC-MS. Triamterene is an inhibitor of the epithelial sodium channel (ENaC, IC50 = 4.5 µM for the rat channel). In vivo, triamterene (0.5-32 mg/animal) enhances sodium secretion and decreases...
| Schlagworte: | 2,4,7-Triamino-6-phenylpteridine-d5, 6-phenyl-d5-2,4,7-pteridinetriamine |
| Anwendung: | GC-MS, LC-MS internal standard, quantification, epithelial sodium channel blocker |
| CAS | 1189922-23-3 |
| MW: | 258.3 D |
ab 85,00 €
Anti-SCNN1A
Artikelnummer: ATA-HPA012743.100
Protein function: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis,...
| Schlagworte: | Anti-ENaCA, Anti-SCNN1, Anti-SCNEA, Anti-SCNN1A, Anti-Alpha-ENaC, Anti-Alpha-NaCH, Anti-Epithelial Na(+) channel subunit... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 320,00 €
Triamterene
Artikelnummer: Cay22486-1
Triamterene (Cay-22486) is an analytical reference standard that is categorized as a pteridine. Triamterene is an inhibitor of the epithelial sodium channel (ENaC) that increases renal sodium excretion and decreases potassium excretion. It inhibits rat ENaC with an IC50 value of 4.5 µM. Diuretics, including...
| Schlagworte: | 2,4,7-Triamino-6-phenylpteridine, NSC 77625, SKF 8542, 6-phenyl-2,4,7-pteridinetriamine |
| Anwendung: | Analytical reference standard, pteridine, diuretic, ENaC inhibitor |
| CAS | 396-01-0 |
| MW: | 253.3 D |
ab 61,00 €