Zu "K04710" wurden 19 Artikel gefunden!
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Fumonisin B1
Artikelnummer: Cay62580-5
Fumonisin B1 (FB1) is a mycotoxin that has been found in F. moniliforme. It inhibits ceramide synthase (IC50 = 0.1 µM for the rat liver enzyme). FB1 induces DNA fragmentation and apoptosis in CV-1 cells when used at concentrations of 5 and 25 µM, respectively. It is cytotoxic to primary rat hepatocytes and induces...
| Schlagworte: | FB1, (2R,2'R)-1,2,3-propanetricarboxylic acid,... |
| Anwendung: | Ceramide synthase inhibitor |
| CAS | 116355-83-0 |
| MW: | 721.8 D |
ab 98,00 €
Anti-CERS1
Artikelnummer: CSB-PA877434.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CERS1. Antigen Species: Human
| Schlagworte: | Anti-CerS1, Anti-Protein UOG-1, Anti-Ceramide synthase 1, Anti-LAG1 longevity assurance homolog 1, Anti-Longevity... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
C10 Ceramide (d18:1/10:0)
Artikelnummer: Cay22529-5
C10 ceramide is an endogenous, bioactive sphingolipid produced by ceramide synthase. C10 ceramide inhibits growth of wild-type and MDR1 gene-transfected MDA435/LCC6 human breast cancer cells with IC50 values of 44.1 and 46 µM, respectively. It also inhibits the growth of J774 murine macrophages in a dose-dependent...
| Schlagworte: | C10 Ceramide, Cer(d18:1/10:0), Ceramide (d18:1/10:0), N-decanoyl-D-erythro-Sphingosine,... |
| Anwendung: | Endogenous bioactive sphingolipid |
| CAS | 111122-57-7 |
| MW: | 453.7 D |
ab 110,00 €
C14 Ceramide (d18:1/14:0)
Artikelnummer: Cay22531-1
C14 Ceramide is an endogenous ceramide generated by ceramide synthase 6. During nutrient-deprivation-induced necroptosis in MEF cells, C14 ceramide levels increase in a time-dependent manner. C14 ceramide plasma levels were reduced in obese patients with or without diabetes following a 12-week supervised exercise...
| Schlagworte: | C14 Ceramide, Cer(d18:1/14:0), Ceramide (d18:1/14:0),... |
| Anwendung: | Endogenous ceramide |
| CAS | 34227-72-0 |
| MW: | 509.9 D |
ab 20,00 €
740 Y-P (trifluoroacetate salt)
Artikelnummer: Cay22598-1
740 Y-P is a synthetic phosphopeptide activator of PI3K. It contains amino acids from the Antennapedia protein, which acts as a cellular internalization sequence, followed by a sequence from PDGFR that is recognized by the SH2 domain of PI3K. 740 Y-P (15 µM) increases phosphorylation of PI3K, mammalian target of...
| Schlagworte: | L-arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-... |
| Anwendung: | Endogenous bioactive sphingolipid |
| CAS | 1236188-16-1 |
| MW: | 3270.7 D |
ab 163,00 €
C16 Ceramide-d7 (d18:1-d7/16:0)
Artikelnummer: Cay22787-1
C16 Ceramide-d7 is intended for use as an internal standard for the quantification of C16 ceramide (d18:1/16:0) by GC- or LC-MS. C16 Ceramide is a sphingolipid. It incorporates into the mitochondrial outer membrane and forms channels that increase its permeability. C16 Ceramide levels are increased by PPMP or MAPP...
| Schlagworte: | Ceramide-d7 (d18:1-d7/16:0), Cer-d7 (d18:1-d7/16:0), N-Palmitoyl-D-erythro-Sphingosine-d7, Palmitoyl Ceramide-d7,... |
| Anwendung: | GC-MS, LC-MS, Internal standard |
| CAS | 1840942-13-3 |
| MW: | 545 D |
ab 488,00 €
Anti-LASS1, Internal
Artikelnummer: ARG64713.100
Protein function: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner. [The UniProt Consortium]
| Schlagworte: | Anti-LAG1, Anti-CERS1, Anti-CerS1, Anti-Protein UOG-1, Anti-Ceramide synthase 1, Anti-LAG1 longevity assurance homolog 1,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
784,00 €
Anti-LASS1
Artikelnummer: NSJ-R34378-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: LAG1, CerS1 antibody, Ceramide synthase 1 Protein function: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the...
| Schlagworte: | Anti-LAG1, Anti-CERS1, Anti-CerS1, Anti-Protein UOG-1, Anti-Ceramide synthase 1, Anti-LAG1 longevity assurance homolog 1,... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
755,00 €
Fumonisin B1
Artikelnummer: LKT-F8149.1
A mycotoxin isolated from Fusarium moniliforme. This compound induces apoptosis in rat and monkey kidney cells.
| Anwendung: | Apoptosis inducer |
| CAS | 116355-83-0 |
| MW: | 721,83 D |
ab 415,00 €
Fumonisin B1
Artikelnummer: F9575-02.1
Fumonisin is a group of toxins (B1 or FB1, B2 or FB2, which are equally toxic, and B3 or FB3, which is relatively nontoxic) which are produced by fungi (Fusarium moniliforme and F. proliferatum) that causes equine leukoencephalomalacia, a disease of the central nervous system of equines and is associated with the...
| CAS | 116355-83-0 |
ab 393,00 €
Fumonisin B2
Artikelnummer: LKT-F8150.1
A Mycotoxin isolated from Fusarium moniliforme. This compound is an inhibitor of the enzyme spingosine acyltransferase.
| Schlagworte: | FB2 |
| Anwendung: | Sphingosine acyltransferase inhibitor |
| CAS | 116355-84-1 |
| MW: | 705,8 D |
ab 887,00 €
Anti-CERS1
Artikelnummer: G-PACO19924.50
CERS1 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human, Mouse and for use in ELISA, WB, IHC applications. CERS1 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Ceramide synthase that catalyzes formation of ceramide from sphinganine and...
| Schlagworte: | Anti-CerS1, Anti-Protein UOG-1, Anti-Ceramide synthase 1, Anti-LAG1 longevity assurance homolog 1, Anti-Longevity... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
363,00 €