Zu "K04675" wurden 78 Artikel gefunden!
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LDN-193189 2HCl
Artikelnummer: TGM-T35348-100mg
Description: LDN-193189 2HCl (DM-3189 2HCl) is a selective BMP signaling inhibitor that inhibits ALK1,ALK2,ALK3 and ALK6, showing IC50s of 0.8 nM, 0.8 nM, 5.3 nM, and 16.7 nM, respectively, in kinase assays.LDN-193189 2HCl inhibited the transcriptional activity of BMP type I receptors in C2C12 cells, with IC50s of 5...
| Schlagworte: | DM-3189 2HCl, LDN-193189 2HCl |
| Anwendung: | ALK1 / ALK2 / ALK3 / ALK6 inhibitor |
| CAS | 1435934-00-1 |
| MW: | 479.4 D |
ab 67,00 €
INCB-000928
Artikelnummer: TGM-T77726-10mg
Description: Zilurgisertib (INCB-000928) is a selective and potent ALK 2 inhibitor for the study of cancer and MF anemia. Target: ALK. Smiles: [H][C@]12C[C@]1(CN(C2)C1CCOCC1)c1ccc(cc1)-c1cnc(N)c(c1)C(=O)NC12CCC(O)(CC1)CC2. References: Li J, et al. Preparation of aminopyridine derivatives and their use as selective...
| Anwendung: | Targets activin receptor type-1 [EC:2.7.11.30] (ACVR1, ALK2) |
| CAS | 2173389-57-4 |
| MW: | 502.65 D |
ab 227,00 €
Blu-782
Artikelnummer: TGM-T8108-100mg
Description: Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM). Target: ALK. Smiles: CCOC1(CCN(CC1)C(C)C)c1ccc(nc1)-c1cc2c(ccnn2c1)N1CCN(CC1)C(=O)O[C@@H]1CCOC1. References: ALK2-IN-1
| Schlagworte: | ALK2-IN-1 |
| Anwendung: | Targets activin receptor type-1 [EC:2.7.11.30] (ACVR1, ALK2) |
| CAS | 2141955-96-4 |
| MW: | 562.7 D |
ab 74,00 €
ALK-2/ACVR1 Protein, Mouse, Recombinant (His & hFc)
Artikelnummer: TGM-TMPY-01096-200ug
Description: ALK-2/ACVR1 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 40 kDa and the accession number is P37172.
| Schlagworte: | Acvrlk2, ActRIA, Tsk7L, activin A receptor, type I, Alk-2, ActR-I, ALK2, D330013D15Rik, SKR1, Acvr, Alk8 |
| MW: | 40 kD |
922,00 €
ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc)
Artikelnummer: TGM-TMPY-00658-200ug
Description: ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is D3DPA4.
| Schlagworte: | activin A receptor, type I, ACTRI, SKR1, TSRI, FOP, ACVR1A, ACVRLK2, ALK2 |
| MW: | 39.6 kD |
922,00 €
ALK-2/ACVR1 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-04774-100ug
Description: ALK-2/ACVR1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 12.8kDa and the accession number is Q04771.
| Schlagworte: | ACVRLK2, FOP, activin A receptor, type I, ACTRI, TSRI, ALK2, ACVR1A, SKR1 |
| MW: | 12.8 kD |
ab 386,00 €
ALK-2/ACVR1 Protein, Rat, Recombinant (hFc)
Artikelnummer: TGM-TMPY-03157-200ug
Description: ALK-2/ACVR1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.5 kDa and the accession number is P80201.
| Schlagworte: | activin A receptor, type I |
| MW: | 38.5 kD |
922,00 €
ALK-2/ACVR1 Protein, Cynomolgus, Recombinant (hFc)
Artikelnummer: TGM-TMPY-03247-200ug
Description: ALK-2/ACVR1 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.2 kDa and the accession number is F7A9J8.
| Schlagworte: | activin A receptor, type I |
| MW: | 38.2 kD |
922,00 €
ALK-2/ACVR1 Protein, Canine, Recombinant (hFc)
Artikelnummer: TGM-TMPY-03706-200ug
Description: ALK-2/ACVR1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.6 kDa and the accession number is A0A8C0MPL7.
| Schlagworte: | activin A receptor, type I |
| MW: | 38.6 kD |
922,00 €
ALK-2/ACVR1 Protein, Canine, Recombinant (His)
Artikelnummer: TGM-TMPY-03707-200ug
Description: ALK-2/ACVR1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13 kDa and the accession number is A0A8C0MPL7.
| Schlagworte: | activin A receptor, type I |
| MW: | 13 kD |
922,00 €
LDN-212854
Artikelnummer: TGM-T1900-100mg
Description: LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-beta type I receptors, possesses differences towards ALK2(IC50=1.3 nM) versus ALK1/3 compared to other inhibitors. Target: ALK, TGF-beta/Smad. Smiles:...
| Schlagworte: | BMP Inhibitor III, LDN212854 |
| Anwendung: | ALK2 inhibitor |
| CAS | 1432597-26-6 |
| MW: | 406.48 D |
ab 42,00 €
DMH-1
Artikelnummer: TGM-T1942-100mg
Description: DMH-1 is a potent and selective Bone Morphogenetic Protein (BMP) inhibitor. Target: ALK, Autophagy, TGF-beta/Smad. Smiles: CC(C)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12. References: Hao J, et al. ACS Chem Biol. 2010, 5(2), 245-253.
| Schlagworte: | DMH1 |
| Anwendung: | ALK2 inhibitor |
| CAS | 1206711-16-1 |
| MW: | 380.44 D |
ab 53,00 €