Zu "K04361" wurden 759 Artikel gefunden!
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Erlotinib
Artikelnummer: Cay10483-250
Erlotinib is an EGFR inhibitor (Ki = 2.7 nM). It is greater than 1,000-fold selective for EGFR over Src and Abl at 0.1 µM. Erlotinib induces caspase-3 and -7 activity in NCI H358 non-small cell lung cancer (NSCLC) cells when used at a concentration of 1 µM. Erlotinib (25 mg/kg) reduces EGF-induced EGFR...
| Schlagworte: | NSC 718781, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 183321-74-6 |
| MW: | 393.4 D |
ab 43,00 €
Epidermal growth factor receptor (EGFR), partial, human,...
Artikelnummer: CSB-EP007479HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 25-645aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: LEEKKVCQGT SNKLTQLGTF EDHFLSLQRM FNNCEVVLGN LEITYVQRNY DLSFLKTIQE VAGYVLIALN TVERIPLENL QIIRGNMYYE NSYALAVLSN YDANKTGLKE...
| Schlagworte: | ERBB, EC=2.7.10.1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-1,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 73.6 kD |
ab 213,00 €
Epidermal growth factor receptor (EGFR), partial, human,...
Artikelnummer: CSB-EP007479HU3.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 669-684aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Target Protein Sequence: RRRHIVRKRT LRRLLQ. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a....
| Schlagworte: | ERBB, EC=2.7.10.1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-1,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 22.2 kD |
ab 213,00 €
Epidermal growth factor receptor (EGFR), partial,...
Artikelnummer: CSB-MP007479HU-B.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 25-645aa. Protein Length: Partial. Tag Info: C-terminal mFc-Avi-tagged. Target Protein Sequence: LEEKKVCQGT SNKLTQLGTF EDHFLSLQRM FNNCEVVLGN LEITYVQRNY DLSFLKTIQE VAGYVLIALN TVERIPLENL QIIRGNMYYE NSYALAVLSN YDANKTGLKE LPMRNLQEIL HGAVRFSNNP...
| Schlagworte: | ERBB, EC=2.7.10.1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-1,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Mammalian cells |
| Ursprungsart: | human |
| MW: | 97.6 kD |
ab 388,00 €
Epidermal growth factor receptor (EGFR), partial...
Artikelnummer: CSB-MP007479HU.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 25-645aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: LEEKKVCQGT SNKLTQLGTF EDHFLSLQRM FNNCEVVLGN LEITYVQRNY DLSFLKTIQE VAGYVLIALN TVERIPLENL QIIRGNMYYE NSYALAVLSN YDANKTGLKE...
| Schlagworte: | ERBB, EC=2.7.10.1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-1,... |
| Anwendung: | Active protein |
| Exprimiert in: | Mammalian cells |
| Ursprungsart: | human |
| MW: | 73.6 kD |
ab 216,00 €
RX-518
Artikelnummer: Cay40922-10
RX-518 is an inhibitor of EGFR. It inhibits the growth of A431, H1975, and HCC827 cancer cells expressing wild-type EGFR, EGFR L858R/T790M, and EGFR del19, respectively (GI50s = 5, 10, and 689 nM, respectively).Formal Name:...
| Schlagworte: | CK-101, Olafertinib,... |
| Anwendung: | EGFR inhibitor |
| CAS | 1660963-42-7 |
| MW: | 530.6 D |
ab 114,00 €
Human EGFR Protein, His Tag
Artikelnummer: DIM-PME100099.10
Recombinant human EGFR Protein with C-terminal 6×His tag. EGFR(Leu25-Ser645) 6×His tag, Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725,...
| Schlagworte: | EGFR, ERBB, ERBB1, HER1, PIG61, mENA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 69.4 kD |
ab 115,00 €
Anti-EGFRVIII antibody(2E12), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101040.10
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin,...
| Schlagworte: | Anti-EGFR, Anti-RBB, Anti-RBB1, Anti-ER1, Anti-IG61, Anti-ENA, Anti-EGFRVIII antibody(2E12), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
| CAS | 12 |
ab 139,00 €
Human EGFRVIII Protein, His Tag
Artikelnummer: DIM-PME101321.10
Recombinant Human EGFRVIII Protein with C-terminal 6×His tag. EGFRVIII(Leu25-Ser645 ?267aa) 6×His tag, Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960,...
| Schlagworte: | EGFR, ERBB, ERBB1, HER1, PIG61, mENA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 39.5 kD |
ab 98,00 €
Cynomolgus EGFR Protein, His Tag
Artikelnummer: DIM-PME-C100036.10
Recombinant Cynomolgus EGFR protein with C-terminal 10×His tag. EGFR(Leu25-Ser645) 10×His tag
| Schlagworte: | ERBB, ERRP, HER1, mENA, ERBB1, PIG61, NISBD2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | Cynomolgus |
| MW: | 70.0 kD |
ab 168,00 €
Mouse EGFR Protein, His Tag
Artikelnummer: DIM-PME-M100062.10
Recombinant mouse EGFR protein with C-terminal 6×His tag. Mouse EGFR(Leu25-Ser647) 6×His tag, Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:8404850). Known ligands...
| Schlagworte: | Epidermal growth factor receptor, Egfr |
| Exprimiert in: | Human cells |
| Ursprungsart: | mouse |
| MW: | 70.1 kD |
ab 144,00 €
Anti-EGFR Monoclonal
Artikelnummer: CSB-MA000199.100
Host Species: Mouse. Isotype: IgG. Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific...
| Schlagworte: | Anti-ERBB, EC=2.7.10.1, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 106,00 €