Zu "K04806" wurden 35 Artikel gefunden!
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Anti-CHRNA4
Artikelnummer: CSB-PA215866.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CHRNA4. Antigen Species: Human
| Schlagworte: | Anti-CHRNA4, Anti-NACRA4, Anti-Neuronal acetylcholine receptor subunit alpha-4, A4 nicotinic receptor antibody,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
Anti-CHRNA4
Artikelnummer: CSB-PA938221.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CHRNA4. Antigen Species: Human
| Schlagworte: | Anti-CHRNA4, Anti-NACRA4, Anti-Neuronal acetylcholine receptor subunit alpha-4, A4 nicotinic receptor antibody,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
(±)-Anabasine (hydrochloride)
Artikelnummer: Cay18206-500
(±)-Anabasine is an alkaloid that has been found as a minor component in tobacco (Nicotiana). It is a full agonist of nicotinic acetylcholine receptors (nAChRs) that induces depolarization of TE 671 cells endogenously expressing human fetal muscle-type nAChRs (EC50 = 10.1 µM) but not SH-SY5Y cells that primarily...
| Schlagworte: | 3-(piperidin-2-yl)pyridine, hydrochloride |
| Anwendung: | Nicotinic acetylcholine receptor alpha4beta2 subtype ligand |
| MW: | 162.2 D |
ab 43,00 €
Varenicline-d4
Artikelnummer: Cay26102-1
Varenicline-d4 is intended for use as an internal standard for the quantification of varenicline (Cay-15030) by GC- or LC-MS. Varenicline is a full agonist of alpha7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs, EC50 = 18 µM) and a partial agonist of alpha4beta2 subunit-containing nAChRs...
| Schlagworte: | 7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline-7,7,9,9-d4 |
| Anwendung: | GC-MS, LC-MS, Internal standard, Alpha4beta2 neuronal nicotinic acetylcholine receptor agonist |
| CAS | 2183239-01-0 |
| MW: | 215.3 D |
ab 125,00 €
Varenicline (tartrate)
Artikelnummer: Cay15030-10
Varenicline is a full agonist of alpha7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs, EC50 = 18 µM) and a partial agonist of alpha4beta2 subunit-containing nAChRs (EC50 = 2.3 µM). Formulations containing varenicline have been used as aids in smoking cessation.Formal Name:...
| Schlagworte: | CP 526,555-18, 7,8,9,10-tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine-(2R,3R)-dihydroxybutanedioate |
| Anwendung: | alpha4beta2 neuronal nicotinic acetylcholine receptor agonist |
| CAS | 375815-87-5 |
| MW: | 361.4 D |
ab 142,00 €
(-)-Nicotine (tartrate)
Artikelnummer: Cay20887-1
(-)-Nicotine is an alkaloid that has been found in tobacco. It is an agonist at neuronal nicotinic acetylcholine receptors (nAChRs) and binds to alpha3beta4 and alpha4beta2 subunit-containing nAChRs with Ki values of 481 and 11.1 nM, respectively. Chronic exposure to (-)-nicotine results in increased expression of...
| Schlagworte: | NSC 97238, 3-[(2S)-1-methyl-2-pyrrolidinyl]-pyridine (2R,3R)-2,3-dihydroxybutanedioate |
| Anwendung: | nAChR agonist |
| CAS | 65-31-6 |
| MW: | 462.4 D |
ab 50,00 €
ABT-594 (hydrochloride)
Artikelnummer: Cay22822-1
ABT-594 is a potent agonist of neuronal alpha4beta2 subunit-containing nicotinic acetylcholine receptors (nAChRs, Ki = 37 pM in a radioligand binding assay). It is selective for neuronal nAChRs over neuromuscular alpha1beta1deltagamma subunit-containing nAChRs (Ki = 10,000 nM), alpha1B-, alpha2B-, and alpha2C-...
| Schlagworte: | Ebanicline, Tebanicline, 5-[(2R)-2-azetidinylmethoxy]-2-chloro-pyridine, monohydrochloride |
| Anwendung: | Nicotinic acetylcholine receptor partial agonist |
| CAS | 203564-54-9 |
| MW: | 235.1 D |
ab 50,00 €
Anti-CHRNA4 (aa29-43), Internal
Artikelnummer: ARG64681.100
Protein function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions. [The UniProt Consortium]
| Schlagworte: | Anti-CHRNA4, Anti-NACRA4, Anti-Neuronal acetylcholine receptor subunit alpha-4 |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, rat |
784,00 €
Anti-CHRNA4
Artikelnummer: NSJ-R34316-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Cholinergic receptor, nicotinic, alpha 4, BFNC, EBN Protein function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to...
| Schlagworte: | Anti-CHRNA4, Anti-NACRA4, Anti-Neuronal acetylcholine receptor subunit alpha-4, CHRNA4 Antibody |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, rat |
755,00 €
Chlorisondamine (iodide)
Artikelnummer: Cay20119-5
Chlorisondamine is an antagonist of nicotinic acetylcholine receptors (nAChRs, IC50 = 1.8 µM in rat striatal synaptosomes) and a ganglion blocker. It decreases dopamine release induced by nicotine (Cay-16535, Cay-20887) in a dose-dependent manner in rat striatal synaptosomes at concentrations ranging from 0-100 µM....
| Schlagworte: | 4,5,6,7-tetrachloro-2,3-dihydro-2-methyl-2-[2-(trimethylammonio)ethyl]-1H-isoindolium, diiodide |
| Anwendung: | Nicotinic acetylcholine receptor antagonist |
| CAS | 96750-66-2 |
| MW: | 611.9 D |
ab 50,00 €
Varenicline Tartrate
Artikelnummer: LKT-V0369.100
alpha7 and beta4 nAChR agonist, alpha4beta2 and alpha6beta2 nAChR partial agonist.
| Anwendung: | alpha-4 beta-2 nicotinic receptor partial agonist |
| CAS | 375815-87-5 |
| MW: | 361.35 D |
ab 111,00 €
Cisatracurium (besylate)
Artikelnummer: Cay22959-25
Cisatracurium is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs) and non-depolarizing muscle relaxant. It inhibits stimulation of human adult muscle nAChRs by acetylcholine (Cay-23829) with an IC50 value of 10 nM. It also inhibits mouse nAChRs with IC50 values of 54 and 115 nM for adult and...
| Schlagworte: | (1R,1'R,2R,2'R)-2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydr... |
| Anwendung: | nAChR competitive antagonist |
| CAS | 96946-42-8 |
| MW: | 1243.5 D |
ab 125,00 €