Zu "K04372" wurden 66 Artikel gefunden!
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ETC-206
Artikelnummer: TGM-T15250-100mg
Description: ETC-206 is a selective inhibitor of MNK1 and MNK2 (IC50s: 64 nM and 86 nM). Target: MNK. Smiles: O=C(N1CCOCC1)c1ccc(cc1)-c1ccc2ncc(-c3ccc(cc3)C#N)n2c1. References: Yang H, et al. Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast...
| Anwendung: | MKNK1 / MKNK2 inhibitor |
| CAS | 1464151-33-4 |
| MW: | 408.45 D |
ab 31,00 €
Tomivosertib
Artikelnummer: TGM-T3468-100mg
Description: Tomivosertib (eFT508) is a potent and highly selective MNK1 and MNK2 inhibitor with an IC50 value of 1-2 nM. Target: PD-1/PD-L1, MNK. Smiles: Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCCCC1. References: Kevin R Webster, et al. eFT508, a Potent and Selective Mitogen-Activated Protein Kinase Interacting...
| Schlagworte: | eFT508 |
| Anwendung: | Targets MAP kinase interacting serine/threonine kinase [EC:2.7.11.1] (MKNK, MNK) |
| CAS | 1849590-01-7 |
| MW: | 340.38 D |
ab 58,00 €
Merestinib
Artikelnummer: TGM-T3455-100mg
Description: Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity. Merestinib electively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell...
| Schlagworte: | LY2801653 |
| Anwendung: | Targets proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] (MET, HGFR) |
| CAS | 1206799-15-6 |
| MW: | 552.53 D |
ab 45,00 €
MNK inhibitor 9
Artikelnummer: TGM-T72752-100mg
Description: MNK Inhibitor 9 is a potent, selective inhibitor of MNK1/2, demonstrating IC50 values of 0.003 µM for both MNK1 and MNK2. It exhibits good cell permeability, making it suitable for tumor-related research. Target: Others. Smiles: CN1C2=C(C=CC=C2N=C1C3=NC(=CN=C3N)C4=CC(C(N(C)C)=O)=CC=N4)N5C[C@H](C)NCC5
| Anwendung: | MNK inhibitor |
| CAS | 1889336-59-7 |
| MW: | 471.56 D |
ab 1.786,00 €
CGP 57380
Artikelnummer: TGM-T6440-100mg
Description: CGP 57380 (MNK1 Inhibitor) is a potent MNK1 inhibitor with IC50 of 2.2 µM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases. Target: Apoptosis, MNK. Smiles: Nc1ncnc2[nH]nc(Nc3ccc(F)cc3)c12. References: Knauf U, et al. Mol Cell Biol. 2001, (16), 5500-5511.
| Schlagworte: | MNK1 Inhibitor |
| Anwendung: | MAPK-interacting kinase 1 inhibitor |
| CAS | 522629-08-9 |
| MW: | 244.23 D |
ab 39,00 €
MAP kinase-interacting serine/threonine-protein kinase 1...
Artikelnummer: CSB-EP861139HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-465aa. Protein Length: Full Length. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: MVSSQKLEKP IEMGSSEPLP IADGDRRRKK KRRGRATDSL PGKFEDMYKL TSELLGEGAY AKVQGAVSLQ NGKEYAVKII EKQAGHSRSR VFREVETLYQ CQGNKNILEL IEFFEDDTRF YLVFEKLQGG...
| Schlagworte: | Mnk1, MNK1, MKNK1, MAPK signal-integrating kinase 1, MAP kinase signal-integrating kinase 1, MAP kinase-interacting... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 58.2 kD |
ab 283,00 €
Anti-MKNK1
Artikelnummer: CSB-PA003260.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-MNK1, Anti-Mnk1, Anti-MKNK1, Anti-MAPK signal-integrating kinase 1, Anti-MAP kinase signal-integrating kinase 1,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 106,00 €
Anti-MKNK2
Artikelnummer: CSB-PA008946.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-Mnk2, Anti-GPRK7, Anti-MKNK2, EC=2.7.11.1, Anti-MAPK signal-integrating kinase 2, Anti-MAP kinase signal-integrating... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-MKNK1
Artikelnummer: CSB-PA070095.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-MNK1, Anti-Mnk1, Anti-MKNK1, Anti-MAPK signal-integrating kinase 1, Anti-MAP kinase signal-integrating kinase 1,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-MKNK1 (Ab-385)
Artikelnummer: CSB-PA114367.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-MNK1, Anti-Mnk1, Anti-MKNK1, Anti-MAPK signal-integrating kinase 1, Anti-MAP kinase signal-integrating kinase 1,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
275,00 €
Anti-MKNK1
Artikelnummer: CSB-PA167602.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-MNK1, Anti-Mnk1, Anti-MKNK1, Anti-MAPK signal-integrating kinase 1, Anti-MAP kinase signal-integrating kinase 1,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
275,00 €
Anti-Phospho-MKNK1 (Thr255)
Artikelnummer: CSB-PA913453.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits with...
| Schlagworte: | Anti-phospho-MNK1, Anti-phospho-Mnk1, Anti-phospho-MKNK1, Anti-phospho-MAPK signal-integrating kinase 1, Anti-phospho-MAP... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
330,00 €