Zu "K04363" wurden 244 Artikel gefunden!
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AG-370
Artikelnummer: TGM-T21784-1mg
Description: AG 370, an indole tyrphostin, is a potent inhibitor of PDGF-induced mitogenesis with an IC50 of 20 µM, and it shows weak inhibition of the EGF receptor. Target: Others. Smiles: C(=C(C(=C(C#N)C#N)N)C#N)C=1C=C2C(=CC1)NC=C2
| Anwendung: | PDGF receptor kinase inhibitor |
| CAS | 134036-53-6 |
| MW: | 259.27 D |
ab 140,00 €
SU4312
Artikelnummer: TGM-T3570-10mg
Description: SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 µM respectively). SU4312 (SU 4312) unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS. Target: PDGFR, VEGFR....
| Schlagworte: | SU 4312, NSC 86429 |
| Anwendung: | Selective, cell-permeable VEGFR2 / PDGFR inhibitor |
| CAS | 5812-07-7 |
| MW: | 264.32 D |
ab 34,00 €
c-Kit-IN-1
Artikelnummer: TGM-T4332-100mg
Description: c-Kit-IN-1 (DCC-2618) is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM). Target: c-Kit, c-Met/HGFR. Smiles: Cn1cc(cn1)-c1cc(Oc2cc(F)c(NC(=O)C3(CC3)C(=O)Nc3ccccc3)cc2F)ccn1. References: Daniel L. Flynn, et al. Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative...
| Schlagworte: | PDGFR inhibitor 1, DCC-2618 |
| Anwendung: | KIT / PDGFR inhibitor |
| CAS | 1225278-16-9 |
| MW: | 489.47 D |
ab 38,00 €
Ripretinib
Artikelnummer: TGM-T8482-100mg
Description: Ripretinib (DCC-2618) is an orally bioavailable inhibitor of (KIT) and (PDGFRA). Target: PDGFR, FLT, Apoptosis, VEGFR, c-Kit. Smiles: CCn1c2cc(NC)ncc2cc(-c2cc(NC(=O)Nc3ccccc3)c(F)cc2Br)c1=O. References: Schneeweiss M, et al. The KIT and PDGFRA switch-control inhibitor DCC-2618 blocks growth and...
| Schlagworte: | DCC-2618 |
| Anwendung: | Targets proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1] (KIT, SCFR, CD117) |
| CAS | 1442472-39-0 |
| MW: | 510.36 D |
ab 67,00 €
PDGFRA Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-01139-100ug
Description: PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is P16234-1.
| Schlagworte: | platelet-derived growth factor receptor, alpha polypeptide, PDGFR2, platelet-derived growth factor receptor, alpha... |
| MW: | 57.7 kD |
ab 378,00 €
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)
Artikelnummer: TGM-TMPK-00419-100ug
Description: Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As...
| Schlagworte: | CD140A, RHEPDGFRA, PDGFR-2, PDGFRA, PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), PDGFR2, MGC74795 |
| MW: | 59.2 kD |
ab 282,00 €
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His &...
Artikelnummer: TGM-TMPK-00420-100ug
Description: Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As...
| Schlagworte: | RHEPDGFRA, PDGFRA, PDGFR2, PDGFR-2, MGC74795, CD140A, PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi),... |
| MW: | 59.2 kD |
ab 798,00 €
PDGFRA Protein, Human, Recombinant (hFc)
Artikelnummer: TGM-TMPY-00900-100ug
Description: PDGFRA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.9 kDa and the accession number is P16234-1.
| Schlagworte: | CD140A, platelet-derived growth factor receptor, alpha polypeptide, PDGFR2, RHEPDGFRA, PDGFR-2, platelet-derived growth... |
| MW: | 82.9 kD |
ab 587,00 €
PDGFRA Protein, Rat, Recombinant (His)
Artikelnummer: TGM-TMPY-03825-100ug
Description: PDGFRA Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is A6JD04.
| Schlagworte: | platelet-derived growth factor receptor, alpha polypeptide, platelet-derived growth factor receptor, alpha polypeptide |
| MW: | 57.6 kD |
686,00 €
PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
Artikelnummer: TGM-TMPY-05608-100ug
Description: PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 59.4 kDa and the accession number is P16234-1.
| Schlagworte: | platelet-derived growth factor receptor, alpha polypeptide, PDGFR-2, PDGFR2, CD140A, RHEPDGFRA, platelet-derived growth... |
| MW: | 59.4 kD |
ab 452,00 €
PDGFRA Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPY-05787-1mg
Description: PDGFRA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.87 kDa and the accession number is P26618-2.
| Schlagworte: | platelet-derived growth factor receptor, alpha polypeptide, AI115593, Pdgfr-2, platelet-derived growth factor receptor,... |
| MW: | 57.87 kD |
ab 349,00 €
PDGFRA Protein, Mouse, Recombinant (hFc)
Artikelnummer: TGM-TMPY-05789-1mg
Description: PDGFRA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.15 kDa and the accession number is P26618-2.
| Schlagworte: | CD140a, platelet-derived growth factor receptor, alpha polypeptide, Pdgfr-2, platelet-derived growth factor receptor,... |
| MW: | 83.15 kD |
ab 349,00 €