Zu "K04414" wurden 31 Artikel gefunden!
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NG 25 (hydrochloride hydrate)
Artikelnummer: Cay27579-1
NG 25 is a type II kinase inhibitor that inhibits MAP4K2 and TAK1 (IC50s = 21.7 and 149 nM, respectively). It also inhibits the Src family kinases Src and LYN (IC50s = 113 and 12.9 nM, respectively) and Abl family kinases (IC50s = 75.2 nM), as well as CSK, FER, and p38alpha (IC50s = 56.4, 82.3, and 102 nM,...
| Schlagworte: | N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-benzamide,... |
| Anwendung: | TAK1 (MAP3K7) inhibitor, MAP4K2 (GCK) inhibitor |
| MW: | 647 D |
ab 73,00 €
GCK (MAP4K2), GST-tag
Artikelnummer: BPS-40107
Human GCK, also known as MAP4K2, GenBank Accession No. NM_004579, full length, with N-terminal GST tag, MW ~125 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
| Schlagworte: | GCK, MAP4K2, MEKKK 2, GC kinase, EC=2.7.11.1, MEK kinase kinase 2, Germinal center kinase, Rab8-interacting protein,... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 125 kD |
862,00 €
Anti-MAP4K2
Artikelnummer: E-AB-10897.120
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha,...
| Schlagworte: | Anti-GCK, Anti-MAP4K2, Anti-MEKKK 2, Anti-GC kinase, EC=2.7.11.1, Anti-MEK kinase kinase 2, Anti-Germinal center kinase,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 71,00 €
GNF-7
Artikelnummer: Cay19918-1
GNF-7 is a multi-kinase inhibitor (IC50s = 25, 8, 61, 122, 136, and 133 nM for ACK1, GCK, Bcr-AblT315I, Bcr-AblE255V, Bcr-AblG250E, and c-Abl, respectively). It also inhibits several additional kinases in a panel by greater than 50% when used at a concentration of 10 µM. GNF-7 inhibits the growth of Ba/F3 cells...
| Schlagworte: | N-[3-[1,4-dihydro-1-methyl-7-[(6-methyl-3-pyridinyl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trif... |
| Anwendung: | Ack1 / GCK inhibitor |
| CAS | 839706-07-9 |
| MW: | 547.5 D |
ab 43,00 €
Anti-MAP4K2
Artikelnummer: E-AB-14677.120
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha,...
| Schlagworte: | Anti-GCK, Anti-MAP4K2, Anti-MEKKK 2, Anti-GC kinase, EC=2.7.11.1, Anti-MEK kinase kinase 2, Anti-Germinal center kinase,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 71,00 €
Anti-MAP4K2
Artikelnummer: ATA-HPA007330.100
Protein function: Serine/threonine-protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Acts as a MAPK kinase kinase kinase (MAP4K) and is an upstream activator of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway and to a lesser...
| Schlagworte: | Anti-GCK, Anti-MAP4K2, Anti-MEKKK 2, Anti-GC kinase, EC=2.7.11.1, Anti-MEK kinase kinase 2, Anti-Germinal center kinase,... |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 335,00 €
MAP4K2 protein (His tag), recombinant human
Artikelnummer: E-PDEH100398.100
Activity: Testing in progress Protein Construction: A DNA sequence encoding the Human MAP4K2 protein (Q12851-2) (Ile 501-Tyr 812) was expressed with a N-His&C-His. Sequence: Ile 501-Tyr 812. Fusion tag: N-His & C-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 35 kDa. Protein...
| Schlagworte: | GCK, MAP4K2, MEKKK 2, GC kinase, EC=2.7.11.1, MEK kinase kinase 2, Germinal center kinase, Rab8-interacting protein,... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 34.21 kD |
ab 81,00 €
NEU
Anti-MAP4K2
Artikelnummer: CSB-PA058535.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MAP4K2. Antigen Species: Human
| Schlagworte: | Anti-GCK, Anti-MAP4K2, Anti-MEKKK 2, Anti-GC kinase, EC=2.7.11.1, Anti-MEK kinase kinase 2, Anti-Germinal center kinase,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
NEU
Anti-MAP4K2
Artikelnummer: CSB-PA294869.50
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MAP4K2. Antigen Species: Human
| Schlagworte: | Anti-GCK, Anti-MAP4K2, Anti-MEKKK 2, Anti-GC kinase, EC=2.7.11.1, Anti-MEK kinase kinase 2, Anti-Germinal center kinase,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Human MAP4K2 Recombinant Protein (His tag)
Artikelnummer: G-RPES5657.20
Protein function: Serine/threonine-protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Acts as a MAPK kinase kinase kinase (MAP4K) and is an upstream activator of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway and to a lesser...
| Schlagworte: | GCK, MEKKK 2, GC kinase, MEK kinase kinase 2, Germinal center kinase, Rab8-interacting protein, MAPK/ERK kinase kinase... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
159,00 €
Recombinant Human MAP4K2/GC Kinase Protein (His & GST...
Artikelnummer: G-RPES1066.50
Human MAP4K2/GC Kinase Recombinant Protein (RPES1066) is a highly pure recombinant protein developed by Assay Genie for use in a range of applications Protein function: Serine/threonine-protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Acts as a MAPK kinase kinase...
| Schlagworte: | GCK, MAP4K2, MEKKK 2, GC kinase, EC=2.7.11.1, MEK kinase kinase 2, Germinal center kinase, Rab8-interacting protein,... |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
994,00 €
Anti-MAP4K2
Artikelnummer: E-AB-91806.120
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha,...
| Schlagworte: | GCK, MAP4K2, MEKKK 2, GC kinase, EC=2.7.11.1, MEK kinase kinase 2, Germinal center kinase, Rab8-interacting protein,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €