Zu "K04583" wurden 39 Artikel gefunden!
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NEU
NNC-0640
Artikelnummer: Cay41234-1
NNC-0640 is a negative allosteric modulator of the glucagon receptor (GCGR, Ki = 39.8 nM).Formal Name: 4-[[(4-cyclohexylphenyl)[[[3-(methylsulfonyl)phenyl]amino]carbonyl]amino]methyl]-N-2H-tetrazol-5-yl-benzamide. CAS Number: 307986-98-7. Molecular Formula: C29H31N7O4S. Formula Weight: 573.7. Purity: >98%....
| Schlagworte: | 4-[[(4-cyclohexylphenyl)[[[3-(methylsulfonyl)phenyl]amino]carbonyl]amino]methyl]-N-2H-tetrazol-5-yl-benzamide |
| Anwendung: | GCGR negative allosteric modulator |
| CAS | 307986-98-7 |
| MW: | 573.7 D |
ab 34,00 €
NEU
Glucagon Receptor Antagonist 3
Artikelnummer: Cay41243-1
Glucagon receptor antagonist 3 is an antagonist of the glucagon receptor.Formal Name: (alphaR,4R)-rel-4-(4-fluoro-2-hydroxyphenyl)-alpha-methyl-2,6-bis(1-methylethyl)-5-propyl-3-pyridinemethanol. CAS Number: 202917-17-7. Molecular Formula: C22H30FNO2. Formula Weight: 359.5. Purity: >95%. Formulation: (Request...
| Schlagworte: | (alphaR,4R)-rel-4-(4-fluoro-2-hydroxyphenyl)-alpha-methyl-2,6-bis(1-methylethyl)-5-propyl-3-pyridinemethanol |
| Anwendung: | Glucagon receptor antagonist |
| CAS | 202917-17-7 |
| MW: | 359.5 D |
ab 127,00 €
Glucagon receptor (GCGR), partial, human, recombinant
Artikelnummer: CSB-BP009316HU1.1
Organism: Homo sapiens (Human). Source: Baculovirus. Expression Region: 26-136aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: AQVMDFLFEK WKLYGDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPANT TANISCPWYL PWHHKVQHRF VFKRCGPDGQ WVRGPRGQPW RDASQCQMDG EEIEVQKEVA K....
| Schlagworte: | GCGR, GL-R, Glucagon receptor, Recombinant Human Glucagon receptor (GCGR), partial |
| Anwendung: | Activity not tested |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 16.9 kD |
ab 474,00 €
Glucagon receptor (GCGR), human, recombinant
Artikelnummer: CSB-CF009316HU.100
Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 26-477aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: AQVMDFLFEK WKLYGDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPANT TANISCPWYL PWHHKVQHRF VFKRCGPDGQ WVRGPRGQPW...
| Schlagworte: | GCGR, GL-R, Glucagon receptor, Recombinant Human Glucagon receptor (GCGR) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli in vitro |
| Ursprungsart: | human |
| MW: | 54.1 kD |
ab 914,00 €
Glucagon receptor (GCGR), partial, human, recombinant
Artikelnummer: CSB-YP009316HU1.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 26-136aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: AQVMDFLFEK WKLYGDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPANT TANISCPWYL PWHHKVQHRF VFKRCGPDGQ WVRGPRGQPW RDASQCQMDG EEIEVQKEVA K. Purity: Greater than 90% as...
| Schlagworte: | GCGR, GL-R, Glucagon receptor, Recombinant Human Glucagon receptor (GCGR), partial |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 15.1 kD |
ab 395,00 €
Glucagon receptor (Gcgr), partial, mouse, recombinant
Artikelnummer: CSB-YP009316MO.1
Organism: Mus musculus (Mouse). Source: Yeast. Expression Region: 27-143aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: AQVMDFLFEK WKLYSDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPPNT TANISCPWYL PWYHKVQHRL VFKRCGPDGQ WVRGPRGQPW RNASQCQLDD EEIEVQKGVA KMYSSQQ. Purity: Greater than 90%...
| Schlagworte: | GL-R, Gcgr, Glucagon receptor, Recombinant Mouse Glucagon receptor (Gcgr), partial |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | mouse |
| MW: | 15.8 kD |
ab 283,00 €
Glucagon receptor (GCGR), partial, human, recombinant
Artikelnummer: CSB-EP009316HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 26-136aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: AQVMDFLFEK WKLYGDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPANT TANISCPWYL PWHHKVQHRF VFKRCGPDGQ WVRGPRGQPW RDASQCQMDG EEIEVQKEVA K....
| Schlagworte: | GCGR, GL-R, Glucagon receptor, Recombinant Human Glucagon receptor (GCGR), partial |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 20.5 kD |
ab 354,00 €
Glucagon receptor (Gcgr), partial, mouse, recombinant
Artikelnummer: CSB-EP009316MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 27-143aa. Protein Length: Partial. Tag Info: N-terminal GST-tagged. Target Protein Sequence: AQVMDFLFEK WKLYSDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPPNT TANISCPWYL PWYHKVQHRL VFKRCGPDGQ WVRGPRGQPW RNASQCQLDD EEIEVQKGVA KMYSSQQ. Purity: Greater than 90% as...
| Schlagworte: | GL-R, Gcgr, Glucagon receptor, Recombinant Mouse Glucagon receptor (Gcgr), partial |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 40.8 kD |
ab 283,00 €
Glucagon receptor (GCGR), partial (Active), human,...
Artikelnummer: CSB-MP009316HU1.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 26-136aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: AQVMDFLFEK WKLYGDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPANT TANISCPWYL PWHHKVQHRF VFKRCGPDGQ WVRGPRGQPW RDASQCQMDG EEIEVQKEVA...
| Schlagworte: | GCGR, GL-R, Glucagon receptor, Recombinant Human Glucagon receptor (GCGR), partial (Active) |
| Anwendung: | Active protein |
| Exprimiert in: | Mammalian cells |
| Ursprungsart: | human |
| MW: | 18.1 kD |
ab 293,00 €
Mazdutide
Artikelnummer: Cay40971-1
Mazdutide is a synthetic peptide derivative of the gut peptide hormone oxyntomodulin and a dual agonist of the glucagon-like peptide 1 receptor (GLP-1R) and glucagon receptor (GCGR). It reduces body weight in both Gcgr-/- and Glp1r-/- mice.Formal Name:...
| Schlagworte: | IBI362, LY3305677,... |
| Anwendung: | GLP-1R / GCGR dual agonist, synthetic peptide |
| CAS | 2259884-03-0 |
| MW: | 4563.1 D |
ab 101,00 €
L-168,049
Artikelnummer: Cay41112-10
L-168,049 is a glucagon receptor (GCGR) antagonist (IC50s = 3.7 and 179 nM in the absence and presence of MgCl2, respectively). It prevents glucagon-induced increases in IL-1beta and IL-6 levels in, and levels secreted from, HepG2 cells when used at a concentration of 3.7 nM. L-168,049 inhibits glucagon-induced...
| Schlagworte: | GCGR Antagonist II, Glucagon Receptor Antagonist II,... |
| Anwendung: | GCGR antagonist |
| CAS | 191034-25-0 |
| MW: | 467.8 D |
ab 114,00 €
Human GCGR Protein, hFc Tag
Artikelnummer: DIM-PME100722.10
Recombinant human GCGR protein with C-terminal human Fc tag. GCGR(Ala26-Lys136) hFc(Glu99-Ala330), Protein function: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting...
| Schlagworte: | GL-R |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 39.2 kD |
ab 95,00 €