Zu "K04527" wurden 128 Artikel gefunden!
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Anti-INSR
Artikelnummer: ABS-KC-2818.100
Protein function: Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated...
| Schlagworte: | Anti-Insulin receptor, Anti-IR, Anti-CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha, Anti-Insulin... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
INSR (human), recombinant protein
Artikelnummer: ABS-PP-097.20
| Schlagworte: | Insulin receptor, IR, CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha, Insulin receptor subunit beta],... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 19.5 kD |
ab 90,00 €
INSR (human), recombinant protein
Artikelnummer: ABS-PP-098.20
| Schlagworte: | Insulin receptor, IR, CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha, Insulin receptor subunit beta],... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 51.5 kD |
ab 90,00 €
Insulin (human)
Artikelnummer: TGM-T8221-25mg
Description: Insulin (human) is a peptide hormone that promotes glycogen synthesis and regulates glucose levels in the blood. Insulin (human) has hypoglycemic activity and is used clinically to treat hyperglycemia in diabetic patients. Target: IGF-1R. Smiles:...
| Schlagworte: | INSULIN, Insulin(human) |
| Anwendung: | Targets insulin receptor [EC:2.7.10.1] (INSR, CD220) |
| CAS | 11061-68-0 |
| MW: | 5807.57 D |
ab 31,00 €
HNMPA
Artikelnummer: TGM-T21761-1mg
Description: HNMPA is a membrane impermeable inhibitor of insulin receptor tyrosine kinase. HNMPA inhibits tyrosine and serine autophosphorylation by the human insulin receptor. HNMPA exhibits no effect on cyclic AMP-dependent protein kinase or protein kinase C activities. Target: IGF-1R. Smiles:...
| Anwendung: | Cell impermeable tyrosine kinase inhibitor |
| CAS | 132541-52-7 |
| MW: | 238.18 D |
ab 43,00 €
HNMPA-(AM)3
Artikelnummer: TGM-T36584-2mg
Description: HNMPA-(AM)3 inhibits activation of ERK phosphorylation and stimulation of ecdysteroid production by prothyrotropin (PTTH). Furthermore, HNMPA-(AM)3 had inhibitory effects on ecdysteroid production (IC50=14.2 µM) and insulin receptor activity (IC50=14.2 µM and 200 µM, in mosquitoes and mammals,...
| Anwendung: | Cell-permeable insulin receptor inhibitor prodrug |
| CAS | 120944-03-8 |
| MW: | 454.36 D |
195,00 €
GSK1904529A
Artikelnummer: TGM-T6003-10mg
Description: GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) . Target: IGF-1R, Apoptosis, Raf, Syk, VEGFR. Smiles: CCc1cc(Nc2nccc(n2)-c2c(nc3ccccn23)-c2ccc(OC)c(c2)C(=O)Nc2c(F)cccc2F)c(OC)cc1N1CCC(CC1)N1CCN(CC1)S(C)(=O)=O. References: Sabbatini P, et al. Clin Cancer Res,...
| Schlagworte: | GSK 4529 |
| Anwendung: | Insulin receptor / IGF-1R dual inhibitor |
| CAS | 1089283-49-7 |
| MW: | 851.96 D |
ab 34,00 €
Insulin Receptor Protein, Human, Recombinant (long...
Artikelnummer: TGM-TMPY-01146-100ug
Description: Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
| Schlagworte: | HHF5, CD220, insulin receptor |
| MW: | 107 kD |
ab 385,00 €
Insulin Receptor Protein, Human, Recombinant (short...
Artikelnummer: TGM-TMPY-01149-100ug
Description: Insulin Receptor Protein, Human, Recombinant (short isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 106 kDa and the accession number is P06213-2.
| Schlagworte: | CD220, Insulin Receptor, HHF5 |
| MW: | 106 kD |
ab 599,00 €
Insulin Receptor Protein, Human, Recombinant (long...
Artikelnummer: TGM-TMPY-05283-100ug
Description: Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
| Schlagworte: | HHF5, Insulin Receptor, CD220 |
| MW: | 107 kD |
ab 304,00 €
Insulin Receptor Protein, Human, Recombinant (His & GST)
Artikelnummer: TGM-TMPY-04395-50ug
Description: Insulin Receptor Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 72.3 kDa and the accession number is P06213-1.
| Schlagworte: | CD220, insulin receptor, HHF5 |
| MW: | 72.3 kD |
497,00 €
Anti-Insulin Receptor
Artikelnummer: ARG67129.100
Protein function: Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated...
| Schlagworte: | Anti-IR, Anti-INSR, Anti-CD220, Anti-Insulin receptor, Anti-Insulin receptor subunit beta, Anti-Insulin receptor subunit... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, swine |
616,00 €