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Zu "K04298" wurden 34 Artikel gefunden!
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NEU
Artikelnummer: CSB-CF861428MO.100
Organism: Mus musculus (Mouse). Source: in vitro E.coli expression system. Expression Region: 1-347aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MDVPGVNTTS ANTTFSPGTS TLCVRDYKIT QVLFPLLYTV LFFAGLITNS LAMRIFFQIR SKSNFIIFLK NTVISDLLMI LTFPFKILSD AKLGAGPLRT LVCQVTSVTF...
Schlagworte: | P2Y12, P2ry12, P2Y purinoceptor 12, Recombinant Mouse P2Y purinoceptor 12 (P2ry12) |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli in vitro |
Ursprungsart: | mouse |
MW: | 45.5 kD |
ab 1.413,00 €
NEU
Artikelnummer: CSB-CF861997HU.100
Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 1-342aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MQAVDNLTSA PGNTSLCTRD YKITQVLFPL LYTVLFFVGL ITNGLAMRIF FQIRSKSNFI IFLKNTVISD LLMILTFPFK ILSDAKLGTG PLRTFVCQVT SVIFYFTMYI...
Schlagworte: | P2Y12, HORK3, SP1999, ADPG-R, P2RY12, P2T(AC), P2Y(AC), P2Y(cyc), P2Y(ADP), P2Y purinoceptor 12, ADP-glucose receptor,... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli in vitro |
Ursprungsart: | human |
MW: | 42.2 kD |
ab 1.413,00 €
Artikelnummer: Cay15425-5
Ticagrelor is a reversible antagonist of the platelet purinergic P2Y12 receptor (Ki = 14 nM, IC50 = 1.8 µM), which is the main receptor responsible for ADP-induced platelet aggregation. It functions by directly changing the conformation of the P2Y12 receptor to inhibit ADP binding. Formulations containing ticagrelor...
Schlagworte: | AR-C 126532XX, AZD 6140,... |
Anwendung: | P2Y12 receptor antagonist |
CAS | 274693-27-5 |
MW: | 522.6 D |
ab 43,00 €
Artikelnummer: Cay63250-1
Farnesyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway and used in the biosynthesis of terpenes, terpenoids, and sterols. It also serves as a donor in post-translational isoprenylation of proteins. FPP has been identified as an antagonist of P2Y12 receptors (IC50 = 45 µM), attenuating platelet...
Schlagworte: | FPP, P-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl] ester-diphosphoric acid, triammonium salt |
Anwendung: | P2Y12 receptor antagonist |
CAS | 116057-57-9 |
MW: | 433.4 D |
ab 92,00 €
Artikelnummer: ELK-ELK4385.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human P2RY12. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human P2RY12....
Schlagworte: | P2Y12, HORK3, SP1999, P2RY12, ADPG-R, P2Y(AC), P2T(AC), P2Y(cyc), P2Y(ADP), P2Y purinoceptor 12, ADP-glucose receptor,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay21230-1
2-Methylthioadenosine diphosphate (2-MeSADP) is an agonist of purinergic P2Y receptors with EC50s of 5.13 and 0.89 nM for human recombinant P2Y1 and P2Y12 receptors, respectively. It also acts as an agonist at rat P2Y1 and P2Y12 and mouse P2Y13 receptors (EC50s = 0.58, 0.89, and 6.2 nM, respectively). It induces...
Schlagworte: | 2-MeSADP, 2-Methylthio-ADP, 2-(methylthio)-adenosine 5'-(trihydrogen diphosphate), trisodium salt |
Anwendung: | P2RY1 / P2RY12 / P2Y13 agonist |
CAS | 475193-31-8 |
MW: | 539.2 D |
ab 77,00 €
Artikelnummer: Cay13657-10
(±)-Clopidogrel is a racemic mixture of (R)-(-)- clopidogrel and the prodrug form of the active metabolite of clopidogrel (S)-(+)-clopidogrel (Cay-21002).Formal Name: alpha-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid, methyl ester, monohydrochloride. CAS Number: 130209-90-4. Molecular...
Schlagworte: | alpha-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid, methyl ester, monohydrochloride |
Anwendung: | P2Y12 receptor antagonist |
CAS | 130209-90-4 |
MW: | 358.3 D |
ab 185,00 €
Artikelnummer: Cay20394-5
2-oxo Clopidogrel is an intermediate metabolite of (±)-clopidogrel (Cay-13657), which consists of R-(-)-clopidogrel and the active isomer S-(+)-clopidogrel (Cay-21002). (S)-(+)-clopidogrel is metabolized by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 into 2-oxo (S)-(+)-clopidogrel, which is then further...
Schlagworte: | alpha-(2-chlorophenyl)-2,6,7,7a-tetrahydro-2-oxo-thieno[3,2-c]pyridine-5(4H)-acetic acid, methyl ester |
Anwendung: | P2RY12 irreversible inhibitor prodrug |
CAS | 109904-27-0 |
MW: | 337.8 D |
ab 66,00 €
Artikelnummer: LKT-T3200.5
Ticagrelor is a platelet aggregation inhibitor. It is a nucleoside analogue and blocks adenosine diphosphate (ADP) receptors of subtype P2Y12. In contrast to the other antiplatelet drugs, ticagrelor has a binding site different from ADP, making it an allosteric antagonist, and the blockage is reversible. The drug...
Schlagworte: | AZD-6140, (1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino]-5-(propylthio)-... |
Anwendung: | P2Y12 receptor antagonist |
CAS | 274693-27-5 |
MW: | 522.57 D |
ab 77,00 €
Artikelnummer: Cay20770-1
Ticlopidine is a thienopyridine P2Y12 receptor antagonist. It inhibits aggregation of human platelets induced by collagen, arachidonic acid (Cay-90010), and ADP (Cay-16778, IC50s = 75, 600, and 1,300 µM, respectively). It also inhibits ADP-induced aggregation of rat platelets and decreases thrombus weight in vivo in...
Schlagworte: | 5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine, monohydrochloride |
Anwendung: | Anticoagulant, Platelet aggregation inhibitor, Purinergic receptor P2Y12 antagonist |
CAS | 53885-35-1 |
MW: | 300.2 D |
ab 43,00 €
Artikelnummer: Cay25027-1
Ticagrelor-d7 is intended for use as an internal standard for the quantification of ticagrelor (Cay-15425) by GC- or LC-MS. Ticagrelor is a reversible antagonist of the platelet purinergic P2Y12 receptor (Ki = 14 nM, IC50 = 1.8 µM), which is the main receptor responsible for ADP-induced platelet aggregation. It...
Schlagworte: | (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propyl-1,1,2,2,3,3,3-d7-thio)-3H-1,2,3-triazolo[4... |
Anwendung: | Internal standard, GC-MS, LC-MS |
CAS | 1265911-55-4 |
MW: | 529.6 D |
693,00 €
Artikelnummer: Cay21002-25
(S)-(+)-Clopidogrel is a prodrug form of the active metabolite of clopidogrel, which is a purinergic P2Y12 receptor antagonist. It inhibits aggregation of rat platelets induced by ADP, collagen, and thrombin ex vivo (ID50s = 4, 4.8, and 2.9 mg/kg). (S)-(+)-Clopidogrel increases tail bleeding time in rats in a...
Schlagworte: | SR 25990C, S-alpha-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid, methyl ester, monosulfate |
Anwendung: | P2Y12 receptor antagonist |
CAS | 120202-66-6 |
MW: | 419.9 D |
ab 43,00 €