Zu "K04441" wurden 337 Artikel gefunden!
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SD 0006
Artikelnummer: TGM-T7276-100mg
Description: SD 0006 (SD-06) is a MAPK p38 alpha inhibitor with an IC50 of 110 nM, indicated for the treatment of arthritis. Target: p38 MAPK, Autophagy. Smiles: OCC(=O)N1CCC(CC1)c1n[nH]c(c1-c1ccncn1)-c1ccc(Cl)cc1. References: Walker J K , Selness S R , Devraj R V , et al. Identification of SD-0006, a potent diaryl...
| Schlagworte: | SD-06 |
| Anwendung: | p38alpha MAPK inhibitor |
| CAS | 271576-80-8 |
| MW: | 397.86 D |
ab 38,00 €
SB 239063
Artikelnummer: TGM-T6976-100mg
Description: SB 239063 (SB239063) is a potent and selective p38 MAPKalpha/beta inhibitor with IC50 of 44 nM, showing no activity against the gamma- and delta-kinase isoforms. Target: p38 MAPK, Autophagy. Smiles: COc1nccc(n1)-c1c(ncn1[C@H]1CC[C@H](O)CC1)-c1ccc(F)cc1. References: Underwood DC, et al. J Pharmacol Exp...
| Schlagworte: | SB239063 |
| Anwendung: | p38 MAPK inhibitor |
| CAS | 193551-21-2 |
| MW: | 368.4 D |
ab 43,00 €
R1487 Hydrochloride
Artikelnummer: TGM-T7162-2mg
Description: R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38alpha. Target: Autophagy, p38 MAPK. Smiles: Cl.Cn1c2nc(NC3CCOCC3)ncc2cc(Oc2ccc(F)cc2F)c1=O. References: Goldstein DM, Soth M, Gabriel T,et al.Discovery of...
| Schlagworte: | R1487 (Hydrochloride) |
| Anwendung: | p38alpha / MAPK14 inhibitor |
| CAS | 449808-64-4 |
| MW: | 424.83 D |
ab 65,00 €
Acumapimod
Artikelnummer: TGM-T7367-100mg
Description: Acumapimod (BCT-197) is an orally active inhibitor of p38alpha MAPK (IC50 <1 µM). Target: p38 MAPK, Autophagy. Smiles: Cc1ccc(cc1-n1ncc(C(=O)c2cccc(c2)C#N)c1N)C(=O)NC1CC1. References: Growcott E J , Bamba D , Galarneau J . R , et al. The effect of P38 MAP kinase inhibition in a mouse model of...
| Schlagworte: | BCT-197 |
| Anwendung: | p38 MAP kinase inhibitor |
| CAS | 836683-15-9 |
| MW: | 385.42 D |
ab 31,00 €
SD-169
Artikelnummer: TGM-T7661-100mg
Description: SD-169 (SD 169) is a selective and ATP competitive the MAP kinases p38alpha and p38beta inhibitor. Target: p38 MAPK. Smiles: NC(=O)c1ccc2[nH]ccc2c1. References: Myers R R , Sekiguchi Y , Kikuchi S , et al. Inhibition of p38 MAP kinase activity enhances axonal regeneration[J]. Experimental Neurology,...
| Schlagworte: | SD 169 |
| Anwendung: | MAP kinase p38alpha / p38beta inhibitor |
| CAS | 1670-87-7 |
| MW: | 160.17 D |
ab 30,00 €
p38alpha inhibitor 4
Artikelnummer: TGM-T78652-10mg
Description: p38alpha inhibitor 4 is a selective MAPK p38alpha inhibitor, which is used to study diabetes, pain and chronic inflammation. Target: p38 MAPK. Smiles: O=C1C=C(C=2C(=NNC2N1)C=3C=CC=C(C3)C(F)(F)F)C(F)(F)F. References: Kenneth M Comess, et al. Discovery and characterization of non-ATP site inhibitors of...
| Anwendung: | p38alpha inhibitor |
| CAS | 1262406-08-5 |
| MW: | 347.215 D |
ab 286,00 €
MAPK14 Protein, Mouse, Recombinant (His & Myc)
Artikelnummer: TGM-TMPH-02786-100ug
Description: MAPK14 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 48.6 kDa and the accession number is P47811.
| Schlagworte: | Mitogen-activated protein kinase p38 alpha, CRK1, Mitogen-activated protein kinase 14, Mapk14 |
| MW: | 48.6 kD |
ab 278,00 €
p38 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-04260-20ug
Description: MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. MAPK14 can be...
| Schlagworte: | SAPK2A, p38alpha, CSBP1, p38, CSBP2, EXIP, RK, PRKM14, mitogen-activated protein kinase 14, CSPB1, PRKM15, Mxi2, CSBP,... |
| MW: | 43.7 kD |
587,00 €
p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)
Artikelnummer: TGM-TMPY-04429-50ug
Description: p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.8 kDa and the accession number is P53778.
| Schlagworte: | ERK3, SAPK3, PRKM12, P38GAMMA, mitogen-activated protein kinase 12, ERK6, P38gamma, MAPK12, ERK-6, P38 gamma/MAPK12, SAPK-3 |
| MW: | 69.8 kD |
487,00 €
p38 gamma/MAPK12 Protein, Human, Recombinant
Artikelnummer: TGM-TMPY-04430-50ug
Description: p38 gamma/MAPK12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 42.1 kDa and the accession number is P53778.
| Schlagworte: | ERK6, P38gamma, ERK-6, P38GAMMA, MAPK12, ERK3, PRKM12, SAPK3, mitogen-activated protein kinase 12, P38 gamma/MAPK12, SAPK-3 |
| MW: | 42.1 kD |
487,00 €
p38 delta/MAPK13 Protein, Human, Recombinant (GST),...
Artikelnummer: TGM-TMPY-04531-50ug
Description: p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68.4 kDa and the accession number is O15264.
| Schlagworte: | PRKM13, MAPK13, P38 delta/MAPK13, p38delta, p38delta, MAPK-13, SAPK4, mitogen-activated protein kinase 13 |
| MW: | 68.4 kD |
487,00 €
p38 delta/MAPK13 Protein, Human, Recombinant (GST)
Artikelnummer: TGM-TMPY-04551-50ug
Description: p38 delta/MAPK13 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68.4 kDa and the accession number is O15264.
| Schlagworte: | PRKM13, p38delta, MAPK13, mitogen-activated protein kinase 13, MAPK-13, P38 delta/MAPK13, SAPK4, p38delta |
| MW: | 68.4 kD |
389,00 €