Zu "K04603" wurden 58 Artikel gefunden!
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GRM1 (human), recombinant protein
Artikelnummer: ABS-PP-427.20
| Schlagworte: | Metabotropic glutamate receptor 1, mGluR1, Recombinant Human GRM1 Protein |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 10.5 kD |
ab 90,00 €
VU0483605
Artikelnummer: TGM-T21747-1mg
Description: VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively. Target: GluR. Smiles: Clc1cccc2C(=O)N(C(=O)c12)c1ccc(NC(=O)c2ncccc2Cl)cc1Cl. References: Cho HP, Garcia-Barrantes PM, Brogan JT, et al. Chemical modulation of...
| Anwendung: | Selective positive mGluR1 allosteric modulator |
| CAS | 1623101-11-0 |
| MW: | 446.67 D |
ab 37,00 €
E4CPG
Artikelnummer: TGM-T3477-100mg
Description: E4CPG is a novel group I/II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG. Target: GluR. Smiles: CCC(N)(C(O)=O)c1ccc(cc1)C(O)=O. References: Sekiyama N et al. Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptorsubtypes....
| Anwendung: | mGluR1 / mGluR2 antagonist |
| CAS | 170846-89-6 |
| MW: | 223.23 D |
ab 31,00 €
Ro 67-7476
Artikelnummer: TGM-T3478-100mg
Description: Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 of 60.1 nM. Target: GluR. Smiles: Cc1ccc(cc1)S(=O)(=O)N1CCC[C@H]1c1ccc(F)cc1. References: Hemstapat K et al. A novel class of positive...
| Anwendung: | Positive allosteric mGlu1 receptor modulator |
| CAS | 298690-60-5 |
| MW: | 319.39 D |
ab 31,00 €
CFMTI
Artikelnummer: TGM-T3482-100mg
Description: CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM). The selectivity of CFMTI to mGluR1 is higher 2000-fold than mGluR5. Target: GluR. Smiles: Cc1c(nnn1-c1cccnc1F)-c1ccc2C(=O)N(Cc2c1)C1CC1. References: Satow A et al. Unique antipsychotic...
| Anwendung: | mGluR1 allosteric antagonist |
| CAS | 864864-17-5 |
| MW: | 349.36 D |
ab 55,00 €
trans-ACPD
Artikelnummer: TGM-T3484-100mg
Description: trans-ACPD ((±)-trans-ACPD) is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD. trans-ACPD is a selective agonist of the mGluR (metabotropic glutamate receptor), active at the group I/II mGlu receptors (EC50: 2/15/23/800 µM, mGluR2/1/5/4). Target: GluR. Smiles: NC1(CCC(C1)C(O)=O)C(O)=O....
| Schlagworte: | (±)-trans-ACPD, Trans-(±)-ACP, 1-amino-1,3-dicarboxycyclopentane |
| Anwendung: | mGluR agonist |
| CAS | 67684-64-4 |
| MW: | 173.17 D |
ab 42,00 €
(±)-LY367385
Artikelnummer: TGM-T39406-10mg
Description: (±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist. LY367385 exhibits a high inhibitory activity against quisqualate-induced phosphoinositide (PI) hydrolysis, with an IC50 value of 8.8 µM. In contrast, its inhibitory activity against mGlu5a is...
| Schlagworte: | (±)-LY367385 |
| Anwendung: | mGluR1alpha antagonist |
| CAS | 198419-90-8 |
| MW: | 209.201 D |
ab 154,00 €
JNJ16259685
Artikelnummer: TGM-T5512-100mg
Description: JNJ16259685 (TN.T 16259685) is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19 nM. Target: GluR. Smiles: CO[C@H]1CC[C@H](CC1)C(=O)c1ccc2nc3OCCCc3cc2c1. References: Hodgson RA, et al. Characterization of the selective...
| Schlagworte: | .TN.T 16259685 |
| Anwendung: | MGluR1a antagonist |
| CAS | 409345-29-5 |
| MW: | 325.4 D |
ab 42,00 €
FITM
Artikelnummer: TGM-T7292-100mg
Description: FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM). Target: GluR. Smiles: CC(C)Nc1cc(ncn1)-c1csc(n1)N(C)C(=O)c1ccc(F)cc1. References: Hayes M , Choudhary V , Ojha N , et al. Fat storage-inducing transmembrane (FIT or FITM) proteins are related to lipid...
| Anwendung: | mGluR1 antagonist |
| CAS | 932737-65-0 |
| MW: | 371.43 D |
ab 31,00 €
(S)-3,5-DHPG
Artikelnummer: Cay14411-1
(S)-3,5-DHPG, known more commonly as DHPG, is an agonist of the group I metabotropic glutamate receptors (mGluRs), binding both mGluR1a and mGluR5a (Ki = 0.9 and 3.9 µM, respectively) but not ionotropic glutamate receptors. The (S)-enantiomer is about ten times more potent than the (R)-enantiomer. (S)-3,5-DHPG is...
| Schlagworte: | (S)-3,5-Dihydroxyphenylglycine, (alphaS)-amino-3,5-dihydroxy-benzeneacetic acid |
| Anwendung: | mGluR1 / mGluR5a agonist |
| CAS | 162870-29-3 |
| MW: | 183.2 D |
ab 78,00 €
Anti-GRM1
Artikelnummer: CSB-PA054030.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GRM1. Antigen Species: Human
| Schlagworte: | Anti-GRM1, Anti-GPRC1A, Anti-mGluR1, Anti-Metabotropic glutamate receptor 1, Glutamate receptor metabotropic 1 antibody,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-GRM1
Artikelnummer: CSB-PA559950.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GRM1. Antigen Species: Human
| Schlagworte: | Anti-GRM1, Anti-GPRC1A, Anti-mGluR1, Anti-Metabotropic glutamate receptor 1, Glutamate receptor metabotropic 1 antibody,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €