Zu "K04456" wurden 558 Artikel gefunden!
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Anti-AKT3
Artikelnummer: ABS-KC-2766.100
Protein function: AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range...
| Schlagworte: | Anti-RAC-gamma serine/threonine-protein kinase, Anti-Protein kinase Akt-3, Anti-Protein kinase B gamma, Anti-PKB gamma,... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-AKT3
Artikelnummer: ABS-KC-3409.100
Protein function: AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range...
| Schlagworte: | Anti-RAC-gamma serine/threonine-protein kinase, Anti-Protein kinase Akt-3, Anti-Protein kinase B gamma, Anti-PKB gamma,... |
| Anwendung: | IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
MK-2206 dihydrochloride
Artikelnummer: TGM-T1952-2mg
Description: MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and selective potency. MK-2206 dihydrochloride exhibits antitumor activity. Target: Apoptosis, Akt, Autophagy. Smiles:...
| Schlagworte: | MK-2206 2HCl |
| Anwendung: | Allosteric Akt inhibitor |
| CAS | 1032350-13-2 |
| MW: | 480.39 D |
ab 31,00 €
Miransertib
Artikelnummer: TGM-T3467-100mg
Description: Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor. Target: Akt, Parasite. Smiles: Nc1ncccc1-c1nc2ccc(nc2n1-c1ccc(cc1)C1(N)CCC1)-c1ccccc1. References: Yu Y, et al. PLoS One. 2015, 10(10):e20140479.
| Schlagworte: | AKT inhibitor 2, ARQ-092 |
| Anwendung: | Targets RAC serine/threonine-protein kinase [EC:2.7.11.1] (AKT) |
| CAS | 1313881-70-7 |
| MW: | 432.52 D |
ab 45,00 €
SC66
Artikelnummer: TGM-T3132-10mg
Description: SC66 is a AKT inhibitor in HepG2, HA22T/VGH, and PLC/PRF/5 cells (IC50: about 0.75 µg/ml, at 72 h). Target: Apoptosis, Akt. Smiles: O=C1\C(CCC\C1=C/c1ccncc1)=C\c1ccncc1. References: Cusimano A, et al. Oncotarget. 2015 Jan 30,6(3):1707-22.
| Anwendung: | AKT inhibitor |
| CAS | 871361-88-5 |
| MW: | 276.33 D |
ab 42,00 €
AKT inhibitor VIII
Artikelnummer: TGM-T3346-100mg
Description: AKT inhibitor VIII (AKTi-1/2) is a highly specific inhibitor of Akt1/2, with IC50 values of 58 nM and 210 nM respectively, demonstrating approximately 36-fold greater selectivity for Akt1 over Akt3. Target: Apoptosis, Akt. Smiles: O=c1[nH]c2ccccc2n1C1CCN(Cc2ccc(cc2)-c2nc3cc4[nH]cnc4cc3nc2-c2ccccc2)CC1....
| Schlagworte: | AKTi-1/2 |
| Anwendung: | Akt1/Akt2 inhibitor |
| CAS | 612847-09-3 |
| MW: | 551.64 D |
ab 45,00 €
CAY10567
Artikelnummer: TGM-T36086-100mg
Description: CAY10567 has a wide range of applications in life science related research. Target: Others. Smiles: OC(=O)C1=CC=C2N=C(C3=CC=CC=C3)C(=NC2=C1)C1=CC=CC=C1
| Anwendung: | Akt1 translocation inhibitor |
| CAS | 32387-96-5 |
| MW: | 326.35 D |
ab 67,00 €
Isobavachalcone
Artikelnummer: TGM-T3861-100mg
Description: Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in brain diseases associated with inflammation. Target: Autophagy, Apoptosis, Akt, Reactive Oxygen Species, Others. Smiles:...
| Schlagworte: | Corylifolinin, Isobacachalcone |
| Anwendung: | Akt1 inibitor |
| CAS | 20784-50-3 |
| MW: | 324.37 D |
ab 55,00 €
AKT-IN-1
Artikelnummer: TGM-T4489-100mg
Description: AKT-IN-1 (AZD-26) is an allosteric AKT inhibitor (IC50: 1.04 µM). Target: Akt. Smiles: NC(=O)c1cnc(-c2ccc(cc2)C2(N)CCC2)c(c1)-c1ccccc1. References: Kettle JG, et al. Diverse heterocyclic scaffolds as allosteric inhibitors of AKT. J Med Chem. 2012 Feb 9,55(3):1261-73.
| Schlagworte: | AZD26, AZD-26, AZD 26 |
| Anwendung: | AKT inhibitor |
| CAS | 1357158-81-6 |
| MW: | 343.42 D |
ab 114,00 €
Ipatasertib
Artikelnummer: TGM-T6252-100mg
Description: Ipatasertib (GDC-0068) (GDC-0068), a highly specific pan-Akt inhibitor, targets Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, respectively. Target: Akt. Smiles: C[C@H]1C2=C(N=CN=C2[C@H](O)C1)N3CCN(C([C@H](CNC(C)C)C4=CC=C(Cl)C=C4)=O)CC3. References: Lin K. Cancer Res, 2011, 71(8 Supplement), abstract DDT02-01.
| Schlagworte: | GDC-0068, RG7440 |
| Anwendung: | Targets RAC serine/threonine-protein kinase [EC:2.7.11.1] (AKT) |
| CAS | 1001264-89-6 |
| MW: | 458 D |
ab 40,00 €
Uprosertib
Artikelnummer: TGM-T6849-100mg
Description: Uprosertib (GSK2141795) (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2. Target: Akt. Smiles: Cn1ncc(Cl)c1-c1cc(oc1Cl)C(=O)NC(CN)Cc1ccc(F)c(F)c1. References: Pachl F, et al. J Proteome...
| Schlagworte: | GSK2141795, GSK795 |
| Anwendung: | Targets RAC serine/threonine-protein kinase [EC:2.7.11.1] (AKT) |
| CAS | 1047634-65-0 |
| MW: | 429.25 D |
ab 40,00 €
Miransertib mesylate
Artikelnummer: TGM-T70152-100mg
Description: Miransertib mesylate is a selective AKT inhibitor that binds to and inhibits the activity of AKT in a non-ATP competitive manner, which may result in the inhibition of the PI3K/AKT signaling pathway. This may result in reduction in tumor cell proliferation and the induction of tumor cell apoptosis....
| Anwendung: | Targets RAC serine/threonine-protein kinase [EC:2.7.11.1] (AKT) |
| CAS | 1817727-88-0 |
| MW: | 624.73 D |
ab 1.520,00 €