Zu "K04322" wurden 57 Artikel gefunden!
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CYSLTR1 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-03749-100ug
Description: Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein...
| Schlagworte: | LTD4 receptor, HMTMF81, CYSLT1, CYSLTR1, CysLTR1, G-protein coupled receptor HG55, Cysteinyl leukotriene D4 receptor,... |
| MW: | 44.6 kD |
ab 1.961,00 €
Verlukast
Artikelnummer: TGM-T19674-100mg
Description: Verlukast is an (R)-enantiomer of MK-571 and a potent and selective LTD4 receptor antagonist. Verlukast showed [3H]leukotriene D4 binding in guinea-pig (IC50 = 3.1 +/- 0.5 nM) and human (IC50 = 8.0 +/- 3.0 nM) lung homogenates and dimethyl sulfoxide differentiated U937 cell membrane preparations (IC50 =...
| Schlagworte: | MK-679, MK 0679, L 668019, L-668,019, L 668,019, MK 679 |
| Anwendung: | Targets cysteinyl leukotriene receptor 1 (CYSLTR1) |
| CAS | 120443-16-5 |
| MW: | 515.09 D |
ab 754,00 €
Zafirlukast
Artikelnummer: TGM-T6736-100mg
Description: Zafirlukast (ICI 204219) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma. Target: Leukotriene Receptor. Smiles: COc1cc(ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12)C(=O)NS(=O)(=O)c1ccccc1C. References: Kassahun K, et al. Chem Res...
| Schlagworte: | Accolate, ICI 204219, Vanticon |
| Anwendung: | Targets cysteinyl leukotriene receptor 1 (CYSLTR1) |
| CAS | 107753-78-6 |
| MW: | 575.68 D |
ab 42,00 €
Montelukast
Artikelnummer: TGM-T1677-25mg
Description: Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury. Target: Lipoxygenase, Leukotriene Receptor, LTR. Smiles:...
| Schlagworte: | Singular |
| Anwendung: | Targets cysteinyl leukotriene receptor 1 (CYSLTR1) |
| CAS | 158966-92-8 |
| MW: | 586.18 D |
ab 30,00 €
Montelukast sodium
Artikelnummer: TGM-T1677L-100mg
Description: Montelukast sodium (MK0476) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury. Target: LTR, Leukotriene Receptor. Smiles:...
| Schlagworte: | MK0476 |
| Anwendung: | Targets cysteinyl leukotriene receptor 1 (CYSLTR1) |
| CAS | 151767-02-1 |
| MW: | 608.17 D |
ab 42,00 €
Tipelukast
Artikelnummer: TGM-T15647-10mg
Description: Tipelukast (KCA 757) is a novel, orally available leukotriene receptor antagonist with anti-inflammatory properties, capable of reducing fibrosis and down-regulating TIMP-1 and type 1 collagen. Tipelukast is utilized in asthma research. Target: Leukotriene Receptor. Smiles:...
| Schlagworte: | MN 001, KCA 757 |
| Anwendung: | Targets cysteinyl leukotriene receptor 1 (CYSLTR1) |
| CAS | 125961-82-2 |
| MW: | 530.67 D |
ab 322,00 €
Ablukast
Artikelnummer: TGM-T26519-1mg
Description: Ablukast (Ro 23-3544) is a leukotriene receptor antagonist that functions as an anti-asthmatic. Target: Leukotriene Receptor. Smiles: CCCc1c(O)c(ccc1OCCCCCOc1cc2OC(CCc2cc1C(C)=O)C(O)=O)C(C)=O. References: Rosenbach T, Csatò M, Czarnetzki BM. Studies on the role of leukotrienes in murine allergic and...
| Schlagworte: | Ro 23-3544 |
| Anwendung: | Targets cysteinyl leukotriene receptor 1 (CYSLTR1) |
| CAS | 96566-25-5 |
| MW: | 498.56 D |
ab 42,00 €
Dihydro Montelukast
Artikelnummer: TGM-T37386-1mg
Description: Dihydro montelukast is a potential impurity found in commercial montelukast preparations. Montelukast (sodium salt) is a potent and selective cysteinyl leukotriene 1 (CysLT1) receptor antagonist. Formulations containing montelukast are used for the treatment of asthma as well as for the symptoms...
| Anwendung: | Impurity |
| CAS | 142147-67-9 |
| MW: | 588.2 D |
ab 242,00 €
CAY10789
Artikelnummer: TGM-T60439-10mg
Description: CAY10789 (compound 6) is a potent CysLT1R (cysteinyl leukotriene receptor 1) antagonist with an IC50 of 2.80 µM and a GPBAR1 (G-protein-coupled bile acid receptor 1) agonist with an EC50 of 3 µM. It significantly decreases U937 cell adhesion to HAEC and reduces TNF-alpha expression. CAY10789...
| Anwendung: | CysLT1 receptor antagonist |
| CAS | 123226-28-8 |
| MW: | 265.31 D |
ab 108,00 €
Pranlukast hemihydrate
Artikelnummer: TGM-T63291-25mg
Description: Pranlukast hemihydrate is a selective, potent and competitive antagonist of leukotriene.Pranlukast inhibits [3H]LTE4 (Ki: 0.63±0.11 nM), [3H]LTD4 (Ki: 0.99±0.19 nM) and [3H]LTC4 (Ki: 5640 ±680 nM) were bound to the lung membrane. Target: Others. Smiles:...
| Anwendung: | Targets cysteinyl leukotriene receptor 1 (CYSLTR1) |
| CAS | 150821-03-7 |
| MW: | 981.039 D |
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CAY10788
Artikelnummer: TGM-T71273-10mg
Description: CAY10788 is an antagonist of CysLT1 receptor. Target: Others. Smiles: C(OC1=CC(C(OC)=O)=CC=C1)C2=NC3=C(C=C2)C=CC=C3
| Anwendung: | CysLT1 receptor antagonist |
| CAS | 119515-00-3 |
| MW: | 293.32 D |
ab 77,00 €
FPL-55712
Artikelnummer: TGM-T69278-10mg
Description: FPL-55712 is a CysLT1 leukotriene receptor antagonist. Target: Others
| Anwendung: | Leukotriene receptor antagonist |
| CAS | 40786-08-1 |
| MW: | 520.5098 D |
ab 72,00 €