Zu "K04527" wurden 122 Artikel gefunden!
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HNMPA
Artikelnummer: TGM-T21761-1mg
Description: HNMPA is a membrane impermeable inhibitor of insulin receptor tyrosine kinase. HNMPA inhibits tyrosine and serine autophosphorylation by the human insulin receptor. HNMPA exhibits no effect on cyclic AMP-dependent protein kinase or protein kinase C activities. Target: IGF-1R. Smiles:...
| Anwendung: | Cell impermeable tyrosine kinase inhibitor |
| CAS | 132541-52-7 |
| MW: | 238.18 D |
ab 45,00 €
HNMPA-(AM)3
Artikelnummer: TGM-T36584-2mg
Description: HNMPA-(AM)3 inhibits activation of ERK phosphorylation and stimulation of ecdysteroid production by prothyrotropin (PTTH). Furthermore, HNMPA-(AM)3 had inhibitory effects on ecdysteroid production (IC50=14.2 µM) and insulin receptor activity (IC50=14.2 µM and 200 µM, in mosquitoes and mammals,...
| Anwendung: | Cell-permeable insulin receptor inhibitor prodrug |
| CAS | 120944-03-8 |
| MW: | 454.36 D |
200,00 €
GSK1904529A
Artikelnummer: TGM-T6003-10mg
Description: GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) . Target: IGF-1R, Apoptosis, Raf, Syk, VEGFR. Smiles: CCc1cc(Nc2nccc(n2)-c2c(nc3ccccn23)-c2ccc(OC)c(c2)C(=O)Nc2c(F)cccc2F)c(OC)cc1N1CCC(CC1)N1CCN(CC1)S(C)(=O)=O. References: Sabbatini P, et al. Clin Cancer Res,...
| Schlagworte: | GSK 4529 |
| Anwendung: | Insulin receptor / IGF-1R dual inhibitor |
| CAS | 1089283-49-7 |
| MW: | 851.96 D |
ab 36,00 €
Insulin Receptor Protein, Human, Recombinant (long...
Artikelnummer: TGM-TMPY-01146-100ug
Description: Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
| Schlagworte: | HHF5, CD220, insulin receptor |
| MW: | 107 kD |
ab 386,00 €
Insulin Receptor Protein, Human, Recombinant (short...
Artikelnummer: TGM-TMPY-01149-100ug
Description: Insulin Receptor Protein, Human, Recombinant (short isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 106 kDa and the accession number is P06213-2.
| Schlagworte: | CD220, Insulin Receptor, HHF5 |
| MW: | 106 kD |
ab 599,00 €
Insulin Receptor Protein, Human, Recombinant (long...
Artikelnummer: TGM-TMPY-05283-100ug
Description: Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
| Schlagworte: | HHF5, Insulin Receptor, CD220 |
| MW: | 107 kD |
ab 311,00 €
Insulin Receptor Protein, Human, Recombinant (His & GST)
Artikelnummer: TGM-TMPY-04395-50ug
Description: Insulin Receptor Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 72.3 kDa and the accession number is P06213-1.
| Schlagworte: | CD220, insulin receptor, HHF5 |
| MW: | 72.3 kD |
497,00 €
Anti-Insulin Receptor
Artikelnummer: ARG67129.100
Protein function: Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated...
| Schlagworte: | Anti-IR, Anti-INSR, Anti-CD220, Anti-Insulin receptor, Anti-Insulin receptor subunit beta, Anti-Insulin receptor subunit... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, swine |
616,00 €
Anti-INSR
Artikelnummer: CSB-PA003043.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-INSR, EC=2.7.10.1, CD220 antibody, HHF5 antibody, human insulin receptor antibody, Insr antibody, INSR_HUMAN... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 126,00 €
Anti-Phospho-INSR (Y1355)
Artikelnummer: CSB-PA011225.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-INSR, EC=2.7.10.1, CD220 antibody, HHF5 antibody, human insulin receptor antibody, Insr antibody, INSR_HUMAN... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 126,00 €
Anti-Phospho-INSR (Y1361)
Artikelnummer: CSB-PA011226.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-INSR, EC=2.7.10.1, CD220 antibody, HHF5 antibody, human insulin receptor antibody, Insr antibody, INSR_HUMAN... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-Phospho-INSR (Thr1375)
Artikelnummer: CSB-PA994563.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits with...
| Schlagworte: | Anti-phospho-INSR, EC=2.7.10.1, CD220 antibody, HHF5 antibody, human insulin receptor antibody, Insr antibody, INSR_HUMAN... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
340,00 €