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Zu "K04734" wurden 114 Artikel gefunden!
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Artikelnummer: ELK-ELK2219.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human IkBa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human IkBa. Next,...
Schlagworte: | IKBA, NFKBIA, IkB-alpha, IkappaBalpha, I-kappa-B-alpha, NF-kappa-B inhibitor alpha, Major histocompatibility complex... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: ELK-ELK4340.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse IkBa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse IkBa. Next,...
Schlagworte: | Ikba, Nfkbia, IkB-alpha, IkappaBalpha, I-kappa-B-alpha, NF-kappa-B inhibitor alpha |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: ELK-EA213.100
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IkappaBalpha phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory...
Schlagworte: | Anti-IKBA, Anti-NFKBIA, Anti-IkB-alpha, Anti-IkappaBalpha, Anti-I-kappa-B-alpha, Anti-NF-kappa-B inhibitor alpha,... |
Anwendung: | WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
283,00 €
Artikelnummer: ELK-EA339.50
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IkappaBalpha phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory...
Schlagworte: | Anti-IKBA, Anti-NFKBIA, Anti-IkB-alpha, Anti-IkappaBalpha, Anti-I-kappa-B-alpha, Anti-NF-kappa-B inhibitor alpha,... |
Anwendung: | WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
169,00 €
Artikelnummer: Cay10010266-5
The transcription factor NF-kappaB plays a key role in regulating over 150 target genes including the expression of inflammatory cytokines, chemokines, immunoreceptors, and cell adhesion molecules. In the cytoplasm, inactive NF-kappaB complexes are bound to an inhibitor IkappaB. However in response to certain...
Schlagworte: | 3-[(4-methylphenyl)sulfonyl]-(2E)-propenenitrile |
Anwendung: | NF-kappaB activation inhibitor |
CAS | 19542-67-7 |
MW: | 207.3 D |
ab 66,00 €
Artikelnummer: Cay14795-5
In the classical pathway of NF-kappaB activation, phosphorylation of the inhibitor of NF-kappaB (IkappaBalpha) releases the inhibitor from NF-kappaB, allowing IkappaBalpha degradation and NF-kappaB activation and nuclear import. BAY 11-7085 is an irreversible inhibitor of IkappaBalpha phosphorylation, preventing...
Schlagworte: | 3-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]-2E-propenenitrile |
Anwendung: | Irreversible IkappaBalpha phosphorylation inhibitor |
CAS | 196309-76-9 |
MW: | 249.3 D |
ab 77,00 €
Artikelnummer: AG-CR1-0013-M010
IkappaBalpha kinase inhibitor, NF-kappaB inhibitor, Potential anti-inflammatory agent, Apoptosis inducer, Inhibits the release of proinflammatory cytokines, Inflammasome inhibitor Inhibits platelet aggregation.
Schlagworte: | (E)-3-(4-Methylphenylsulfonyl)-2-propenenenitrile |
Anwendung: | NFkappaB inhibitor |
CAS | 19542-67-7 |
MW: | 207,3 D |
ab 77,00 €
Artikelnummer: 100-4167C
Protein function: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the...
Schlagworte: | Anti-IKBA, Anti-NFKBIA, Anti-IkB-alpha, Anti-IkappaBalpha, Anti-I-kappa-B-alpha, Anti-NF-kappa-B inhibitor alpha,... |
Anwendung: | ELISA, IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
684,00 €
Artikelnummer: CDX-M0514-M005
Tetra-O-methylscutellarein is a bioactive component of Siam weed extract. It exhibits anti-inflammatory activity through inhibition of the NF-kappaB pathway. It suppressed IkappaB kinase complex alpha/beta (IKKalpha/beta) and Inhibitory-kappa-B-alpha (IkappaBalpha), inhibiting p65 translocation and thereby...
Schlagworte: | Scutellarein tetramethyl ether, 5-Methoxysalvigenin, 4',5,6,7-Tetramethoxyflavone, NSC53908 |
Anwendung: | Antiinflammatory agent |
CAS | 1168-42-9 |
MW: | 342.3 D |
ab 183,00 €
Artikelnummer: Cay15373-1
Transcriptional activation by NF-kappaB is limited by IkappaBalpha binding, which masks the NF-kappaB nuclear localization signal that initiates nuclear translocation. Cytokines trigger a signaling cascade of kinases that target IkappaBalpha for degradation, enabling NF-kappaB to promote gene expression. Because...
Schlagworte: | 6-(phenylsulfinyl)-tetrazolo[1,5-b]pyridazine |
Anwendung: | IkappaBalpha ubiquitination inhibitor |
CAS | 62645-28-7 |
MW: | 245.3 D |
ab 66,00 €
-15 %
Rabattaktion
Artikelnummer: ABE-10-6010-100
Protein function: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the...
Schlagworte: | Anti-IKBA, Anti-NFKBIA, Anti-IkB-alpha, Anti-IkappaBalpha, Anti-I-kappa-B-alpha, Anti-NF-kappa-B inhibitor alpha,... |
Anwendung: | FC |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
149,00 €
ab 126,65 €
Artikelnummer: ARG51651.100
Protein function: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the...
Schlagworte: | Anti-phospho-IKBA, Anti-phospho-NFKBIA, Anti-phospho-IkB-alpha, Anti-phospho-IkappaBalpha, Anti-phospho-I-kappa-B-alpha,... |
Anwendung: | ICC, IF, IHC (paraffin), WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 436,00 €