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Zu "K04634" wurden 23 Artikel gefunden!
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Artikelnummer: TGM-T27387-1mg
Description: FR900359, a non-ribosomal cyclic peptide derived from the soil bacterium Chromobacterium oxysporum, is a macrocyclic Gq protein inhibitor that inhibits melanoma cell proliferation and can be used in studies of asthma, inflammation, and cancer. Target: Apoptosis, ERK. Smiles:...
Schlagworte: | FR 900359, FR-900359 |
Anwendung: | Cyclic depsipeptide, Galphaq, Galpha11, Galpha14 inhibitor |
CAS | 107530-18-7 |
MW: | 1002.16 D |
654,00 €
Artikelnummer: TGM-TMPH-02696-100ug
Description: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in...
Schlagworte: | Guanine nucleotide-binding protein alpha-q, Gnaq, Guanine nucleotide-binding protein G(q) subunit alpha |
MW: | 49.2 kD |
ab 352,00 €
Artikelnummer: TGM-T17273-1mg
Description: YM-254890, a macrocyclohexapeptide isolated from Chromobacterium sp, is a selective and potent inhibitor of Galphaq/11 protein, inhibits ADP-induced platelet aggregation and inhibits G protein signaling. Target: P2Y Receptor. Smiles:...
Schlagworte: | YM254890, YM 254890 |
Anwendung: | G alpha q family inhibitor |
CAS | 568580-02-9 |
MW: | 960.08 D |
1.176,00 €
Artikelnummer: AG-CN2-0509-MC05
Off-white solid. Soluble in DMSO (10mg/ml). Cyclic depsipeptide composed of unique amino acids differing from normal amino acids, Membrane permeable, potent and selective Galphaq family inhibitor, Inhibits the signal transduction of Galphaq, Galpha11 and Galpha14 (IC50=0.095&mu,M) by blocking the exchange of GDP for...
Schlagworte: | QS 3666A |
Anwendung: | G alpha q family inhibitor |
CAS | 568580-02-9 |
MW: | 960,1 D |
ab 220,00 €
Artikelnummer: CSB-BP707843MOa0.1
Organism: Mus musculus (Mouse). Source: Baculovirus. Expression Region: 1-559aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MRRLSSWRKM ATAEKQKHDG RVKIGHYILG DTLGVGTFGK VKVGKHELTG HKVAVKILNR QKIRSLDVVG KIRREIQNLK LFRHPHIIKL YQVISTPSDI FMVMEYVSGG ELFDYICKNG RLDEKESRRL...
Schlagworte: | Prkaa1, ACACA kinase, EC=2.7.11.26, HMGCR kinase, AMPK subunit alpha-1, Tau-protein kinase PRKAA1, Acetyl-CoA carboxylase... |
Anwendung: | Activity not tested |
Exprimiert in: | Insect cells |
Ursprungsart: | mouse |
MW: | 65 kD |
ab 474,00 €
Artikelnummer: CSB-EP009594MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-359aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MTLESIMACC LSEEAKEARR INDEIERQLR RDKRDARREL KLLLLGTGES GKSTFIKQMR IIHGSGYSDE DKRGFTKLVY QNIFTAMQAM IRAMDTLKIP YKYEHNKAHA...
Schlagworte: | Gnaq, Guanine nucleotide-binding protein alpha-q, Guanine nucleotide-binding protein G(q) subunit alpha, Recombinant Mouse... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | mouse |
MW: | 49.2 kD |
ab 354,00 €
Artikelnummer: CSB-EP342271HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-359aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MTLESIMACC LSEEAKEARR INDEIERQLR RDKRDARREL KLLLLGTGES GKSTFIKQMR IIHGSGYSDE DKRGFTKLVY QNIFTAMQAM IRAMDTLKIP YKYEHNKAHA QLVREVDVEK VSAFENPYVD...
Schlagworte: | GAQ, GNAQ, Guanine nucleotide-binding protein alpha-q, Guanine nucleotide-binding protein G(q) subunit alpha, Recombinant... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 48.1 kD |
ab 283,00 €
Artikelnummer: Cay33666-250
FR900359 is a cyclic depsipeptide that has been found in A. crenata and is an inhibitor of Galphaq, Galpha11, and Galpha14 (IC50s = 13.18, 10.47, and 10 nM, respectively). It is selective for these Galpha subunits over a panel of additional Galpha subunits, including Galphas and Galphai, in bioluminescence resonance...
Schlagworte: | UBO-QIC,... |
Anwendung: | Cyclic depsipeptide, Galphaq, Galpha11, Galpha14 inhibitor |
CAS | 107530-18-7 |
MW: | 1002.2 D |
ab 158,00 €
Artikelnummer: Cay29735-1
YM-254890 is cyclic depsipeptide originally isolated from Chromobacterium and an inhibitor of Galphaq/11. It inhibits Galphaq/11-mediated intracellular calcium mobilization induced by 2MeSADP or methacholine in C6-15 cells expressing the purinergic P2Y1 receptor (IC50 = 0.15 µM) and in CHO cells expressing M1...
Schlagworte: | N-acetyl-L-threonyl-(alphaR)-alpha-hydroxybenzenepropanoyl-2,3-didehydro-N-methylalanyl-L-alanyl-N-methyl-L-alanyl-(3R)-3-... |
Anwendung: | Cyclic depsipeptide Galphaq/11 inhibitor |
CAS | 568580-02-9 |
MW: | 960.1 D |
423,00 €
-30 %
Rabattaktion
Artikelnummer: ARG10606.50
Protein function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells...
Schlagworte: | Anti-GAQ, Anti-GNAQ, Anti-Guanine nucleotide-binding protein alpha-q, Anti-Guanine nucleotide-binding protein G(q) subunit... |
Anwendung: | IHC (paraffin), WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
528,00 €
369,60 €
Artikelnummer: NSJ-R32120
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Guanine nucleotide-binding protein G(q) subunit alpha is a protein that in humans is encoded by the GNAQ gene. Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular...
Schlagworte: | Anti-GAQ, Anti-GNAQ, Anti-Guanine nucleotide-binding protein alpha-q, Anti-Guanine nucleotide-binding protein G(q) subunit... |
Anwendung: | WB, IHC (paraffin) |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Artikelnummer: NSJ-R34779-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: ALPHA-q, Guanine nucleotide binding protein, G-ALPHA-q, GAQ Protein function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane...
Schlagworte: | Anti-GAQ, Anti-GNAQ, Anti-Guanine nucleotide-binding protein alpha-q, Anti-Guanine nucleotide-binding protein G(q) subunit... |
Anwendung: | WB, ELISA (peptide) |
Wirt: | Goat |
Spezies-Reaktivität: | human, mouse, rat, swine |
755,00 €