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Zu "K04325" wurden 39 Artikel gefunden!
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Artikelnummer: ATA-HPA048933.100
Polyclonal Antibody against Human FFAR1, Gene description: free fatty acid receptor 1, Alternative Gene Names: FFA1R, GPR40, Validated applications: ICC, Uniprot ID: O14842, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: G-protein coupled receptor for...
Schlagworte: | Anti-GPR40, Anti-FFAR1, Anti-Free fatty acid receptor 1, Anti-G-protein coupled receptor 40 |
Anwendung: | ICC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
477,00 €
Artikelnummer: TGM-T17177-100mg
Description: TUG-424 significantly enhances glucose-stimulated insulin secretion at 100 nM. TUG-424 is a potent and selective free fatty acid receptor 1 agonist (EC50: 32 nM). Target: Others. Smiles: Cc1ccccc1C#Cc1ccc(CCC(O)=O)cc1. References: Discovery of Potent and Selective Agonists for the Free Fatty Acid...
Schlagworte: | TUG424 |
Anwendung: | FFAR1 agonist, GPR40 agonist |
CAS | 1082058-99-8 |
MW: | 264.32 D |
ab 74,00 €
Artikelnummer: TGM-T14216-10mg
Description: AMG 837 is a partial GPR40 agonist with an EC50 value of 13 nM, showcasing 85% of the maximal activity displayed by DHA in standard assay conditions, indicating its high potency and selectivity in vitro. This compound excels as a GPR40 agonist with a notable pharmacokinetic profile, effectively...
Anwendung: | Partial GPR40 agonist |
CAS | 865231-46-5 |
MW: | 438.44 D |
ab 93,00 €
Artikelnummer: TGM-T35816-10mg
Description: ZLY032 is a dual agonist of free fatty acid receptor 1 (FFAR1/GPR40, EC50= 68 nM in a FLIPR assay) and peroxisome proliferator-activated receptor delta (PPARdelta, EC50= 102 nM in a reporter assay).1It is selective for FFAR1 and PPARdelta over PPARalpha and PPARgamma (EC50s = >10 µM for both). ZLY032...
Anwendung: | Dual FFAR1 and PPARdelta agonist |
CAS | 2314465-67-1 |
MW: | 449.44 D |
ab 108,00 €
Artikelnummer: TGM-T7127-10mg
Description: DC260126 is a small-molecule antagonist of FFA1 (GPR40). Target: Apoptosis, GPR. Smiles: CCCCc1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1. References: Peng S , Ting W , Yuren Z , et al. DC260126: A Small-Molecule Antagonist of GPR40 that Protects against Pancreatic beta-Cells Dysfunction in db/db Mice[J]. PLoS ONE,...
Anwendung: | Free fatty acid receptor 1 (FFAR1/GPR40) antagonist |
CAS | 346692-04-4 |
MW: | 307.38 D |
ab 49,00 €
Artikelnummer: TGM-T73757-10mg
Description: Phytanic acid, an endogenous metabolite found in blood, is utilized in studying Zellweger Syndrome, Alpha Methylacyl CoA Racemase Deficiency, Rhizomelic Chondrodysplasia Punctata, and Infantile Refsum Disease [1] [2] [3] [4] [5]. Target: Others. Smiles: CC(C)CCCC(C)CCCC(C)CCCC(C)CC(O)=O
Anwendung: | Fatty acid metabolite of chlorophyll, RXR and PPAR agonist, potential GPR40 agonist |
CAS | 14721-66-5 |
MW: | 312.53 D |
ab 233,00 €
Artikelnummer: TGM-TQ0241-100mg
Description: TUG-770 is a GPR40/FFA1 agonist with potential anti-inflammatory activity.TUG-770 can be used to study type 2 diabetes, dementia, and Alzheimer's disease. Target: GPR. Smiles: OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N. References: Christiansen E, et al. Discovery of TUG-770: A Highly Potent Free Fatty Acid...
Schlagworte: | TUG 770, TUG770 |
Anwendung: | GPR40 agonist |
CAS | 1402601-82-4 |
MW: | 307.32 D |
ab 58,00 €
Artikelnummer: DIM-FLP100134.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
Schlagworte: | GPR40, FFAR1, Free fatty acid receptor 1, G-protein coupled receptor 40, FFA1R, GPCR40, GPR40, Human FFAR1 full length... |
Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
Exprimiert in: | Human cells |
Ursprungsart: | human |
MW: | 31.5 kD |
ab 1.291,00 €
Artikelnummer: CSB-PA008938.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-GPR40, Anti-FFAR1, Anti-Free fatty acid receptor 1, Anti-G-protein coupled receptor 40, FFA1R antibody, FFAR 1... |
Anwendung: | ELISA, WB, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, monkey |
ab 126,00 €
Artikelnummer: Cay10008908-5
GPR40 (free fatty acid receptor 1, FFAR1) is a G protein-coupled receptor (GPCR) that is activated by saturated and unsaturated long chain fatty acids. It is thought to play a role in the potentiation of insulin secretion by fatty acids in a glucose-sensitive manner. GW 1100 is a selective antagonist of...
Schlagworte: | 4-[5-[(2-ethoxy-5-pyrimidinyl)methyl]-2-[[(4-fluorophenyl)methyl]thio]-4-oxo-1(4H)-pyrimidinyl]-benzoic acid, ethyl ester |
Anwendung: | GPR40 antagonist |
CAS | 306974-70-9 |
MW: | 520.6 D |
ab 100,00 €
Artikelnummer: Cay601190-1
Free fatty acid receptor 1 (FFAR1)/GPR40 is a G protein-coupled receptor for long-chain fatty acids such as docosahexaenoic acid and eicosapentaenoic acid omega-3 fatty acids. It is involved in the regulation of insulin release from pancreatic beta cells and mediates triglyceride-induced secretion of incretins GLP-1...
Schlagworte: | Free Fatty Acid Receptor 1, G Protein-Coupled Receptor 40 |
Anwendung: | Cell based assays, HTS, reverse transfection reporter assay |
Spezies-Reaktivität: | human |
635,00 €
Artikelnummer: Cay21815-5
AMG 837 is a partial agonist of free fatty acid receptor 1 (FFAR1/GPR40). It induces calcium mobilization in CHO cells expressing FFAR1/GPR40 but not FFAR2/GPR43, FFAR3/GPR41, or FFAR4/GPR120 (EC50s = 0.0135, >10, >10, and >10 µM, respectively). AMG 837 induces insulin secretion in MIN6 pancreatic beta-cells and...
Schlagworte: | betaS-1-propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]-benzenepropanoic acid |
Anwendung: | Partial GPR40 agonist |
CAS | 865231-46-5 |
MW: | 438.4 D |
ab 52,00 €