Zu "K04809" wurden 40 Artikel gefunden!
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Neuronal acetylcholine receptor subunit alpha-7 (CHRNA7),...
Artikelnummer: CSB-EP005393HUa0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 23-230aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: GEFQRKLYKE LVKNYNPLER PVANDSQPLT VYFSLSLLQI MDVDEKNQVL TTNIWLQMSW TDHYLQWNVS EYPGVKTVRF PDGQIWKPDI LLYNSADERF DATFHTNVLV NSSGHCQYLP PGIFKSSCYI DVRWFPFDVQ...
| Schlagworte: | CHRNA7, NACHRA7, Neuronal acetylcholine receptor subunit alpha-7, Recombinant Human Neuronal acetylcholine receptor... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 30.4 kD |
ab 283,00 €
Anti-CHRNA7
Artikelnummer: CSB-PA969473.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CHRNA7. Antigen Species: Human
| Schlagworte: | Anti-CHRNA7, Anti-NACHRA7, Anti-Neuronal acetylcholine receptor subunit alpha-7, 7nAChR antibody, a7 nicotinic... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
B-973B
Artikelnummer: Cay38790-1
B-973B is an allosteric agonist and positive allosteric modulator (ago-PAM) of alpha7 nicotinic acetylcholine receptors (nAChRs). It enhances ACh-induced activation in a two-electrode voltage-clamp assay using Xenopus oocytes expressing the human alpha7 nAChR when used at a concentration of 10 µM. B-973B (10 mg/kg)...
| Schlagworte: | (-)-(S)-B-973B, 3,4-difluoro-N-[(1S)-1-[6-[4-(2-pyridinyl)-1-piperazinyl]-2-pyrazinyl]ethyl]-benzenepropanamide |
| Anwendung: | alpha7 nAChR ago-PAM (allosteric agonist / positive allosteric modulator) |
| CAS | 2244989-34-0 |
| MW: | 452.5 D |
ab 47,00 €
CCMI
Artikelnummer: Cay37571-25
CCMI is a positive allosteric modulator (PAM) of alpha7 nicotinic acetylcholine receptors (nAChRs). It enhances ACh-, nicotine-, or choline-induced currents in Xenopus oocytes expressing recombinant human alpha7 nAChRs (EC50s = 0.7, 0.6, and 0.5 µM, respectively). In vivo, CCMI (0.3 and 1 mg/kg, i.v.) improves...
| Schlagworte: | AVL-3288, XY-4083, N-(4-chlorophenyl)-alpha-[[(4-chlorophenyl)amino]methylene]-3-methyl-5-isoxazoleacetamide |
| Anwendung: | Alpha7 nAChR positive allosteric modulator |
| CAS | 917837-54-8 |
| MW: | 388.3 D |
ab 35,00 €
(±)-Anatoxin A (fumarate)
Artikelnummer: Cay14609-1
(±)-Anatoxin A is a bicyclic amine isolated from the blue-green alga A. aquae that displays high affinity for nicotinic acetylcholine receptors (Kd = 0.1-0.2 µM). It binds alpha4beta2- and alpha7-type nicotinic receptors with Ki values of 1.3 nM and 1.8 µM, respectively, and stimulates [3H]-dopamine release from...
| Schlagworte: | 1-(9-azabicyclo[4.2.1]non-2-en-2-yl)-ethanone, 2-butenedioate |
| Anwendung: | Neuronal nicotinic acetylcholine receptor agonist |
| CAS | 1219922-30-1 |
| MW: | 281.3 D |
327,00 €
Human CHRNa7 (Cholinergic Receptor, Nicotinic, Alpha 7)...
Artikelnummer: ELK-ELK4287.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CHRNa7. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CHRNa7....
| Schlagworte: | CHRNA7, NACHRA7, Neuronal acetylcholine receptor subunit alpha-7 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
GTS-21 (hydrochloride)
Artikelnummer: Cay21570-50
GTS-21 is an agonist of alpha7-containing nicotinic acetylcholine receptors (nAChRs) that, at a concentration of 100 µM, activates human alpha7-containing nAChRs expressed in Xenopus oocytes to 60% of the levels generated by endogenous ligand acetylcholine. It is selective for alpha7-containing nAChRs, having no...
| Schlagworte: | DMXB-A, (3E)-3-[(2,4-dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-bipyridine, dihydrochloride |
| Anwendung: | Partial alpha7 nicotinic acetylcholine receptor agonist |
| CAS | 156223-05-1 |
| MW: | 381.3 D |
ab 86,00 €
(±)-Nornicotine
Artikelnummer: Cay20505-250
(±)-Nornicotine is an active metabolite of nicotine (Cay-16535) and a nicotinic acetylcholine receptor (nAChR) agonist. It induces currents in Xenopus oocytes expressing human alpha7 nAChRs or alpha6 subunit-containing nAChRs (EC50s = 17 and 3.7 µM, respectively). (±)-Nornicotine promotes cell migration and...
| Schlagworte: | (R,S)-Nornicotine, DL-Nornicotine, 3-(2-pyrrolidinyl)-pyridine |
| Anwendung: | nAChR agonist |
| CAS | 5746-86-1 |
| MW: | 148.2 D |
ab 50,00 €
Methyllycaconitine (citrate)
Artikelnummer: Cay21398-5
Methyllycaconitine (MLA) is an antagonist of alpha7-containing neuronal nicotinic acetylcholine receptors (nAChRs, Ki = 1.4 nM). It is less effective at other nAChRs. MLA is used to selectively evaluate the role of alpha7-containing nAChRs in signaling pathways.Formal Name:...
| Schlagworte: | MLA,... |
| Anwendung: | nAChR (CHRNA7) antagonist |
| CAS | 351344-10-0 |
| MW: | 874.9 D |
ab 46,00 €
NS 1738
Artikelnummer: Cay21018-5
NS 1738 is a positive allosteric modulator of the alpha7-containing neuronal nicotinic acetylcholine receptors (nAChRs). When applied in the presence of ACh, NS 1738 increases the peak amplitude of the current flowing through alpha7-containing nAChRs (EC50 = 3.4 µM). NS 1738 displays no substantial activity for...
| Schlagworte: | NSC 213859, N-(5-chloro-2-hydroxyphenyl)-N'-[2-chloro-5-(trifluoromethyl)phenyl]-urea |
| Anwendung: | Positive allosteric nAChR (CHRNA7) modulator |
| CAS | 501684-93-1 |
| MW: | 365.1 D |
ab 43,00 €
Anti-CHRNA7
Artikelnummer: NSJ-R34630-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Cholinergic receptor, nicotinic, alpha 7 Protein function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of...
| Schlagworte: | Anti-CHRNA7, Anti-NACHRA7, Anti-Neuronal acetylcholine receptor subunit alpha-7, CHRNA7 Antibody |
| Anwendung: | IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Anti-CHRFAM7A
Artikelnummer: E-AB-12583.120
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a...
| Schlagworte: | Anti-CHRNA7, Anti-NACHRA7, Anti-Neuronal acetylcholine receptor subunit alpha-7, CHRFAM7A Polyclonal Antibody |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €