Zu "K04692" wurden 197 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
STAT3 (human), recombinant protein
Artikelnummer: ABS-PP-466.20
| Schlagworte: | Signal transducer and activator of transcription 3, Acute-phase response factor, Recombinant Human STAT3 Protein |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 26 kD |
ab 90,00 €
Anti-STAT3 (phospho Y705)
Artikelnummer: ABS-KC-4287.100
Protein function: Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors (PubMed:10688651, PubMed:12359225, PubMed:12873986, PubMed:15194700, PubMed:17344214, PubMed:18242580, PubMed:23084476). Once activated, recruits coactivators,...
| Schlagworte: | Anti-Signal transducer and activator of transcription 3, Anti-Acute-phase response factor, STAT3 (phospho Y705) Antibody |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-STAT3
Artikelnummer: ABS-KC-6263.100
Protein function: Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors (PubMed:10688651, PubMed:12359225, PubMed:12873986, PubMed:15194700, PubMed:17344214, PubMed:18242580, PubMed:23084476). Once activated, recruits coactivators,...
| Schlagworte: | Anti-Signal transducer and activator of transcription 3, Anti-Acute-phase response factor, STAT3 Antibody |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, rat, mouse |
ab 232,00 €
STAT3, GST-tag
Artikelnummer: BPS-75003
Human signal transducer and activator of transcription 3 (STAT3), GenBank Accession No. NM_139276, full length with N-terminal GST-tag, MW=120 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
| Schlagworte: | Acute-phase response factor, Signal transducer and activator of transcription 3, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 120 kD |
774,00 €
STAT3 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-06624-100ug
Description: STAT3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 65.31 kDa and the accession number is P40763-1.
| Schlagworte: | signal transducer and activator of transcription 3 (acute-phase response factor), ADMIO, HIES, APRF |
| MW: | 65.31 kD |
ab 599,00 €
Cucurbitacin I
Artikelnummer: TGM-TQ0196-1mg
Description: Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity. Target: STAT, JAK. Smiles: [H][C@@]12CC=C3[C@@]([H])(C=C(O)C(=O)C3(C)C)[C@]1(C)C(=O)C[C@]1(C)[C@H]([C@H](O)C[C@@]21C)[C@@](C)(O)C(=O)\C=C\C(C)(C)O. References: Song J, et al. Cucurbitacin I...
| Schlagworte: | JSI-124, NSC-521777, Elatericin B |
| Anwendung: | STAT3/JAK signaling pathway inhibitor |
| CAS | 2222-07-3 |
| MW: | 514.65 D |
ab 77,00 €
SH5-07
Artikelnummer: TGM-TQ0052-100mg
Description: SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 µM). Target: STAT. Smiles: CN(CC(=O)N(Cc1ccc(cc1)C1CCCCC1)c1ccc(cc1)C(=O)NO)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F. References: Yue P,et al. Hydroxamic Acid and Benzoic Acid-Based STAT3 Inhibitors Suppress Human Glioma and Breast Cancer Phenotypes In...
| Anwendung: | STAT3 inhibitor |
| CAS | 1456632-41-9 |
| MW: | 625.61 D |
ab 31,00 €
Colivelin
Artikelnummer: TGM-TP1856-100mg
Description: Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN). Target: STAT, Beta Amyloid. Smiles:...
| Anwendung: | Potent synthetic peptide STAT3 activator |
| CAS | 867021-83-8 |
| MW: | 2645.1 D |
ab 236,00 €
SH-4-54
Artikelnummer: TGM-T6669-100mg
Description: SH-4-54 is a most potent, small molecule, nonphosphorylated STAT3 inhibitor. Target: STAT. Smiles: CN(CC(=O)N(Cc1ccc(cc1)C1CCCCC1)c1ccc(cc1)C(O)=O)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F. References: Haftchenary S, et al. ACS Med Chem Lett. 2013, 4(11), 1102-1107.
| Anwendung: | STAT3 inhibitor |
| CAS | 1456632-40-8 |
| MW: | 610.59 D |
ab 43,00 €
HO-3867
Artikelnummer: TGM-T6537-100mg
Description: HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor. Target: Apoptosis, STAT. Smiles: CC1(C)C=C(CN2C\C(=C/c3ccc(F)cc3)C(=O)\C(C2)=C\c2ccc(F)cc2)C(C)(C)N1O. References: Selvendiran K, et al. Mol Cancer Ther. 2010, 9(5), 1169-1179.
| Schlagworte: | HO3867 |
| Anwendung: | STAT3 inhibitor |
| CAS | 1172133-28-6 |
| MW: | 464.55 D |
ab 48,00 €
STAT3 Reporter Kit (STAT3 Signaling Pathway)
Artikelnummer: BPS-79730
The STAT3 Reporter kit is designed for monitoring the activity of the STAT3 signaling pathway in cultured cells. The kit contains transfection-ready STAT3 luciferase reporter vector. This reporter contains a firefly luciferase gene under the control of STAT3-responsive element located upstream of a minimal promoter....
| Schlagworte: | Acute-Phase Response Factor, APRF, ADMIO1, HIES, |
| Anwendung: | STAT3 pathway activity monitoring, activator / inhibitor screening |
| Spezies-Reaktivität: | human |
1.005,00 €
5,15-DPP
Artikelnummer: TGM-T21501-5mg
Description: 5,15-Diphenylporphyrin (5,15-DPP) is a selective STAT3-SH2 antagonist with IC50 values of 0.28 µM for STAT3 and 10 µM for STAT1 [1]. Target: Others. Smiles: c1cc2nc1cc1ccc([nH]1)c(-c1ccccc1)c1ccc(cc3ccc([nH]3)c2-c2ccccc2)n1
| Anwendung: | STAT3 dimerization inhibitor |
| CAS | 22112-89-6 |
| MW: | 462.54 D |
40,00 €