Zu "K04718" wurden 110 Artikel gefunden!
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NEU
Anti-SPHK2
Artikelnummer: CSB-PA040027.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-SK2, Anti-SK 2, Anti-SPK 2, Anti-Sphingosine kinase 2, SK 2 antibody, Sphingosine kinase 2 antibody, Sphingosine... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
NEU
Anti-SPHK2
Artikelnummer: CSB-PA548094.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SPHK2. Antigen Species: Human
| Schlagworte: | Anti-SK2, Anti-SK 2, Anti-SPK 2, Anti-Sphingosine kinase 2, SK 2 antibody, Sphingosine kinase 2 antibody, Sphingosine... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
NEU
Anti-SPHK2
Artikelnummer: CSB-PA565390.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SPHK2. Antigen Species: Human
| Schlagworte: | Anti-SK2, Anti-SK 2, Anti-SPK 2, Anti-Sphingosine kinase 2, SK 2 antibody, Sphingosine kinase 2 antibody, Sphingosine... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Opaganib
Artikelnummer: AG-CR1-3749-M025
Opaganib is a selective inhibitor of sphingosine kinase 2 (SPHK2, Ki = 9.8 µM), a lipid kinase that catalyzes formation of the lipid signaling molecule sphingosine 1-phosphate (S1P). S1P promotes cancer growth, and proliferation and pathological inflammation, including TNF-alpha signaling and other inflammatory...
| Schlagworte: | 3-(4-Chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide, ABC294640, Yeliva |
| Anwendung: | SPHK2 inhibitor |
| CAS | 915385-81-8 |
| MW: | 380.9 D |
ab 99,00 €
Defensamide
Artikelnummer: Cay37318-10
Defensamide is an activator of sphingosine kinase 1 (SPHK1). It increases sphingosine-1-phosphate (S1P) levels in primary human keratinocytes but does not affect S1P lyase activity in the same cells when used at a concentration of 100 µM. Defensamide (100 µM) increases protein levels of cathelicidin antimicrobial...
| Schlagworte: | (S)-methyl-2-hexanamido-3-(4-hydroxyphenyl)propanoate, N-(1-oxohexyl)-L-tyrosine, methyl ester |
| Anwendung: | SPHK1 activator |
| CAS | 1104874-94-3 |
| MW: | 293.4 D |
ab 109,00 €
Rat SPHK1 (Sphingosine Kinase 1) ELISA Kit
Artikelnummer: ELK-ELK0507.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat SPHK1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat SPHK1. Next,...
| Schlagworte: | SK 1, Sphk1, SPK 1, EC=2.3.1.-, Sphingosine kinase 1, Acetyltransferase SPHK1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Human SPHK1 (Sphingosine Kinase 1) ELISA Kit
Artikelnummer: ELK-ELK4112.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SPHK1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SPHK1. Next,...
| Schlagworte: | SK 1, SPK 1, EC=2.3.1.-, Sphingosine kinase 1, Acetyltransferase SPHK1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Sphingosine Kinase Inhibitor 2
Artikelnummer: Cay10009222-5
Sphingosine kinase isoforms, SPHK 1 and SPHK 2 , catalyze the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. Sphingosine kinase inhibitor 2 is an...
| Schlagworte: | SKI II, SPHK I2, 4-[[4-(4-chlorophenyl)-2-thiazolyl]amino]-phenol |
| Anwendung: | SPHK1 inhibitor |
| CAS | 312636-16-1 |
| MW: | 302.8 D |
ab 54,00 €
N,N-Dimethylsphingosine (d18:1)
Artikelnummer: Cay62575-5
N,N-Dimethylsphingosine is a metabolite of sphingosine and an inhibitor of sphingosine kinase (SPHK) with Ki values of 3.1, 6.8, and 2.3 µM in U937, PC12, and Swiss 3T3 cell extracts, respectively. It is selective for SPHK over PKC in PC12 cells when used at a concentration of 10 µM.Formal Name:...
| Schlagworte: | 2S-(dimethylamino)-4E-octadecene-1,3R-diol |
| Anwendung: | Sphingosine kinase inhibitor |
| CAS | 119567-63-4 |
| MW: | 327.6 D |
ab 74,00 €
PF-543 (hydrochloride)
Artikelnummer: Cay17034-25
PF-543 is a potent inhibitor of sphingosine kinase 1 (SPHK1, IC50 = 2 nM) that inhibits sphingosine-1-phosphate (S1P) binding to human recombinant SPHK1 (Ki = 3.6 nM). It is selective for SPHK1 over SPHK2 (IC50 = 356 nM) as well as a panel of protein and lipid kinases and S1P receptors at a concentration of 10 µM....
| Schlagworte: | 1-[[4-[[3-methyl-5-[(phenylsulfonyl)methyl]phenoxy]methyl]phenyl]methyl]-2R-pyrrolidinemethanol, monohydrochloride |
| Anwendung: | Sphingosine kinase 1 inhibitor |
| CAS | 1706522-79-3 |
| MW: | 502.1 D |
ab 43,00 €
CAY10621
Artikelnummer: Cay13371-1
CAY10621 is an inhibitor of sphingosine kinase 1 (SPHK1, IC50 = 3.3 µM). It is selective for SPHK1 over SPHK2 at 10 µM and PKC at concentrations less than 100 µM. CAY10621 inhibits SPHK1 activity by 70% in U937 cells when used at a concentration of 5 µM.Formal Name:...
| Schlagworte: | SKI 5C, SPHK1 Inhibitor 5C, (4S)-2,2-dimethyl-4-(1-oxo-2-hexadecyn-1-yl)-3-oxazolidinecarboxylic acid, 1,1-dimethylethyl... |
| Anwendung: | SPHK 1 inhibitor |
| CAS | 120005-55-2 |
| MW: | 435.6 D |
ab 38,00 €
Sphingosine Kinase 1 (human, recombinant)
Artikelnummer: Cay10348-25
Sphingosine kinase (SPHK) is an important enzyme in the sphingolipid metabolic pathway. SPHKs phosphorylate D-erythro-sphingosine to yield sphingosine-1-phosphate (S1P). To date two isoforms of SPHK, SPHK1 and SPHK2, have been identified & characterized from mammalian cells. Among them, SPHK1 has been implicated to...
| Schlagworte: | SK 1, SK 1, SPK 1, SPK 1, Sphingosine kinase 1, Sphingosine kinase 1, Acetyltransferase SPHK1, Acetyltransferase SPHK1 |
| Anwendung: | Enzyme activity |
| MW: | 47,5 kD |
571,00 €