Zu "K04688" wurden 207 Artikel gefunden!
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Anti-RPS6KB1
Artikelnummer: ABS-KC-4260.100
Protein function: Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by...
| Schlagworte: | Anti-Ribosomal protein S6 kinase beta-1, Anti-S6K-beta-1, Anti-S6K1, Anti-70 kDa ribosomal protein S6 kinase 1,... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, rat, mouse |
ab 206,00 €
L-Norvaline
Artikelnummer: TGM-T4788-500mg
Description: L-Norvaline is an arginase inhibitor and a non-protein branched-chain amino acid. L-Norvaline has previously been reported as a natural component of the antifungal peptide of Bacillus subtilis. L-Norvaline and other modified branched-chain amino acids have received attention in recent studies because...
| Anwendung: | Arginase/p70S6K1 inhibitor, amino fatty acid |
| CAS | 6600-40-4 |
| MW: | 117.15 D |
42,00 €
Bisindolylmaleimide V
Artikelnummer: TGM-T7790-10mg
Description: Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor. Target: PKC, S6 Kinase. Smiles: CN1C(=O)C(C2=CNC3=CC=CC=C23)=C(C1=O)C1=CNC2=CC=CC=C12. References: Marmy-Conus N , Hannan K M , Pearson R B . Ro 31-6045, the inactive analogue of the protein kinase C...
| Anwendung: | S6K inhibitor |
| CAS | 113963-68-1 |
| MW: | 341.36 D |
ab 67,00 €
S6K1/RPS6KB1 Protein, Human, Recombinant (GST)
Artikelnummer: TGM-TMPY-04540-50ug
Description: PS6K, also known as RPS6KB1, is a serine/threonine-protein kinase. It belongs to the RSK (ribosomal s6 kinase) family. Members of this family function in signal transduction. PS6K is an isoform of p70 ribosomal S6 kinase (S6K). S6K can be activated by mitogenic stimuli such as growth factors, insulin...
| Schlagworte: | p70(S6K)-alpha, p70-alpha, p70-alpha, p70(S6K)-alpha, PS6K, ribosomal protein S6 kinase, polypeptide 1, S6K-beta-1,... |
| MW: | 85.4 kD |
397,00 €
LY-2584702 tosylate salt
Artikelnummer: TGM-T1746-100mg
Description: LY-2584702 tosylate salt, a selective ATP-competitive p70S6K inhibitor, is being used in clinical trials for cancer treatment. Target: S6 Kinase. Smiles: Cc1ccc(cc1)S(O)(=O)=O.Cn1cc(nc1C1CCN(CC1)c1ncnc2[nH]ncc12)-c1ccc(F)c(c1)C(F)(F)F. References: Tolcher A, et al. Eur J Cancer. 2014, 50(5), 867-875.
| Schlagworte: | LY2584702 tosylate |
| Anwendung: | p70S6K signaling inhibitor |
| CAS | 1082949-68-5 |
| MW: | 617.62 D |
ab 31,00 €
M2698
Artikelnummer: TGM-T11928-100mg
Description: M2698 (MSC2363318A) is an inhibitor of p70S6K, Akt1 and Akt3 with IC50s of 1 nM. M2698 shows anti-cancer activity. Target: mTOR, Akt. Smiles: N([C@H](CN1CCC1)C2=CC(C(F)(F)F)=C(Cl)C=C2)C=3C4=C(C(C(N)=O)=CC=C4)N=CN3. References: Machl A, et al. M2698 is a potent dual-inhibitor of p70S6K and Akt that...
| Schlagworte: | MSC2363318A |
| Anwendung: | P70S6K / Akt1 dual inhibitor |
| CAS | 1379545-95-5 |
| MW: | 449.86 D |
ab 43,00 €
Ribosomal protein S6 kinase beta-2 (RPS6KB2), partial,...
Artikelnummer: CSB-RP029054h.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-210aa. Protein Length: Partial. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MAAVFDLDLE TEEGSEGEGE PELSPADACP LAELRAAGLE PVGHYEEVEL TETSVNVGPE RIGPHCFELL RVLGKGGYGK VFQVRKVQGT NLGKIYAMKV LRKAKIVRNA KDTAHTRAER NILESVKHPF IVELAYAFQT...
| Schlagworte: | SRK, S6K2, STK14B, P70S6K2, RPS6KB2, S6K-beta, p70 S6KB, p70-beta, p70-S6K 2, S6K-beta-2, EC=2.7.11.1, p70 S6K-beta, p70... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 50.2 kD |
ab 219,00 €
Anti-RPS6KB1
Artikelnummer: CSB-PA003686.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-S6K1, Anti-STK14A, Anti-P70S6K1, Anti-RPS6KB1, Anti-p70 S6KA, Anti-p70-S6K 1, Anti-S6K-beta-1, Anti-p70 S6K-alpha,... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-RPS6KB1
Artikelnummer: CSB-PA003688.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-S6K1, Anti-STK14A, Anti-P70S6K1, Anti-RPS6KB1, Anti-p70 S6KA, Anti-p70-S6K 1, Anti-S6K-beta-1, Anti-p70 S6K-alpha,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-RPS6KB2
Artikelnummer: CSB-PA003695.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-SRK, Anti-S6K2, Anti-STK14B, Anti-P70S6K2, Anti-RPS6KB2, Anti-p70 S6KB, Anti-S6K-beta, Anti-p70-beta, Anti-p70-S6K 2,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
126,00 €
Anti-RPS6KB2
Artikelnummer: CSB-PA018470.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: RPS6KB2. Antigen Species: Human
| Schlagworte: | Anti-SRK, Anti-S6K2, Anti-STK14B, Anti-P70S6K2, Anti-RPS6KB2, Anti-p70 S6KB, Anti-S6K-beta, Anti-p70-beta, Anti-p70-S6K 2,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Anti-Phospho-RPS6KB1 (S447)
Artikelnummer: CSB-PA000604.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-S6K1, Anti-phospho-STK14A, Anti-phospho-P70S6K1, Anti-phospho-RPS6KB1, Anti-phospho-p70 S6KA,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €