Zu "K04362" wurden 204 Artikel gefunden!
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FGFR1, active human recombinant protein
Artikelnummer: BPS-40210
Active recombinant human FGFR1 (399-822) was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. The gene accession number is NM_023110. Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
| Schlagworte: | N-sam, CD331, BFGFR, FLT-2, FGFR1, FGFR-1, bFGF-R-1, Proto-oncogene c-Fgr, Fms-like tyrosine kinase 2, Fibroblast growth... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 73 kD |
901,00 €
FGFR1c/beta-Klotho Reporter Assay System (mouse)
Artikelnummer: IB-M22001
This is an all-inclusive cell-based luciferase reporter assay kit targeting the Human Hepatocyte Nuclear Factor 4 alpha (NR2A1, HNF4a). INDIGO's HNF4a reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the HNF4a. In addition to HNF4a Reporter Cells,...
| Schlagworte: | Flg, MFR, Fgfr1, CD331, FGFR-1, bFGF-R-1, Proto-oncogene c-Fgr, Fibroblast growth factor receptor 1, Basic fibroblast... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | mouse |
ab 1.507,00 €
ASP5878
Artikelnummer: Cay41841-1
ASP5878 is an inhibitor of wild-type FGFR1, -2, -3, and -4 (IC50s = 0.47, 0.6, 0.74, and 3.5 nM, respectively) and mutant FGFR3K650E, FGFR3K560M, and FGFR4N535K (IC50s = 1.6, 4.2, and 78 nM, respectively). It is selective for these FGFRs over a panel of 128 additional kinases at 200 nM but does inhibit VEGFR2 and...
| Schlagworte: | 4-[[5-[(2,6-difluoro-3,5-dimethoxyphenyl)methoxy]-2-pyrimidinyl]amino]-1H-pyrazole-1-ethanol |
| Anwendung: | Wild-type/mutant FGFR inhibitor |
| CAS | 1453208-66-6 |
| MW: | 407.4 D |
ab 54,00 €
Nintedanib
Artikelnummer: TGM-T1777-50mg
Description: Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFRalpha, and PDGFRbeta (IC50=59/65 nM). Nintedanib has antitumor activity and inhibits tumor growth by inhibiting angiogenesis....
| Schlagworte: | BIBF 1120, Intedanib |
| Anwendung: | Targets FMS-like tyrosine kinase 1 [EC:2.7.10.1] (FLT1, VEGFR1) |
| CAS | 656247-17-5 |
| MW: | 539.62 D |
ab 40,00 €
FGFR1 Protein, Human, Recombinant (E. coli, His)
Artikelnummer: TGM-TMPH-01336-100ug
Description: FGFR1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 43.4 kDa and the accession number is P11362.
| Schlagworte: | Basic fibroblast growth factor receptor 1, Proto-oncogene c-Fgr, N-sam, Fibroblast growth factor receptor 1, Fms-like... |
| MW: | 43.4 kD |
ab 198,00 €
FGFR1 Protein, Human, Recombinant (Yeast, His)
Artikelnummer: TGM-TMPH-01337-100ug
Description: FGFR1 Protein, Human, Recombinant (Yeast, His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 41.4 kDa and the accession number is P11362.
| Schlagworte: | Fms-like tyrosine kinase 2, Proto-oncogene c-Fgr, N-sam, FGFR1, Fibroblast growth factor receptor 1, Basic fibroblast... |
| MW: | 41.4 kD |
ab 229,00 €
FGFR1 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-01011-100ug
Description: FGFR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is H9FRD4.
| Schlagworte: | FLT2, FGFBR, KAL2, HRTFDS, OGD, BFGFR, FLT-2, HH2, N-SAM, FGFR-1, HBGFR, FLG, bFGF-R-1, CD331, CEK, fibroblast growth... |
| MW: | 31 kD |
ab 385,00 €
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
Artikelnummer: TGM-TMPK-00392-100ug
Description: Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective...
| Schlagworte: | FGFR-1, CD331, BFGFR, FLT-2, N-sam, bFGF-R-1, FGFR1 beta (IIIc) |
| MW: | 25.23 kD |
ab 345,00 €
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
Artikelnummer: TGM-TMPK-00393-100ug
Description: FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.
| Schlagworte: | FGF R1a, FGFR1 alpha (IIIc), FGFR1 alpha, FGFR1 alpha |
| MW: | 42 kD |
ab 229,00 €
FGFR1 beta (IIIc) Protein, Human, Recombinant (His &...
Artikelnummer: TGM-TMPK-00394-100ug
Description: Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective...
| Schlagworte: | FGFR-1, CD331, bFGF-R-1, N-sam, FGFR1 beta (IIIc), BFGFR, FLT-2 |
| MW: | 25.23 kD |
ab 814,00 €
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His &...
Artikelnummer: TGM-TMPK-00395-100ug
Description: FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.
| Schlagworte: | FGF R1a, FGFR1 alpha, FGFR1 alpha (IIIc), FGFR1 alpha |
| MW: | 42 kD |
ab 814,00 €
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)
Artikelnummer: TGM-TMPY-06033-200ug
Description: FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56 kDa and the accession number is H9FRD4.
| Schlagworte: | HBGFR, BFGFR, FLG, bFGF-R-1, fibroblast growth factor receptor 1, FGFR-1, HRTFDS, OGD, CEK, N-SAM, CD331, FLT2, KAL2, HH2,... |
| MW: | 56 kD |
903,00 €