Zu "K04369" wurden 144 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
PD 0325901
Artikelnummer: Cay13034-25
The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors. PD 0325901 is a potent MEK inhibitor that suppresses phosphorylation of ERK in mouse colon 26 tumors with an IC50 value of 0.33 nM. Suppression of ERK activation...
| Schlagworte: | N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide |
| Anwendung: | MEK inhibitor |
| CAS | 391210-10-9 |
| MW: | 482.2 D |
ab 58,00 €
MEK2 Protein, Human, Recombinant (GST)
Artikelnummer: TGM-TMPY-04544-50ug
Description: Dual specificity mitogen-activated protein kinase kinase 2, also known as MAP kinase kinase 2, MAPKK2, ERK activator kinase 2, MAPK / ERK kinase 2, MEK2 and MAP2K2, is a member of the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K2 / MEK2 contains...
| Schlagworte: | MEK2, PRKMK2, CFC4, MAPKK2, mitogen-activated protein kinase kinase 2, FLJ26075, MKK2 |
| MW: | 70.7 kD |
389,00 €
AZD8330
Artikelnummer: TGM-T6083-10mg
Description: AZD8330 (ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1. Target: ERK, MEK. Smiles: Cc1cc(C(=O)NOCCO)c(Nc2ccc(I)cc2F)n(C)c1=O. References: Wallace EM, et al. AACR Annual Meeting, 2009, Abst 3696.
| Schlagworte: | ARRY-704, ARRY-424704 |
| Anwendung: | MEK inhibitor |
| CAS | 869357-68-6 |
| MW: | 461.23 D |
ab 33,00 €
GSK1120212
Artikelnummer: LKT-G7440.5
GSK1120212 inhibits MEK1/2 and is currently in clinical trials as a potential treatment for melanoma. GSK1120212 exhibits anticancer chemotherapeutic activity, upregulating p27 expression and inhibiting growth in colorectal cancer cells and suppressing tumor growth in colorectal cancer xenografts.
| Schlagworte: | Trametinib, JTP-74057 |
| Anwendung: | MEK1/2 inhibitor |
| CAS | 871700-17-3 |
| MW: | 615.39 D |
ab 104,00 €
Anti-MAP2K2 Monoclonal
Artikelnummer: CSB-MA671424.100
Host Species: Mouse. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen....
| Schlagworte: | Anti-MEK2, Anti-MEK 2, Anti-MAP2K2, Anti-MAPKK 2, Anti-MAPK/ERK kinase 2, Anti-MAP kinase kinase 2, Anti-ERK activator... |
| Anwendung: | ELISA, WB, IHC, IF, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-Phospho-MAP2K2 (T394)
Artikelnummer: CSB-PA000570.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-MEK2, Anti-phospho-MEK 2, Anti-phospho-MAP2K2, Anti-phospho-MAPKK 2, Anti-phospho-MAPK/ERK kinase 2,... |
| Anwendung: | ELISA, WB, IHC, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-MAP2K2
Artikelnummer: CSB-PA030302.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-MEK2, Anti-MEK 2, Anti-MAP2K2, Anti-MAPKK 2, Anti-MAPK/ERK kinase 2, Anti-MAP kinase kinase 2, Anti-ERK activator... |
| Anwendung: | ELISA, WB, IHC, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-MAP2K2
Artikelnummer: CSB-PA04909A0Rb.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: MAP2K2. Antigen Species: Human
| Schlagworte: | Anti-MEK2, Anti-MEK 2, Anti-MAP2K2, Anti-MAPKK 2, Anti-MAPK/ERK kinase 2, Anti-MAP kinase kinase 2, Anti-ERK activator... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
Anti-Phospho-MAP2K2 (Thr394)
Artikelnummer: CSB-PA062510.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Schlagworte: | Anti-phospho-MEK2, Anti-phospho-MEK 2, Anti-phospho-MAP2K2, Anti-phospho-MAPKK 2, Anti-phospho-MAPK/ERK kinase 2,... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
330,00 €
Anti-MAP2K2
Artikelnummer: CSB-PA080229.100
Host Species: Rabbit. Isotype: IgG. Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity purification. Target Name: MAP2K2. Antigen Species: Human
| Schlagworte: | Anti-MEK2, Anti-MEK 2, Anti-MAP2K2, Anti-MAPKK 2, Anti-MAPK/ERK kinase 2, Anti-MAP kinase kinase 2, Anti-ERK activator... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-MAP2K2
Artikelnummer: CSB-PA097880.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MAP2K2. Antigen Species: Human
| Schlagworte: | Anti-MEK2, Anti-MEK 2, Anti-MAP2K2, Anti-MAPKK 2, Anti-MAPK/ERK kinase 2, Anti-MAP kinase kinase 2, Anti-ERK activator... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Anti-MAP2K2
Artikelnummer: CSB-PA101222.100
Host Species: Rabbit. Isotype: IgG. Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific...
| Schlagworte: | Anti-MEK2, Anti-MEK 2, Anti-MAP2K2, Anti-MAPKK 2, Anti-MAPK/ERK kinase 2, Anti-MAP kinase kinase 2, Anti-ERK activator... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 106,00 €