Zu "K04440" wurden 216 Artikel gefunden!
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Anti-MAPK8
Artikelnummer: ABS-KC-6167.100
Protein function: Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress- activated protein kinase/c-Jun N-terminal...
| Schlagworte: | Anti-Mitogen-activated protein kinase 8, Anti-MAP kinase 8, Anti-MAPK 8, Anti-JNK-46, Anti-Stress-activated protein kinase... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
ab 232,00 €
Anti-MAPK10
Artikelnummer: ATA-HPA068627.100
Polyclonal Antibody against Human MAPK10, Gene description: mitogen-activated protein kinase 10, Alternative Gene Names: JNK3, p493F12, p54bSAPK, PRKM10, Validated applications: ICC, WB, Uniprot ID: P53779, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function:...
| Schlagworte: | Anti-JNK3, Anti-SAPK1b, Anti-MAPK10, Anti-MAPK 10, EC=2.7.11.24, Anti-MAP kinase 10, Anti-MAP kinase p49 3F12, Anti-c-Jun... |
| Anwendung: | ICC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
450,00 €
Anti-MAPK9
Artikelnummer: ATA-HPA072462.100
Polyclonal Antibody against Human MAPK9, Gene description: mitogen-activated protein kinase 9, Alternative Gene Names: JNK2, p54a, PRKM9, SAPK, Validated applications: ICC, Uniprot ID: P45984, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function:...
| Schlagworte: | Anti-JNK2, Anti-MAPK9, Anti-JNK-55, Anti-SAPK1a, Anti-MAPK 9, Anti-MAP kinase 9, Anti-c-Jun N-terminal kinase 2,... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
450,00 €
Anti-JNK2
Artikelnummer: E-D-AB-10207L.100
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific...
| Schlagworte: | Anti-Jnk2, Anti-Mapk9, Anti-MAPK 9, Anti-p54-alpha, Anti-SAPK-alpha, Anti-MAP kinase 9, Anti-c-Jun N-terminal kinase 2,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 109,00 €
SU3327
Artikelnummer: TGM-T13018-100mg
Description: SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 µM). Target: JNK. Smiles: Nc1nnc(Sc2ncc(s2)[N+]([O-])=O)s1. References: De SK, et al. Design, synthesis, and structure-activity relationship of substrate competitive, selective, and in vivo active triazole and...
| Schlagworte: | halicin |
| Anwendung: | JNK1 inhibitor, antidiabetic, antibiotic agent |
| CAS | 40045-50-9 |
| MW: | 261.3 D |
ab 33,00 €
Tanzisertib
Artikelnummer: TGM-T14895-100mg
Description: Tanzisertib (CC-930) (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity. Target: JNK. Smiles: Cl.OC1CCC(CC1)Nc1ncc2nc(Nc3c(F)cc(F)cc3F)n([C@H]3CCOC3)c2n1. References: Plantevin Krenitsky V, et al. Discovery of CC-930, an orally active...
| Schlagworte: | CC-930 |
| Anwendung: | Targets mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] (JNK) |
| CAS | 899805-25-5 |
| MW: | 448.44 D |
ab 37,00 €
Bentamapimod
Artikelnummer: TGM-T2675-100mg
Description: Bentamapimod (AS 602801) is a novel, orally active inhibitor of JNK. Target: JNK. Smiles: N#C\C(=C1\Nc2ccccc2S1)c1ccnc(OCc2ccc(CN3CCOCC3)cc2)n1. References: Messoussi A, et al. Recent progress in the design, study, and development of c-Jun N-terminal kinase inhibitors as anticanceragents. Chem Biol....
| Schlagworte: | AS 602801 |
| Anwendung: | JNK1 / JNK2 / JNK3 inhibitor |
| CAS | 848344-36-5 |
| MW: | 457.55 D |
ab 40,00 €
JNK-IN-7
Artikelnummer: TGM-T3598-100mg
Description: JNK-IN-7 (JNK inhibitor) is a selective JNK1/2/3 inhibitor (IC50: 1.54/1.99/0.75 nM). It can also inhibit phosphorylation of c-Jun, which is a substrate of JNK kinase. Target: JNK. Smiles: CN(C)CC=CC(=O)Nc1cccc(c1)C(=O)Nc1ccc(Nc2nccc(n2)-c2cccnc2)cc1. References: Zhang T, et al. Discovery of Potent and...
| Schlagworte: | JNK inhibitor |
| Anwendung: | Potent, non-selective JNK inhibitor |
| CAS | 1408064-71-0 |
| MW: | 493.56 D |
ab 88,00 €
SP600125
Artikelnummer: TGM-T3109-100mg
Description: SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive properties. SP600125 inhibits autophagy and induces apoptosis. Target: Apoptosis, Aurora Kinase, Autophagy, Ferroptosis, JNK, Trk receptor....
| Schlagworte: | Nsc75890, Pyrazolanthrone, 1PMV, JNK Inhibitor II |
| Anwendung: | Reversible, ATP-competitive JNK1/JNK2/JNK3 inhibitor |
| CAS | 129-56-6 |
| MW: | 220.23 D |
ab 42,00 €
SP 600125, negative control
Artikelnummer: TGM-T38260-100mg
Description: SP 600125, negative control is a methylated analog of SP 600125 and can be used as a negative control for SP 600125. SP 600125, negative control inhibits DTP3 and GADD45beta/MKK7 (growth arrest and DNA damage-inducible beta/mediator-activated protein kinase kinase kinase 7) and is capable of restoring...
| Schlagworte: | JNK Inhibitor II, negative control |
| Anwendung: | Cell-permeable JNK inhibitor |
| CAS | 54642-23-8 |
| MW: | 234.25 D |
ab 40,00 €
JNK3 inhibitor-1
Artikelnummer: TGM-T40248-5mg
Description: JNK3 inhibitor-1 is a highly potent and selective compound that specifically inhibits JNK3 with an impressive IC50 value of 0.005 µM. In addition to its remarkable inhibitory effects, JNK3 inhibitor-1 possesses excellent oral bioavailability and the ability to efficiently penetrate the brain. Target:...
| Schlagworte: | JNK3 inhibitor-1 |
| Anwendung: | JNK3 inhibitor |
| CAS | 2622877-97-6 |
| MW: | 457.91 D |
1.370,00 €
CC-401 Hydrochloride
Artikelnummer: TGM-T5833-100mg
Description: CC-401 Hydrochloride (CC401 HCl) is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor (Ki of 25 to 50 nM.)with potential antineoplastic activity. Target: JNK. Smiles: Cl.C(CN1CCCCC1)Oc1cccc(c1)-c1n[nH]c2ccc(cc12)-c1ncn[nH]1. References: Vasilevskaya I A ,...
| Schlagworte: | CC401 HCl |
| Anwendung: | JNK inhibitor |
| CAS | 1438391-30-0 |
| MW: | 424.93 D |
ab 33,00 €