Zu "K04710" wurden 26 Artikel gefunden!
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Fumonisin B1
Artikelnummer: Cay62580-5
Fumonisin B1 (FB1) is a mycotoxin that has been found in F. moniliforme. It inhibits ceramide synthase (IC50 = 0.1 µM for the rat liver enzyme). FB1 induces DNA fragmentation and apoptosis in CV-1 cells when used at concentrations of 5 and 25 µM, respectively. It is cytotoxic to primary rat hepatocytes and induces...
| Schlagworte: | FB1, (2R,2'R)-1,2,3-propanetricarboxylic acid,... |
| Anwendung: | Ceramide synthase inhibitor |
| CAS | 116355-83-0 |
| MW: | 721.8 D |
ab 98,00 €
Fumonisin B1
Artikelnummer: TGM-T15356-1mg
Description: Fumonisin B1 (Fumonisin-B1) is a mycotoxin produced by Fusarium oxysporum that is widely present in crops, contaminating them and posing a significant food safety hazard.Fumonisin B1 is structurally a sphingosine and sphingomyelin analog, and inhibits the biosynthesis of complex sphingolipids through...
| Schlagworte: | Fumonisin-B1 |
| Anwendung: | Ceramide synthase inhibitor |
| CAS | 116355-83-0 |
| MW: | 721.83 D |
291,00 €
Fumonisin B2
Artikelnummer: TGM-T15357-10mg
Description: Fumonisin B2 is a mycotoxin produced by Fusarium moniliforme in various grains. It also is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase). Which disrupts de novo sphingolipid biosynthesis. Target: Others. Smiles:...
| Anwendung: | Sphingosine acyltransferase inhibitor |
| CAS | 116355-84-1 |
| MW: | 705.83 D |
ab 420,00 €
C14 Ceramide (d18:1/14:0)
Artikelnummer: TGM-T35803-100mg
Description: C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's research. Smiles: CCCCCCCCCC CCC\C=C\[C@@H](O)[C@H](CO)NC(=O)CCCCCCCCCCCCC. References: Choi S,et al. Myristate-induced endoplasmic reticulum stress requires ceramide synthases 5/6...
| Schlagworte: | N-Myristoyl-D-sphingosine, Cer(d18:1/14:0) |
| Anwendung: | Endogenous ceramide |
| CAS | 34227-72-0 |
| MW: | 509.85 D |
ab 31,00 €
C16 Ceramide-d7
Artikelnummer: TGM-TMIH-0131-1mg
Description: C16 Ceramide-d7 is a deuterated compound of C16 Ceramide. Smiles: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])CCCCCCCCCC\C=C\[C@@H](O)[C@H](CO)NC(=O)CCCCCCCCCC CCCCC
| Anwendung: | GC-MS, LC-MS, internal standard |
| CAS | 1840942-13-3 |
| MW: | 544.94 D |
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740 Y-P
Artikelnummer: TGM-TQ0003-10mg
Description: 740 Y-P (740YPDGFR) is a potent and cell-permeable activator of PI3K. Target: Autophagy, PI3K. Smiles:...
| Schlagworte: | 740YPDGFR, PDGFR 740Y-P |
| Anwendung: | Endogenous bioactive sphingolipid |
| CAS | 1236188-16-1 |
| MW: | 3270.7 D |
ab 87,00 €
P053
Artikelnummer: TGM-T12342-10mg
Description: P053 is a potent, non-competitive, and selective ceramide synthase 1 (CerS1) inhibitor with an IC50 of 0.5 µM. It acts as an endogenous inhibitor of mitochondrial fatty acid oxidation in muscle and regulates whole-body adiposity[1]. Target: Others. Smiles: C[C@@](N)(CO)CCc1ccc(OCc2ccc(Cl)c(Cl)c2)cc1....
| Anwendung: | CerS1 inhibitor |
| CAS | 2748196-63-4 |
| MW: | 354.27 D |
ab 247,00 €
Anti-CERS1
Artikelnummer: CSB-PA877434.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CERS1. Antigen Species: Human
| Schlagworte: | Anti-CerS1, Anti-Protein UOG-1, Anti-Ceramide synthase 1, Anti-LAG1 longevity assurance homolog 1, Anti-Longevity... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
740 Y-P (trifluoroacetate salt)
Artikelnummer: Cay22598-1
740 Y-P is a synthetic phosphopeptide activator of PI3K. It contains amino acids from the Antennapedia protein, which acts as a cellular internalization sequence, followed by a sequence from PDGFR that is recognized by the SH2 domain of PI3K. 740 Y-P (15 µM) increases phosphorylation of PI3K, mammalian target of...
| Schlagworte: | L-arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-... |
| Anwendung: | Endogenous bioactive sphingolipid |
| CAS | 1236188-16-1 |
| MW: | 3270.7 D |
ab 163,00 €
C10 Ceramide (d18:1/10:0)
Artikelnummer: Cay22529-5
C10 ceramide is an endogenous, bioactive sphingolipid produced by ceramide synthase. C10 ceramide inhibits growth of wild-type and MDR1 gene-transfected MDA435/LCC6 human breast cancer cells with IC50 values of 44.1 and 46 µM, respectively. It also inhibits the growth of J774 murine macrophages in a dose-dependent...
| Schlagworte: | C10 Ceramide, Cer(d18:1/10:0), Ceramide (d18:1/10:0), N-decanoyl-D-erythro-Sphingosine,... |
| Anwendung: | Endogenous bioactive sphingolipid |
| CAS | 111122-57-7 |
| MW: | 453.7 D |
ab 110,00 €
C14 Ceramide (d18:1/14:0)
Artikelnummer: Cay22531-1
C14 Ceramide is an endogenous ceramide generated by ceramide synthase 6. During nutrient-deprivation-induced necroptosis in MEF cells, C14 ceramide levels increase in a time-dependent manner. C14 ceramide plasma levels were reduced in obese patients with or without diabetes following a 12-week supervised exercise...
| Schlagworte: | C14 Ceramide, Cer(d18:1/14:0), Ceramide (d18:1/14:0),... |
| Anwendung: | Endogenous ceramide |
| CAS | 34227-72-0 |
| MW: | 509.9 D |
ab 20,00 €
C16 Ceramide-d7 (d18:1-d7/16:0)
Artikelnummer: Cay22787-1
C16 Ceramide-d7 is intended for use as an internal standard for the quantification of C16 ceramide (d18:1/16:0) by GC- or LC-MS. C16 Ceramide is a sphingolipid. It incorporates into the mitochondrial outer membrane and forms channels that increase its permeability. C16 Ceramide levels are increased by PPMP or MAPP...
| Schlagworte: | Ceramide-d7 (d18:1-d7/16:0), Cer-d7 (d18:1-d7/16:0), N-Palmitoyl-D-erythro-Sphingosine-d7, Palmitoyl Ceramide-d7,... |
| Anwendung: | GC-MS, LC-MS, Internal standard |
| CAS | 1840942-13-3 |
| MW: | 545 D |
ab 488,00 €