Zu "K04361" wurden 789 Artikel gefunden!
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Erlotinib
Artikelnummer: Cay10483-250
Erlotinib is an EGFR inhibitor (Ki = 2.7 nM). It is greater than 1,000-fold selective for EGFR over Src and Abl at 0.1 µM. Erlotinib induces caspase-3 and -7 activity in NCI H358 non-small cell lung cancer (NSCLC) cells when used at a concentration of 1 µM. Erlotinib (25 mg/kg) reduces EGF-induced EGFR...
| Schlagworte: | NSC 718781, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 183321-74-6 |
| MW: | 393.4 D |
ab 44,00 €
NEU
Anti-EGFR (depatuxizumab biosimilar) mAb
Artikelnummer: DIM-BME100252.100
Research use only. ELISA 1:5000-10000, Flow Cyt 1:100. Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include...
| Schlagworte: | ABT-806, Anti-ERBB, EC=2.7.10.1, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor... |
| Anwendung: | ELISA, FC |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 118,00 €
NEU
Anti-EGFR (QD6 biosimilar) mAb
Artikelnummer: DIM-BME100250.100
Research use only. ELISA 1:5000-10000, Flow Cyt 1:100. Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include...
| Schlagworte: | QD6,AZD9592 without cMet mAb, Anti-ERBB, EC=2.7.10.1, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor,... |
| Anwendung: | ELISA, FC |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 118,00 €
Anti-EGFR
Artikelnummer: ABS-KC-1091.100
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin,...
| Schlagworte: | Anti-Epidermal growth factor receptor, Anti-Proto-oncogene c-ErbB-1, Anti-Receptor tyrosine-protein kinase erbB-1, EGFR... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
Anti-EGFR
Artikelnummer: ABS-KC-1092.100
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin,...
| Schlagworte: | Anti-Epidermal growth factor receptor, Anti-Proto-oncogene c-ErbB-1, Anti-Receptor tyrosine-protein kinase erbB-1, EGFR... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
Anti-EGFR
Artikelnummer: ABS-KC-1679.100
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin,...
| Schlagworte: | Anti-Epidermal growth factor receptor, Anti-Proto-oncogene c-ErbB-1, Anti-Receptor tyrosine-protein kinase erbB-1, EGFR... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
Anti-EGFR
Artikelnummer: ABS-KC-6232.100
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin,...
| Schlagworte: | Anti-Epidermal growth factor receptor, Anti-Proto-oncogene c-ErbB-1, Anti-Receptor tyrosine-protein kinase erbB-1, EGFR... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
Anti-EGFR
Artikelnummer: ABS-KC-6242.100
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin,...
| Schlagworte: | Anti-Epidermal growth factor receptor, Anti-Proto-oncogene c-ErbB-1, Anti-Receptor tyrosine-protein kinase erbB-1, EGFR... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
Anti-EGFR
Artikelnummer: ABS-KC-6306.100
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin,...
| Schlagworte: | Anti-Epidermal growth factor receptor, Anti-Proto-oncogene c-ErbB-1, Anti-Receptor tyrosine-protein kinase erbB-1, EGFR... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
Anti-EGFR
Artikelnummer: ABS-KC-6307.100
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin,...
| Schlagworte: | Anti-Epidermal growth factor receptor, Anti-Proto-oncogene c-ErbB-1, Anti-Receptor tyrosine-protein kinase erbB-1, EGFR... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, monkey |
ab 232,00 €
Anti-EGFR
Artikelnummer: ABS-KC-6438.100
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin,...
| Schlagworte: | Anti-Epidermal growth factor receptor, Anti-Proto-oncogene c-ErbB-1, Anti-Receptor tyrosine-protein kinase erbB-1, EGFR... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, monkey |
ab 232,00 €
EGFR (T790M, C797S, L858R), GST-tag
Artikelnummer: BPS-40351
Human EGFR T790M, C797S, L858R (GenBank Accession No. NM_005228), (a.a. 668-1210) with N-terminal GST tag, MW = 88 kDa, expressed in baculovirus expression system.
| Schlagworte: | ERBB, EC=2.7.10.1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-1,... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Ursprungsart: | human |
| MW: | 88 kD |
551,00 €