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Zu "K04819" wurden 109 Artikel gefunden!
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Artikelnummer: TGM-T13308-1mg
Description: Vortioxetine D8 is a deuterium-labeled Vortioxetine, a compound that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptors and SERT with [Kis: 15 nM, 33 nM, 3.7 nM, 19 nM, and 1.6 nM, respectively]. Smiles: S(C1=C(C=CC=C1)N2C(C(NC(C2([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])C3=C(C)C=C(C)C=C3. References:...
Schlagworte: | Lu AA 21004 D8 |
Anwendung: | GC-MS, LC-MS, internal standard, quantification, serotonin receptor antagonist |
CAS | 2140316-62-5 |
MW: | 306.5 D |
873,00 €
Artikelnummer: TGM-T14526-10mg
Description: Bemesetron (MDL 72222) is a selective 5-HT3 antagonist (IC50 = 0.33 nM) that exhibits neuroprotective effects. Target: 5-HT Receptor. Smiles: CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc(Cl)cc(Cl)c1. References: Peters JA, et al. An electrophysiological investigation of the properties of 5-HT3 receptors of...
Schlagworte: | TROPANYL 3,5-DICHLOROBENZOATE, 3-TROPANYL-3,5-DICHLOROBENZOATE, MDL 72222 |
Anwendung: | Targets 5-hydroxytryptamine receptor 3 (HTR3) |
CAS | 40796-97-2 |
MW: | 314.21 D |
ab 50,00 €
Artikelnummer: TGM-T1478-100mg
Description: Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties. Target: 5-HT Receptor....
Schlagworte: | GR 38032, Ondansetron hydrochloride, SN 307, NSC 665799 |
Anwendung: | Targets 5-hydroxytryptamine receptor 3 (HTR3) |
CAS | 103639-04-9 |
MW: | 365.86 D |
ab 36,00 €
Artikelnummer: TGM-T21235-200mg
Description: Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only. Target: Others. Smiles: Cc1nc[nH]c1CN1CCc2c(C1=O)c1ccccc1n2C. References: Motavallian A, Minaiyan M, Rabbani M, Mahzouni P, Andalib S. Anti-inflammatory effects of...
Schlagworte: | GR 68755, GR-68755, Lotronex, GR68755 |
Anwendung: | Targets 5-hydroxytryptamine receptor 3 (HTR3) |
CAS | 122852-42-0 |
MW: | 294.36 D |
1.175,00 €
Artikelnummer: TGM-T27607-100mg
Description: Indisetron Dihydrochloride is a 5-HT(3) and 5-HT(4) receptor antagonist. Indisetron reduces 2-methyl-5-serotonin (HT)-induced bradycardia. Target: Others. Smiles: Cl.[H][C@]12C[C@@H](C[C@]([H])(CN(C)C1)N2C)NC(=O)c1n[nH]c2ccccc12 , TLB:14:4:12:8.9.11,10:9:12:4.3.5, . References: Tsukagoshi S, Tokyo...
Schlagworte: | Sinseron, N3389T, N-3389T, N 3389T |
Anwendung: | Targets 5-hydroxytryptamine receptor 3 (HTR3) |
CAS | 160472-97-9 |
MW: | 349.86 D |
ab 1.491,00 €
Artikelnummer: TGM-T27020-1mg
Description: Cilansetron is an effective and selective 5-HT3 receptor antagonist that can be used for related diseases caused by colitis. Target: 5-HT Receptor. Smiles: O=C1C=2C=3C=4N(C2CC[C@@H]1CN5C(C)=NC=C5)CCCC4C=CC3. References: Chey WD, Cash BD. Cilansetron: a new serotonergic agent for the irritable bowel...
Schlagworte: | KC-9946, KC9946, DU-123265, DU123265 |
Anwendung: | Targets 5-hydroxytryptamine receptor 3 (HTR3) |
CAS | 120635-74-7 |
MW: | 319.4 D |
ab 190,00 €
Artikelnummer: TGM-T26650-25mg
Description: Arazasetron is an antiemetic which acts as a 5-HT3 receptor antagonist, pKi = 9.27. Target: Others. Smiles: O=C(NC1CN2CCC1CC2)C3=CC(Cl)=CC4=C3OCC(=O)N4C. References: Fang BX, Chen FC, Zhu D, Guo J, Wang LH. Stability of azasetron-dexamethasone mixture for chemotherapy-induced nausea and vomiting...
Schlagworte: | WR85915, Y25130, WR 85915, Y-25130, WR-85915 |
Anwendung: | Targets 5-hydroxytryptamine receptor 3 (HTR3) |
CAS | 123040-69-7 |
MW: | 349.81 D |
1.491,00 €
Artikelnummer: TGM-T37246-10mg
Description: Palonosetron N-oxide is a metabolite of the serotonin (5-HT) receptor subtype 5-HT3antagonist palonosetron .1It is also a potential impurity in palonosetron preparations.2Palonosetron N-oxide is a degradation product formed by exposure to oxidative stress. Target: Others. Smiles:...
Anwendung: | Palonosetron metabolite |
CAS | 813425-83-1 |
MW: | 312.413 D |
ab 237,00 €
Artikelnummer: TGM-T71588-100mg
Description: Batanopride is a antiemetic 5-HT3 receptor antagonist. Target: Others
Anwendung: | Targets 5-hydroxytryptamine receptor 3 (HTR3) |
CAS | 102670-59-7 |
MW: | 392.321 D |
ab 1.491,00 €
Artikelnummer: TGM-T71792-100mg
Description: Quipazine maleate is a selective 5-HT receptor agonist that promotes the proliferation and apoptosis of human hepatocyte strain of L-02 strain and could also exert an excitatory effect on raphe neurons via stimulation of 5-HT2A receptors. Like quipazine, quipazine derivatives produce contracture of...
Anwendung: | Targets 5-hydroxytryptamine receptor 3 (HTR3) |
CAS | 5786-68-5 |
MW: | 329.356 D |
ab 1.491,00 €
Artikelnummer: TGM-T8445-100mg
Description: PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor. Target: Apoptosis, 5-HT Receptor. Smiles: C(Sc1ncnc2nc[nH]c12)c1cccc2ccccc12. References: Trattnig S M , Harpsoe K , Thygesen S B , et al. Discovery of a Novel Allosteric Modulator of 5-HT3...
Schlagworte: | PU-02, 6-[(1-Naphthalenylmethyl)thio]-9H-purine |
Anwendung: | 5-hydroxytryptamine receptor 3A (5-HT3-A) antagonist |
CAS | 313984-77-9 |
MW: | 292.36 D |
ab 54,00 €
Artikelnummer: TGM-TMIJ-0499-1mg
Description: Granisetron-d3 is a deuterated compound of Granisetron. Granisetron has a CAS number of 109889-09-0. Granisetron, a serotonin receptor (5HT-3 selective) antagonist, is used as an antinauseant and antiemetic for cancer chemotherapy. Smiles: C(N1N=C(C(=O)NC2CC3N(C)C(C2)CCC3)C2=CC=CC=C21)([2H])([2H])[2H]
Anwendung: | GC-MS, LC-MS, quantification internal standard, 5-HT3 receptor antagonist |
CAS | 1224925-76-1 |
MW: | 315.43 D |
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